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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Lmo7a Coordinates Neural Crest Migration and Lineage Specification by Regulating Cell Adhesion Dynamics

Authors:
Tatarakis DM, Tuttle A, Schilling TF
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.30.125468
Epub:
Not Epub
Abstract:
Cell migration requires dynamic regulation of cell-cell signaling and cell adhesion. Neural crest (NC) cells are highly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tatarakis DM, Tuttle A, Schilling TF. Lmo7a Coordinates Neural Crest Migration and Lineage Specification by Regulating Cell Adhesion Dynamics. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.30.125468 .

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Authors:
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.124560
Epub:
Not Epub
Abstract:
Wnt3 proteins are lipidated and glycosylated, secreted signaling molecules that play an im-portant role in zebrafish neural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T. Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.124560.

Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom

Authors:
Sachkova MY, Landau M, Surm JM, Macrander J, Singer S, Reitzel AM, Moran Y
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.121442
Epub:
Not Epub
Abstract:
The sea anemone Nematostella vectensis (Anthozoa, Cnidaria) is a powerful model system for characterizing the evolution of...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Sachkova MY, Landau M, Surm JM, Macrander J, Singer S, Reitzel AM, Moran Y. Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.121442 .

Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication

Authors:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW
Citation:
Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500. PMID: 33269701; PMCID: PMC7735754
Epub:
Not Epub
Abstract:
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: A549
Citation Extract:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW. Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication. Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500. PMID: 33269701; PMCID: PMC7735754.

The role of matrix metalloproteinase-9 (MMP-9) in neurodevelopmental deficits and experience-dependent structural plasticity in Xenopus laevis tadpoles

Authors:
Gore S, James EJ, Huang L-C, Park JJ, Berghella A, Cline HT, Aizenman CD
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.123661
Epub:
Not Epub
Abstract:
Matrix metalloproteinase-9 is a secreted endopeptidase targeting extracellular matrix proteins, creating permissive...
Delivery Method:
electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gore S, James EJ, Huang L-C, Park JJ, Berghella A, Cline HT, Aizenman CD. The role of matrix metalloproteinase-9 (MMP-9) in neurodevelopmental deficits and experience-dependent structural plasticity in Xenopus laevis tadpoles. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.123661 .

Functional characterization of a "plant-like" HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis

Authors:
Tripathi AM, Fridrich A, Lewandowska M, Moran Y
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.31.126003
Epub:
Not Epub
Abstract:
While the biogenesis of microRNAs (miRNAs) in both animals and plants depends on Dicer, a conserved RNAse III enzyme, its...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Tripathi AM, Fridrich A, Lewandowska M, Moran Y. Functional characterization of a "plant-like" HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.31.126003.

Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes

Authors:
Tong S-K, Lee H-L, Lee Y-C, Wu L-C, Tsou Y-L, Lu S-W, Shih S-W, Hwang P-P, Chou M-Y
Citation:
Int J Mol Sci. 2020;21(11):9357. doi:10.3390/ijms21113957
Epub:
Not Epub
Abstract:
Arginine vasopressin (Avp) is a conserved pleiotropic hormone that is known to regulate both water reabsorption and ion balance...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tong S-K, Lee H-L, Lee Y-C, Wu L-C, Tsou Y-L, Lu S-W, Shih S-W, Hwang P-P, Chou M-Y. Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes. Int J Mol Sci. 2020;21(11):9357. doi:10.3390/ijms21113957.

Ethanol and cannabinoids regulate zebrafish GABAergic neuron development and behavior in a sonic hedgehog and fibroblast growth factor dependent mechanism

Authors:
Boa-Amponsem O, Zhang C, Burton D, Williams KP, Cole GJ
Citation:
Alcohol Clin Exp Res. 2020 May 29. doi: 10.1111/acer.14383. Online ahead of print
Epub:
Not Epub
Abstract:
Background: Ethanol has diverse effects on nervous system development, which includes development and survival of GABAergic...
Organism or Cell Type:
zebrafish
Citation Extract:
Boa-Amponsem O, Zhang C, Burton D, Williams KP, Cole GJ . Ethanol and cannabinoids regulate zebrafish GABAergic neuron development and behavior in a sonic hedgehog and fibroblast growth factor dependent mechanism. Alcohol Clin Exp Res. 2020 May 29. doi: 10.1111/acer.14383. Online ahead of print.

The Axenfeld-Rieger syndrome gene FOXC1 contributes to left-right patterning

Authors:
Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson A-M, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.120915
Epub:
Not Epub
Abstract:
Normal body situs requires precise spatiotemporal expression of the Nodal-Lefty-Pitx2 cascade in the lateral plate mesoderm....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson A-M, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ. The Axenfeld-Rieger syndrome gene FOXC1 contributes to left-right patterning. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.120915 .

Neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and brain size in Xenopus embryos

Authors:
Willsey HR, Xu Y, Everitt A, Dea J, Exner CRT, Willsey AJ, State MW, Harland RM
Citation:
Development. 2020:dev.189290 {Epub ahead of print] doi: 10.1242/dev.189290
Epub:
Yes
Abstract:
DYRK1A (dual specificity tyrosine-(Y)-phosphorylation-regulated kinase 1 A) is a high confidence autism risk gene that encodes...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Willsey HR, Xu Y, Everitt A, Dea J, Exner CRT, Willsey AJ, State MW, Harland RM. Neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and brain size in Xenopus embryos. Development. 2020:dev.189290 {Epub ahead of print] doi: 10.1242/dev.189290.

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