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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12308 scientific papers returned from the database with the search filters currently being used below.

Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells

Authors:
Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP
Citation:
J Physiol. 2020 Jul 6. doi: 10.1113/JP279947. Online ahead of print
Epub:
Yes
Abstract:
In vascular smooth muscle cells (VMSCs), stimulation of Ca2+ -permeable canonical transient receptor potential channel 1 (TRPC1...
Link:
https://physoc.onlinelibrary.wiley.com/doi/abs/10.1113/JP279947
Organism or Cell Type:
cell culture: contractile rat mesenteric artery vascular smooth muscle cells (VMSCs)
Citation Extract:
Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP. Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells. J Physiol. 2020 Jul 6. doi: 10.1113/JP279947. Online ahead of print.

A Novel Micropeptide Encoded by Y-Linked LINC00278 Links Cigarette Smoking and AR Signaling in Male Esophageal Squamous Cell Carcinoma

Authors:
Wu S, Zhang L, Deng J, Guo B, Li F, Wang Y, Wu R, Zhang S, Lu J, Zhou Y
Citation:
Cancer Res. 2020 Mar 13:canres.3440.2019. doi: 10.1158/0008-5472.CAN-19-3440. Online ahead of print
Epub:
Yes
Abstract:
Long non-coding RNAs (lncRNA) have been shown to play critical roles in many diseases, including esophageal squamous cell...
Link:
https://cancerres.aacrjournals.org/content/80/13/2790
Organism or Cell Type:
cell culture:Het-1A, xenograft Esophageal Squamous Cell Carcinoma
Citation Extract:
Wu S, Zhang L, Deng J, Guo B, Li F, Wang Y, Wu R, Zhang S, Lu J, Zhou Y. A Novel Micropeptide Encoded by Y-Linked LINC00278 Links Cigarette Smoking and AR Signaling in Male Esophageal Squamous Cell Carcinoma. Cancer Res. 2020 Mar 13:canres.3440.2019. doi: 10.1158/0008-5472.CAN-19-3440. Online ahead of print.

Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System

Authors:
Guerra J, Chiodelli P, Tobia C, Gerri C, Presta M
Citation:
Cancer 2020;12:1756. doi:10.3390/cancers12071756
Epub:
Not Epub
Abstract:
Primary cilium drives the left-right asymmetry process during embryonic development. Moreover, its dysregulation contributes to...
Link:
https://www.mdpi.com/2072-6694/12/7/1756
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guerra J, Chiodelli P, Tobia C, Gerri C, Presta M. Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System. Cancer 2020;12:1756. doi:10.3390/cancers12071756 .

Asymmetric neurogenic commitment of retinal progenitors involves Notch through the endocytic pathway

Authors:
Nerli E, Rocha-Martins M, Norden C
Citation:
Elife. 2020 Nov 3;9:e60462. doi: 10.7554/eLife.60462. PMID: 33141024; PMCID: PMC7679139
Epub:
Not Epub
Abstract:
During brain development, progenitor cells need to balanceproliferation and differentiation in order to generate different...
Link:
https://elifesciences.org/articles/60462
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nerli E, Rocha-Martins M, Norden C. Asymmetric neurogenic commitment of retinal progenitors involves Notch through the endocytic pathway. Elife. 2020 Nov 3;9:e60462. doi: 10.7554/eLife.60462. PMID: 33141024; PMCID: PMC7679139.

Disabled-2: a positive regulator of the early differentiation of myoblasts

Authors:
Shang N, Lee JTY, Huang T, Wang C, Lee TL, Mok SC, Zhao H, Chan WY
Citation:
Cell Tissue Res. 2020 Jun 30;[Epub ahead of print] doi: 10.1007/s00441-020-03237-2. Online ahead of print
Epub:
Yes
Abstract:
Dab2 is an adaptor protein and a tumor suppressor. Our previous study has found that Dab2 was expressed in early...
Link:
https://link.springer.com/article/10.1007%2Fs00441-020-03237-2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shang N, Lee JTY, Huang T, Wang C, Lee TL, Mok SC, Zhao H, Chan WY. Disabled-2: a positive regulator of the early differentiation of myoblasts. Cell Tissue Res. 2020 Jun 30;[Epub ahead of print] doi: 10.1007/s00441-020-03237-2. Online ahead of print.

A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation

Authors:
Ray D, Yu CY, Idris M, Cheng S, Boot A, Tan BHI, Rozen SG, Tan P, Epstein DM
Citation:
Proc Nat Acad Sci USA. 2020:202002499 [Epub ahead of print] doi:10.1073/pnas.2002499117
Epub:
Yes
Abstract:
Master splicing regulator MBNL1 shapes large transcriptomic changes that drive cellular differentiation during development....
Link:
https://www.pnas.org/content/early/2020/06/25/2002499117
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: HFE-145
Citation Extract:
Ray D, Yu CY, Idris M, Cheng S, Boot A, Tan BHI, Rozen SG, Tan P, Epstein DM. A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation. Proc Nat Acad Sci USA. 2020:202002499 [Epub ahead of print] doi:10.1073/pnas.2002499117.

Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk

Authors:
Pineda S, Nikolova-Krstevski V, Leimena C, Atkinson AJ, Altekoester AK, Cox CD, Jacoby A, Huttner IG, Ju YK, Soka M, Ohanian M, Trivedi G, Kalvakuri S, Birker K, Johnson R, Molenaar P, Kuchar D, Allen DG, van Helden DF, Harvey RP, Hill AP, Bodmer R, Vogler G, Dobrzynski H, Ocorr K, Fatkin D
Citation:
Circ Genom Precis Med. 2021 Apr;14(2):e003144. doi: 10.1161/CIRCGEN.120.003144. Epub 2021 Feb 25. PMID: 33629867; PMCID: PMC8058291
Epub:
Not Epub
Abstract:
Background: KCNMA1 encodes the α-subunit of the large-conductance Ca2+-activated K+ channel, KCa1.1, and lies within a linkage...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8058291/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pineda S, Nikolova-Krstevski V, Leimena C, Atkinson AJ, Altekoester AK, Cox CD, Jacoby A, Huttner IG, Ju YK, Soka M, Ohanian M, Trivedi G, Kalvakuri S, Birker K, Johnson R, Molenaar P, Kuchar D, Allen DG, van Helden DF, Harvey RP, Hill AP, Bodmer R, Vogler G, Dobrzynski H, Ocorr K, Fatkin D. Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk. Circ Genom Precis Med. 2021 Apr;14(2):e003144. doi: 10.1161/CIRCGEN.120.003144. Epub 2021 Feb 25. PMID: 33629867; PMCID: PMC8058291.

Dopachrome tautomerase variants in patients with oculocutaneous albinism

Authors:
Pennamen P, Tingaud-Sequeira A, Gazova I, Keighren M, McKie L, Marlin S, Gherbi Halem S, Kaplan J, Delevoye C, Lacombe D, Plaisant C, Michaud V, Lasseaux E, Javerzat S, Jackson I, Arveiler B
Citation:
Genet Med. 2021 Mar;23(3):479-487. doi: 10.1038/s41436-020-00997-8. Epub 2020 Oct 26. PMID: 33100333
Epub:
Not Epub
Abstract:
Purpose: Albinism is a clinically and genetically heterogeneous condition. Despite analysis of the 20 known genes, ~30%...
Link:
https://www.gimjournal.org/article/S1098-3600(21)04940-6/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pennamen P, Tingaud-Sequeira A, Gazova I, Keighren M, McKie L, Marlin S, Gherbi Halem S, Kaplan J, Delevoye C, Lacombe D, Plaisant C, Michaud V, Lasseaux E, Javerzat S, Jackson I, Arveiler B. Dopachrome tautomerase variants in patients with oculocutaneous albinism. Genet Med. 2021 Mar;23(3):479-487. doi: 10.1038/s41436-020-00997-8. Epub 2020 Oct 26. PMID: 33100333.

Schwann cells selectively myelinate primary motor axons via neuregulin‐ErbB signaling

Authors:
Lee D-W, Kim E, Inyoung Jeong I, Hwan‐Ki Kim H-K, Suhyun Kim S, Hae‐Chul Park H-C
Citation:
Glia. 2020;[Epub ahead of print] doi:10.1002/glia.23871
Epub:
Not Epub
Abstract:
Spinal motor neurons project their axons out of the spinal cord via the motor exit point (MEP) and regulate their target muscle...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1002/glia.23871
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee D-W, Kim E, Inyoung Jeong I, Hwan‐Ki Kim H-K, Suhyun Kim S, Hae‐Chul Park H-C. Schwann cells selectively myelinate primary motor axons via neuregulin‐ErbB signaling. Glia. 2020;[Epub ahead of print] doi:10.1002/glia.23871.

Epb41l5 interacts with Iqcb1 and regulates ciliary function in zebrafish embryos

Authors:
Yu T, Matsuda M
Citation:
J Cell Sci. 2020;133(12):jcs240648 doi:10.1242/jcs.240648
Epub:
Not Epub
Abstract:
Erythrocyte protein band 4.1 like 5 (EPB41L5) is an adaptor protein beneath the plasma membrane that functions to control...
Link:
https://jcs.biologists.org/content/133/12/jcs240648
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu T, Matsuda M. Epb41l5 interacts with Iqcb1 and regulates ciliary function in zebrafish embryos. J Cell Sci. 2020;133(12):jcs240648 doi:10.1242/jcs.240648.

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