You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function

Authors:
Houbrechts AM, Vergauwen L, Bagci E, Van Houcke J, Heijlen M, Kulemeka B, Hyde DR, Knapen D, Darras VM
Citation:
Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30018-1. doi: 10.1016/j.mce.2016.01.018. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinal development in vertebrates relies extensively on thyroid hormones. Their local availability is tightly controlled by...
Link:
http://www.sciencedirect.com/science/article/pii/S0303720716300181
Organism or Cell Type:
zebrafish
Citation Extract:
Houbrechts AM, Vergauwen L, Bagci E, Van Houcke J, Heijlen M, Kulemeka B, Hyde DR, Knapen D, Darras VM. Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function. Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30018-1. doi: 10.1016/j.mce.2016.01.018. [Epub ahead of print].

GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway

Authors:
Chen Z, Wan X, Hou Q, Shi S, Wang L, Chen P, Zhu X, Zeng C, Qin W, Zhou W, Liu Z
Citation:
Cell Death Dis. 2016 Jan 21;7:e2068. doi: 10.1038/cddis.2015.300
Epub:
Not Epub
Abstract:
GADD45 gene has been implicated in cell cycle arrest, cell survival or apoptosis in a cell type specific and context-dependent...
Link:
http://www.nature.com/cddis/journal/v7/n1/full/cddis2015300a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Z, Wan X, Hou Q, Shi S, Wang L, Chen P, Zhu X, Zeng C, Qin W, Zhou W, Liu Z. GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway. Cell Death Dis. 2016 Jan 21;7:e2068. doi: 10.1038/cddis.2015.300.

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

Authors:
Mamińska A, Anna Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon T, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M
Citation:
Sci Signal. 2016;9(411):ra8. doi:10.1126/scisignal.aad0848
Epub:
Not Epub
Abstract:
Because signaling mediated by the transcription factor nuclear factor κB (NF-κB) is initiated by ligands and receptors that can...
Link:
http://stke.sciencemag.org/content/9/411/ra8
Organism or Cell Type:
zebrafish
Citation Extract:
Mamińska A, Anna Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon T, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M. ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors. Sci Signal. 2016;9(411):ra8. doi:10.1126/scisignal.aad0848.

Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells

Authors:
Vad-Nielsen J, Jakobsen KR, Daugaard TF, Thomsen R, Brügmann A, Sørensen BS, Nielsen AL
Citation:
BMC Cancer. 2016;16:32. doi:10.1186/s12885-016-2059-x
Epub:
Not Epub
Abstract:
Background: The three members of the human heterochromatin protein 1 (HP1) family of proteins, HP1α, HP1β, and HPγ, are...
Link:
http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2059-x
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: MDA-MB-231
Citation Extract:
Vad-Nielsen J, Jakobsen KR, Daugaard TF, Thomsen R, Brügmann A, Sørensen BS, Nielsen AL. Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells. BMC Cancer. 2016;16:32. doi:10.1186/s12885-016-2059-x.

Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling

Authors:
Zhao Y, Shi J, Winey M, Klymkowsky MW
Citation:
Dev Biol. 2016 Jan 16. pii: S0012-1606(15)30212-8. doi: 10.1016/j.ydbio.2016.01.004. [Epub ahead of print]
Epub:
Not Epub
Abstract:
EFHC1 encodes a ciliary protein that has been linked to Juvenile Myoclonic Epilepsy. In ectodermal explants, derived from...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615302128
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhao Y, Shi J, Winey M, Klymkowsky MW. Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling. Dev Biol. 2016 Jan 16. pii: S0012-1606(15)30212-8. doi: 10.1016/j.ydbio.2016.01.004. [Epub ahead of print].

