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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Antisense-Based Progerin Downregulation in HGPS-Like Patients’ Cells
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Citation:
Cells, 2016;5(3):31. doi:10.3390/cells5030031 Epub:
Not Epub Abstract:
Progeroid laminopathies, including Hutchinson-Gilford Progeria Syndrome (HGPS, OMIM #176670), are premature and accelerated... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary human dermal fibroblasts Citation Extract: Harhouri K, Navarro C, Baquerre C, Da Silva N, Bartoli C, Casey F, Mawuse GK, Doubaj Y, Lévy N, De Sandre-Giovannoli A. Antisense-Based Progerin Downregulation in HGPS-Like Patients’ Cells. Cells, 2016;5(3):31. doi:10.3390/cells5030031. |
The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis
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Citation:
Biochem Biophys Res Commun. 2016 Jul 7. pii: S0006-291X(16)31136-6. doi: 10.1016/j.bbrc.2016.07.021. [Epub ahead of print] Epub:
Yes Abstract:
Alternative splicing is a major mechanism regulating pattern of gene expression through the production of multiple mRNAs from a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Lee SH, Lee HK, Kim C, Kim YK, Ismail T, Jeong Y, Park K, Park JW, Kwon OS, Kang BS, Lee DS, Park MJ, Park DS, Lee HS. The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis. Biochem Biophys Res Commun. 2016 Jul 7. pii: S0006-291X(16)31136-6. doi: 10.1016/j.bbrc.2016.07.021. [Epub ahead of print]. |
Expression and knockdown of zebrafish folliculin suggests requirement for embryonic brain morphogenesis
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Citation:
BMC Dev Biol. 2016 Jul 8;16(1):23 Epub:
Not Epub Abstract:
BACKGROUND: Birt-Hogg-Dubé syndrome (BHD) is a dominantly inherited familial cancer syndrome characterised by the development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kenyon EJ, Luijten MN, Gill H, Li N, Rawlings M, Bull JC, Hadzhiev Y, van Steensel MA, Maher E, Mueller F. Expression and knockdown of zebrafish folliculin suggests requirement for embryonic brain morphogenesis. BMC Dev Biol. 2016 Jul 8;16(1):23. |
Early-life glucocorticoids programme behaviour and metabolism in adulthood in zebrafish
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Citation:
J Endocrinol. 2016 Jul;230(1):125-42. doi: 10.1530/JOE-15-0376 Epub:
Not Epub Abstract:
Glucocorticoids (GCs) in utero influence embryonic development with consequent programmed effects on adult physiology and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wilson KS, Tucker CS, Al-Dujaili EA, Holmes MC, Hadoke PW, Kenyon CJ, Denvir MA. Early-life glucocorticoids programme behaviour and metabolism in adulthood in zebrafish. J Endocrinol. 2016 Jul;230(1):125-42. doi: 10.1530/JOE-15-0376. |
Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia
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Citation:
Am J Hum Genet. 2016;99(1):174-87 doi:10.1016/j.ajhg.2016.05.028 Epub:
Not Epub Abstract:
Autosomal-dominant tubulo-interstitial kidney disease (ADTKD) encompasses a group of disorders characterized by renal tubular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bolar NA, Golzio C, Živná M, Hayot G, Van Hemelrijk C, Schepers D, Vandeweyer G, Hoischen A, Huyghe JR, Raes A, Matthys E, Sys E, Azou M, Gubler M-C, Praet M, Van Camp G, McFadden K, Pediaditakis I, Přistoupilová A, Hodaňová K, Vyleťal P, Hartmannová H, Stránecký V, Hůlková H, Barešová V, Jedličková I, Sovová J, Hnízda A, Kidd K, Bleyer AJ, Spong RS, Vande Walle J, Mortier G, Brunner H, Van Laer L, Kmoch S, Katsanis N, Loeys BL. Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia. Am J Hum Genet. 2016;99(1):174-87 doi:10.1016/j.ajhg.2016.05.028. |
Wars2 is a determinant of angiogenesis
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Citation:
Nat Comm. 2016;7:12061. doi:10.1038/ncomms12061 Epub:
Not Epub Abstract:
Coronary flow (CF) measured ex vivo is largely determined by capillary density that reflects angiogenic vessel formation in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang M, Sips P, Khin E, Rotival M, Sun X, Ahmed R, Widjaja AA, Schafer S, Yusoff P, Choksi PK, Ko NSJ, Singh MK, Epstein D, Guan Y, Houštěk J, Mracek T, Nuskova H, Mikell B, Tan J, Pesce F, Kolar F, Bottolo L, Mancini M, Hubner N, Pravenec M, Petretto E, MacRae C, Cook SA. Wars2 is a determinant of angiogenesis. Nat Comm. 2016;7:12061. doi:10.1038/ncomms12061. |
Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation
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Citation:
Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.036 Epub:
Yes Abstract:
During metazoan development, the temporal pattern of morphogen signaling is critical for organizing cell fates in space and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sako K, Pradhan SJ, Barone V, Ingles-Prieto Á, Müller P, Ruprecht V, Čapek D, Galande S, Janovjak H, Heisenberg C-P. Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation. Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.036. |
Dpp/BMP2-4 Mediates Signaling from the D-Quadrant Organizer in a Spiralian Embryo
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Citation:
Curr Biol. 2016;[Epub ahead of print] doi:10.1016/j.cub.2016.05.059 Epub:
Not Epub Abstract:
In some animal groups, the secondary embryonic axis is patterned by a small group of cells, often called an organizer, that... Delivery Method:
microinjection Organism or Cell Type:
Ilyanassa (marine snail) Citation Extract: Lambert JD, Johnson AB, Hudson CN, Chan A. Dpp/BMP2-4 Mediates Signaling from the D-Quadrant Organizer in a Spiralian Embryo. Curr Biol. 2016;[Epub ahead of print] doi:10.1016/j.cub.2016.05.059. |
Knockdown of gene expression by antisense morpholino oligos in preimplantation mouse embryos cultured in vitro
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Citation:
Anal Biochem. 2016;209:41-5. doi:10.1016/j.ab.2016.06.032 Epub:
Yes Abstract:
Knockdown of gene expression by antisense morpholino oligos (MOs) is a simple and effective method for analyzing the roles of... Delivery Method:
Endo-Porter Organism or Cell Type:
preimplantation mouse embryo Citation Extract: Sato Y, Sato S, Kikuchi T, Nonaka A, Kumagaia Y, Sasaki A, Kobayashi M. Knockdown of gene expression by antisense morpholino oligos in preimplantation mouse embryos cultured in vitro. Anal Biochem. 2016;209:41-5. doi:10.1016/j.ab.2016.06.032. |
Fragile X Mental Retardation Protein Is Required to Maintain Visual Conditioning-Induced Behavioral Plasticity by Limiting Local Protein Synthesis
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Citation:
J Neurosci. 2016;36(27):7325-7339. doi:10.1523/JNEUROSCI.4282-15.2016 Epub:
Not Epub Abstract:
Fragile X mental retardation protein (FMRP) is thought to regulate neuronal plasticity by limiting dendritic protein synthesis... Organism or Cell Type:
Xenopus Citation Extract: Liu H-H, Cline HT. Fragile X Mental Retardation Protein Is Required to Maintain Visual Conditioning-Induced Behavioral Plasticity by Limiting Local Protein Synthesis. J Neurosci. 2016;36(27):7325-7339. doi:10.1523/JNEUROSCI.4282-15.2016. |