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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins
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Citation:
Nat Comm. 2016;7:12077 doi:10.1038/ncomms12077 Epub:
Not Epub Abstract:
Inflammasomes are cytosolic molecular platforms that alert the immune system about the presence of infection. Here we report... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tyrkalska SD, Candel S, Angosto D, Gómez-Abellán V, Martín-Sánchez F, García-Moreno D, Zapata-Pérez R, Sánchez-Ferrer A, Sepulcre MP, Pelegrín P, Mulero V. Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins. Nat Comm. 2016;7:12077 doi:10.1038/ncomms12077. |
Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis
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Citation:
Nature. 2016;534:700–4. doi:10.1038/nature18310 Epub:
Not Epub Abstract:
Many organs are composed of complex tissue walls that are structurally organized to optimize organ function. In particular, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Han P, Bloomekatz J, Ren J, Zhang R, Grinstein JD, Zhao L, Burns CG, Burns CE, Anderson RM, Chi NC. Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis. Nature. 2016;534:700–4. doi:10.1038/nature18310. |
Fructose Promotes Uptake and Activity of Oligonucleotides With Different Chemistries in a Context-dependent Manner in mdx Mice
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Citation:
Mol Ther Nucleic Acids. 2016 Jun 28;5(6):e329. doi: 10.1038/mtna.2016.46 Epub:
Not Epub Abstract:
Antisense oligonucleotide (AO)-mediated exon-skipping therapeutics shows great promise in correcting frame-disrupting mutations... Delivery Method:
injection standard oligos and peptide-linked Organism or Cell Type:
mice, mdx Citation Extract: Cao L, Han G, Lin C, Gu B, Gao X, Moulton HM, Seow Y, Yin H. Fructose Promotes Uptake and Activity of Oligonucleotides With Different Chemistries in a Context-dependent Manner in mdx Mice. Mol Ther Nucleic Acids. 2016 Jun 28;5(6):e329. doi: 10.1038/mtna.2016.46. |
Mutations in MYT1, encoding the myelin transcription factor 1, are a rare cause of OAVS
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Citation:
J Med Genet. 2016;[Epub ahead of print] doi:10.1136/jmedgenet-2016-103774 Epub:
Not Epub Abstract:
Background: Oculo-auriculo-vertebral spectrum (OAVS) is a developmental disorder involving first and second branchial arches... Organism or Cell Type:
zebrafish Citation Extract: Lopez E, Berenguer M, Tingaud-Sequeira A, Marlin S, Toutain A, Denoyelle F, Picard A, Charron S, Mathieu G, de Belvalet H, Arveiler B, Babin PJ, Lacombe D, Rooryck C
. Mutations in MYT1, encoding the myelin transcription factor 1, are a rare cause of OAVS. J Med Genet. 2016;[Epub ahead of print] doi:10.1136/jmedgenet-2016-103774. |
TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response
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Citation:
PLoS Pathog. 2016;12(6):e1005699. doi:10.1371/journal.ppat.1005699 Epub:
Not Epub Abstract:
TNFα is a pleiotropic pro-inflammatory cytokine with a key role in the activation of the immune system to fight viral... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Espín-Palazón R, Martínez-López A, Roca FJ, López-Muñoz A, Tyrkalska SD, Candel S, García-Moreno D, Falco A, Meseguer J, Estepa A, Mulero V. TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response. PLoS Pathog. 2016;12(6):e1005699. doi:10.1371/journal.ppat.1005699. |
Memory of cell shape biases stochastic fate decision-making despite mitotic rounding
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Citation:
Nat Comm. 2016;7:11963. doi:10.1038/ncomms11963 Epub:
Not Epub Abstract:
Cell shape influences function, and the current model suggests that such shape effect is transient. However, cells dynamically... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Akanuma T, Chen C, Sato T, Merks RMH, Sato TN. Memory of cell shape biases stochastic fate decision-making despite mitotic rounding. Nat Comm. 2016;7:11963. doi:10.1038/ncomms11963. |
Reprogramming of avian neural crest axial identity and cell fate
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Citation:
Science. 2016 Jun 24;352(6293):1570-3. doi: 10.1126/science.aaf2729 Epub:
Not Epub Abstract:
Neural crest populations along the embryonic body axis of vertebrates differ in developmental potential and fate, so that only... Delivery Method:
injection then electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Simoes-Costa M, Bronner ME. Reprogramming of avian neural crest axial identity and cell fate. Science. 2016 Jun 24;352(6293):1570-3. doi: 10.1126/science.aaf2729. |
N-cadherin relocalization during cardiac trabeculation
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Citation:
Proc Natl Acad Sci U S A. 2016 Jun 23. pii: 201606385. [Epub ahead of print] Epub:
Yes Abstract:
During cardiac trabeculation, cardiomyocytes delaminate from the outermost (compact) layer to form complex muscular structures... Organism or Cell Type:
zebrafish Citation Extract: Cherian AV, Fukuda R, Augustine SM, Maischein HM, Stainier DY. N-cadherin relocalization during cardiac trabeculation. Proc Natl Acad Sci U S A. 2016 Jun 23. pii: 201606385. [Epub ahead of print]. |
Secreted frizzled-related protein 2 (sFRP2) redirects non-canonical Wnt signaling from Fz7 to Ror2 during vertebrate gastrulation
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Citation:
J Biol Chem. 2016 Apr 29. pii: jbc.M116.733766. [Epub ahead of print] Epub:
Not Epub Abstract:
Convergent extension (CE) movements during vertebrate gastrulation require a balanced activity of non-canonical Wnt signaling... Citation Extract: Brinkmann EM, Mattes B, Kumar R, Hagemann AI, Gradl D, Scholpp S, Steinbeisser H, Kaufmann LT, Ozbek S. Secreted frizzled-related protein 2 (sFRP2) redirects non-canonical Wnt signaling from Fz7 to Ror2 during vertebrate gastrulation. J Biol Chem. 2016 Apr 29. pii: jbc.M116.733766. [Epub ahead of print]. |
A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification
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Citation:
Cell Rep. 2016 Jun 15. pii: S2211-1247(16)30658-1. doi: 10.1016/j.celrep.2016.05.060. [Epub ahead of print] Epub:
Yes Abstract:
Organogenesis of the trachea and lungs requires a complex series of mesoderm-endoderm interactions mediated by WNT, BMP,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM
. A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification. Cell Rep. 2016 Jun 15. pii: S2211-1247(16)30658-1. doi: 10.1016/j.celrep.2016.05.060. [Epub ahead of print]. |