Microtubule-associated protein 1b is required for shaping the neural tube

Authors:
Jayachandran P, Olmo VN, Sanchez SP, McFarland RJ, Vital E, Werner JM, Hong E, Sanchez-Alberola N, Molodstov A, Brewster RM
Citation:
Neural Dev. 2016 Jan 18;11(1):1. doi: 10.1186/s13064-015-0056-4
Epub:
Not Epub
Abstract:
BACKGROUND: Shaping of the neural tube, the precursor of the brain and spinal cord, involves narrowing and elongation of the...
Link:
http://neuraldevelopment.biomedcentral.com/articles/10.1186/s13064-015-0056-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jayachandran P, Olmo VN, Sanchez SP, McFarland RJ, Vital E, Werner JM, Hong E, Sanchez-Alberola N, Molodstov A, Brewster RM. Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev. 2016 Jan 18;11(1):1. doi: 10.1186/s13064-015-0056-4.

Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development

Authors:
Schille C, Heller J, Schambony A
Citation:
BMC Dev Biol. 2016;[Epub ahead of print] doi:10.1186/s12861-016-0101-5
Epub:
Not Epub
Abstract:
Background: Bone morphogenetic proteins regulate multiple processes in embryonic development, including early dorso-ventral...
Link:
http://bmcdevbiol.biomedcentral.com/articles/10.1186/s12861-016-0101-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schille C, Heller J, Schambony A. Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development. BMC Dev Biol. 2016;[Epub ahead of print] doi:10.1186/s12861-016-0101-5.

Evolution of the fish heart by sub/neofunctionalization of an elastin gene

Authors:
Moriyama Y, Ito F, Takeda H, Yano T, Okabe M, Kuraku S, Keeley FW, Koshiba-Takeuchi K
Citation:
Nat Comm. 2016;7:10397. doi:10.1038/ncomms10397
Epub:
Not Epub
Abstract:
The evolution of phenotypic traits is a key process in diversification of life. However, the mechanisms underlying the...
Link:
http://www.nature.com/ncomms/2016/160119/ncomms10397/full/ncomms10397.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moriyama Y, Ito F, Takeda H, Yano T, Okabe M, Kuraku S, Keeley FW, Koshiba-Takeuchi K. Evolution of the fish heart by sub/neofunctionalization of an elastin gene. Nat Comm. 2016;7:10397. doi:10.1038/ncomms10397.

The morpholino molecular beacon for specific RNA visualization in vivo.

Authors:
Chen J, Wu J, Hong Y
Citation:
Chem Commun (Camb). 2016 Feb 21;52(15):3191-4. doi: 10.1039/c5cc07124k
Epub:
Yes
Abstract:
A non-invasive fluorescent probe, morpholino molecular beacon (MO-MB), was designed for RNA visualization in vivo. Featuring...
Link:
http://pubs.rsc.org/en/Content/ArticleLanding/2016/CC/C5CC07124K#!divAbstract
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Chen J, Wu J, Hong Y. The morpholino molecular beacon for specific RNA visualization in vivo.. Chem Commun (Camb). 2016 Feb 21;52(15):3191-4. doi: 10.1039/c5cc07124k.

A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions

Authors:
Oliver VF, van Bysterveldt KA, Cadzow M, Steger B, Romano V, Markie D, Hewitt AW, Mackey DA, Willoughby CE, Sherwin T, Crosier PS, McGhee CN, Vincent AL
Citation:
Ophthalmol. 2016;[Epub ahead of print] doi:10.1016/j.ophtha.2015.12.008
Epub:
Not Epub
Abstract:
Purpose: Corneal dystrophies are a genetically heterogeneous group of disorders. We previously described a family with an...
Link:
http://www.aaojournal.org/article/S0161-6420%2815%2901432-3/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oliver VF, van Bysterveldt KA, Cadzow M, Steger B, Romano V, Markie D, Hewitt AW, Mackey DA, Willoughby CE, Sherwin T, Crosier PS, McGhee CN, Vincent AL. A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions. Ophthalmol. 2016;[Epub ahead of print] doi:10.1016/j.ophtha.2015.12.008.

Pages