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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
An oxygen-insensitive Hif-3a isoform inhibits Wnt signaling by destabilizing the nuclear b-catenin complex
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Citation:
eLife. 2016;10.7554/eLife.08996 doi:10.7554/eLife.08996 Epub:
Not Epub Abstract:
Hypoxia-inducible factors (HIFs), while best known for their roles in the hypoxic response, have oxygen-independent roles in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang P, Bai Y, Lu L, Li Y, Duan C. An oxygen-insensitive Hif-3a isoform inhibits Wnt signaling by destabilizing the nuclear b-catenin complex. eLife. 2016;10.7554/eLife.08996 doi:10.7554/eLife.08996. |
The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes
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Citation:
Nucleic Acids Res. 1997 Nov 15;25(22):4429-43 Epub:
Not Epub Abstract:
In an effort to discover novel oligonucleotide modifications for antisense therapeutics, we have prepared... Citation Extract: Freier SM, Altmann KH . The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes. Nucleic Acids Res. 1997 Nov 15;25(22):4429-43. |
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer
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Citation:
Nat Comm. 2016;7:10310. doi:10.1038/ncomms10318 Epub:
Not Epub Abstract:
The non-canonical Wnt/planar cell polarity (Wnt/PCP) pathway plays a crucial role in embryonic development. Recent work has... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, Collette Y, Gonçalvès A, Macara I, Birnbaum D, Kodjabachian L, Johansen T, Borg J-P. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer. Nat Comm. 2016;7:10310. doi:10.1038/ncomms10318. |
Emergence of an Apical Epithelial Cell Surface In Vivo
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Citation:
Dev Biol. 2016;36(1)24-35. doi:10.1016/j.devcel.2015.12.013 Epub:
Not Epub Abstract:
Epithelial sheets are crucial components of all metazoan animals, enclosing organs and protecting the animal from its... Delivery Method:
microinjection Citation Extract: Sedzinski J, Hannezo E, Tu F, Biro M, Wallingford JB. Emergence of an Apical Epithelial Cell Surface In Vivo. Dev Biol. 2016;36(1)24-35. doi:10.1016/j.devcel.2015.12.013. |
Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation
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Citation:
Nat Struct Mol Biol. 2016 Jan 11. doi: 10.1038/nsmb.3151. [Epub ahead of print] Epub:
Yes Abstract:
DNA 5-methylcytosine is a dynamic epigenetic mark with important roles in development and disease. In the Tet-Tdg demethylation... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Schomacher L, Han D, Musheev MU, Arab K, Kienhöfer S, von Seggern A, Niehrs C. Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation. Nat Struct Mol Biol. 2016 Jan 11. doi: 10.1038/nsmb.3151. [Epub ahead of print]. |
Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies
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Citation:
PLoS One. 2016 Jan 8;11(1):e0145620. doi: 10.1371/journal.pone.0145620. eCollection 2016 Epub:
Not Epub Abstract:
Duchenne and Becker muscular dystrophy severity depends upon the nature and location of the DMD gene lesion and generally... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Toh ZY, Thandar Aung-Htut M, Pinniger G, Adams AM, Krishnaswarmy S, Wong BL, Fletcher S, Wilton SD. Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies. PLoS One. 2016 Jan 8;11(1):e0145620. doi: 10.1371/journal.pone.0145620. eCollection 2016. |
Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation
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Citation:
Genetics. 2016 Jan;202(1):123-39. doi: 10.1534/genetics.115.183137. Epub 2015 Oct 4 Epub:
Not Epub Abstract:
Neural tube defects including spina bifida are common and severe congenital disorders. In mice, mutations in more than 200... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Sullivan-Brown JL, Tandon P, Bird KE, Dickinson DJ, Tintori SC, Heppert JK, Meserve JH, Trogden KP, Orlowski SK, Conlon FL, Goldstein B. Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation. Genetics. 2016 Jan;202(1):123-39. doi: 10.1534/genetics.115.183137. Epub 2015 Oct 4. |
PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress
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Citation:
Sci Rep. 2016 Jan 6;6:18846. doi: 10.1038/srep18846 Epub:
Not Epub Abstract:
Ribonucleotide reductase small subunit B (RRM2B) is a stress response protein that protects normal human fibroblasts from... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuo ML, Lee MB, Tang M, den Besten W, Hu S, Sweredoski MJ, Hess S, Chou CM, Changou CA, Su M, Jia W, Su L, Yen Y. PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress. Sci Rep. 2016 Jan 6;6:18846. doi: 10.1038/srep18846. |
Visualization of Assembly Intermediates and Budding Vacuoles of Singapore Grouper Iridovirus in Grouper Embryonic Cells
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Citation:
Sci Rep. 2016 Jan 4;6:18696. doi: 10.1038/srep18696 Epub:
Not Epub Abstract:
Iridovirid infection is associated with the catastrophic loss in aquaculture industry and the population decline of wild... Delivery Method:
electroporation Organism or Cell Type:
cell culture: Grouper embryonic cells (GECs) from Epinephelus tauvina Citation Extract: Liu Y, Tran BN, Wang F, Ounjai P, Wu J, Hew CL. Visualization of Assembly Intermediates and Budding Vacuoles of Singapore Grouper Iridovirus in Grouper Embryonic Cells. Sci Rep. 2016 Jan 4;6:18696. doi: 10.1038/srep18696. |
Cdx4 and Retinoic Acid Interact to Position the Hindbrain-Spinal Cord Transition
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Citation:
Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2015.12.025 Epub:
Yes Abstract:
The sub-division of the posterior-most territory of the neural plate results in the formation of two distinct neural structures... Organism or Cell Type:
zebrafish Citation Extract: Chang J, Skromne I, Ho RK. Cdx4 and Retinoic Acid Interact to Position the Hindbrain-Spinal Cord Transition. Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2015.12.025. |