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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Hatching gland development and hatching in zebrafish embryos: A role for zinc and its transporters Zip10 and Znt1a

Authors:
Muraina IA, Maret W, Bury NR, Hogstrand C
Citation:
Biochem Biophys Res Comm. 2020;[Epub ahead of print] doi:10.1016/j.bbrc.2020.05.131
Epub:
Yes
Abstract:
Zinc transporters of the ZIP (Slc39, importers) and ZnT (Slc30, exporters) protein families have evolutionary conserved roles...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X20310603
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Muraina IA, Maret W, Bury NR, Hogstrand C. Hatching gland development and hatching in zebrafish embryos: A role for zinc and its transporters Zip10 and Znt1a. Biochem Biophys Res Comm. 2020;[Epub ahead of print] doi:10.1016/j.bbrc.2020.05.131.

Exon skipping of TGFβRI affects signalling and ECM expression in hypertrophic scar-derived fibroblasts

Authors:
Raktoe RS, Rietveld MH, Out-Luiting JJ, Kruithof-de Julio M, van Zuijlen PPM, van Doorn R, El Ghalbzouri A
Citation:
Scars Burn. Heal. 2020;6;[Epub] doi:10.1177/2059513120908857
Epub:
Not Epub
Abstract:
Background: In burn patients, wound healing is often accompanied by hypertrophic scar (HS) development, resulting in both...
Link:
https://journals.sagepub.com/doi/full/10.1177/2059513120908857
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: primary human fibroblasts
Citation Extract:
Raktoe RS, Rietveld MH, Out-Luiting JJ, Kruithof-de Julio M, van Zuijlen PPM, van Doorn R, El Ghalbzouri A. Exon skipping of TGFβRI affects signalling and ECM expression in hypertrophic scar-derived fibroblasts. Scars Burn. Heal. 2020;6;[Epub] doi:10.1177/2059513120908857.

Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress

Authors:
Kröll‐Hermi A, Ebstein F, Stoetzel C, Geoffroy V, Schaefer E, Scheidecker S, Bär S, Takamiya M, Kawakami K, Zieba BA, Studer F, Pelletier V, Eyermann C, Speeg‐Schatz C, Laugel V, Lipsker D, Sandron F, McGinn S, Boland A, Deleuze J-F, Kuhn L, Chicher J, Hammann P, Friant S, Etard C, Krüger E, Muller J, Strähle U, Dollfus H
Citation:
EMBO Mol Med. 2020;e11861 [Epub] doi:10.15252/emmm.201911861
Epub:
Yes
Abstract:
The ubiquitin–proteasome system degrades ubiquitin‐modified proteins to maintain protein homeostasis and to control signalling...
Link:
https://www.embopress.org/doi/10.15252/emmm.201911861
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kröll‐Hermi A, Ebstein F, Stoetzel C, Geoffroy V, Schaefer E, Scheidecker S, Bär S, Takamiya M, Kawakami K, Zieba BA, Studer F, Pelletier V, Eyermann C, Speeg‐Schatz C, Laugel V, Lipsker D, Sandron F, McGinn S, Boland A, Deleuze J-F, Kuhn L, Chicher J, Hammann P, Friant S, Etard C, Krüger E, Muller J, Strähle U, Dollfus H . Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress. EMBO Mol Med. 2020;e11861 [Epub] doi:10.15252/emmm.201911861.

Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm Signals

Authors:
Poplimont H, Georgantzoglou A, Boulch M, Walker HA, Coombs C, Papaleonidopoulou F, Sarris M
Citation:
Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.05.030
Epub:
Yes
Abstract:
Neutrophils are major inflammatory cells that rapidly infiltrate wounds to provide antimicrobial functions. Within the damaged...
Link:
https://www.cell.com/current-biology/fulltext/S0960-9822(20)30669-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poplimont H, Georgantzoglou A, Boulch M, Walker HA, Coombs C, Papaleonidopoulou F, Sarris M. Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm Signals. Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.05.030.

LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling

Authors:
Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJE, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, Cariboni A, Bonomi M, Garcia MI, Guasti L, Dunkel L
Citation:
JCI Insight. 2020;[Epub ahead of print] doi:10.1172/jci.insight.133434
Epub:
Yes
Abstract:
The initiation of puberty is driven by an upsurge in hypothalamic gonadotropin-releasing hormone (GnRH) secretion. In turn,...
Link:
https://insight.jci.org/articles/view/133434
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJE, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, Cariboni A, Bonomi M, Garcia MI, Guasti L, Dunkel L. LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling. JCI Insight. 2020;[Epub ahead of print] doi:10.1172/jci.insight.133434.

Knockdown of hspg2 is associated with mandibular jaw joint fusion and neural crest cell dysfunction in zebrafish

Authors:
Castellanos BS, Quintana A
Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-27670/v1
Epub:
Not Epub
Abstract:
Background: Heparan sulfate proteoglycan 2 (HSPG2) encodes for perlecan, a large proteoglycan that plays an important role in...
Link:
https://www.researchsquare.com/article/rs-27670/v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Castellanos BS, Quintana A. Knockdown of hspg2 is associated with mandibular jaw joint fusion and neural crest cell dysfunction in zebrafish. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-27670/v1.

Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle

Authors:
Chestnut B, Casie Chetty S, Koenig AL, Sumanas S
Citation:
Nat Commun. 2020;11:2796. doi:10.1038/s41467-020-16515-y
Epub:
Not Epub
Abstract:
Cell fate decisions involved in vascular and hematopoietic embryonic development are still poorly understood. An ETS...
Link:
https://www.nature.com/articles/s41467-020-16515-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chestnut B, Casie Chetty S, Koenig AL, Sumanas S. Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle. Nat Commun. 2020;11:2796. doi:10.1038/s41467-020-16515-y.

Extra-hypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance

Authors:
Duque-Wilckens N, Torres L, Yokoyama S, Minie V, Tran A, Petkova S, Hao R, Ramos-Maciel S, Rioa R, Jackson K, Flores-Ramirez F, Garcia-Carachure I, Pesavento PA, Iniguez S, Grinevich V, Trainor BC
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.06.02.129981
Epub:
Not Epub
Abstract:
Oxytocin increases the salience of both positive and negative social contexts and it is thought that these diverse actions on...
Link:
https://www.biorxiv.org/content/10.1101/2020.06.02.129981v1
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Duque-Wilckens N, Torres L, Yokoyama S, Minie V, Tran A, Petkova S, Hao R, Ramos-Maciel S, Rioa R, Jackson K, Flores-Ramirez F, Garcia-Carachure I, Pesavento PA, Iniguez S, Grinevich V, Trainor BC. Extra-hypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance. bioRxiv. 2020;[preprint] doi:10.1101/2020.06.02.129981 .

Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos

Authors:
Choe S, Huh TL, Rhee M
Citation:
Anim Cells Syst (Seoul). 2020 Apr 22;24(2):99-106. doi: 10.1080/19768354.2020.1751281
Epub:
Not Epub
Abstract:
Trim45 is one of the RING (really interesting new gene) finger containing E3 ligase, which belongs to TRIM (Tripartite motif)...
Link:
https://pubmed.ncbi.nlm.nih.gov/32489689/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choe S, Huh TL, Rhee M. Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos. Anim Cells Syst (Seoul). 2020 Apr 22;24(2):99-106. doi: 10.1080/19768354.2020.1751281.

CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia

Authors:
Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J
Citation:
Proc Natl Acad Sci U S A. 2020 Jun 1:201907335. doi: 10.1073/pnas.1907335117. Online ahead of print
Epub:
Not Epub
Abstract:
Synchronized beating of cilia on multiciliated cells (MCCs) generates a directional flow of mucus across epithelia. This...
Link:
https://www.pnas.org/content/early/2020/05/28/1907335117
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J. CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia. Proc Natl Acad Sci U S A. 2020 Jun 1:201907335. doi: 10.1073/pnas.1907335117. Online ahead of print.

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