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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Rx3 and Shh direct anisotropic growth and specification in the zebrafish tuberal/anterior hypothalamus

Authors:
Muthu V, Eachus H, Ellis P, Brown S, Placzek M
Citation:
Development. 2016 Jun 17. pii: dev.138305. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In the developing brain, growth and differentiation are intimately linked. Here we show that in the zebrafish embryo, the...
Link:
http://dev.biologists.org/content/early/2016/06/10/dev.138305.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Muthu V, Eachus H, Ellis P, Brown S, Placzek M. Rx3 and Shh direct anisotropic growth and specification in the zebrafish tuberal/anterior hypothalamus. Development. 2016 Jun 17. pii: dev.138305. [Epub ahead of print].

Two novel EIF2S3 mutations associated with syndromic intellectual disability with severe microcephaly, growth retardation, and epilepsy

Authors:
Moortgat S, Désir J, Benoit V, Boulanger S, Pendeville H, Nassogne MC, Lederer D, Maystadt I
Citation:
Am J Med Genet A. 2016 Jun 22. doi: 10.1002/ajmg.a.37792. [Epub ahead of print]
Epub:
Not Epub
Abstract:
X-chromosome exome sequencing was performed to identify the genetic cause of syndromic intellectual disability in two unrelated...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.37792/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Moortgat S, Désir J, Benoit V, Boulanger S, Pendeville H, Nassogne MC, Lederer D, Maystadt I. Two novel EIF2S3 mutations associated with syndromic intellectual disability with severe microcephaly, growth retardation, and epilepsy. Am J Med Genet A. 2016 Jun 22. doi: 10.1002/ajmg.a.37792. [Epub ahead of print].

Dazl is a critical player for primordial germ cell formation in medaka

Authors:
Li M, Zhu F, Li Z, Hong N, Hong Y
Citation:
Sci Rep. 2016 Jun 22;6:28317. doi: 10.1038/srep28317
Epub:
Not Epub
Abstract:
The DAZ family genes boule, daz and dazl have conserved functions in primordial germ cell (PGC) migration, germ stem cell...
Link:
http://www.nature.com/articles/srep28317
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Li M, Zhu F, Li Z, Hong N, Hong Y. Dazl is a critical player for primordial germ cell formation in medaka. Sci Rep. 2016 Jun 22;6:28317. doi: 10.1038/srep28317.

Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease)

Authors:
Wager K, Zdebik AA, Fu S, Cooper JD, Harvey RJ, Russell C
Citation:
PLoS One. 2016 Jun 21;11(6):e0157365. doi: 10.1371/journal.pone.0157365. eCollection 2016
Epub:
Not Epub
Abstract:
The neuronal ceroid lipofuscinoses are a group of lysosomal storage disorders that comprise the most common, genetically...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157365
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wager K, Zdebik AA, Fu S, Cooper JD, Harvey RJ, Russell C. Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease). PLoS One. 2016 Jun 21;11(6):e0157365. doi: 10.1371/journal.pone.0157365. eCollection 2016.

Zebrafish cyclin Dx is required for development of motor neuron progenitors, and its expression is regulated by hypoxia-inducible factor 2α

Authors:
Lien HW, Yuan RY, Chou CM, Chen YC, Hung CC, Hu CH, Hwang SP, Hwang PP, Shen CN, Chen CL, Cheng CH, Huang CJ
Citation:
Sci Rep. 2016 Jun 21;6:28297. doi: 10.1038/srep28297
Epub:
Not Epub
Abstract:
Cyclins play a central role in cell-cycle regulation; in mammals, the D family of cyclins consists of cyclin D1, D2, and D3. In...
Link:
http://www.nature.com/articles/srep28297
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lien HW, Yuan RY, Chou CM, Chen YC, Hung CC, Hu CH, Hwang SP, Hwang PP, Shen CN, Chen CL, Cheng CH, Huang CJ. Zebrafish cyclin Dx is required for development of motor neuron progenitors, and its expression is regulated by hypoxia-inducible factor 2α. Sci Rep. 2016 Jun 21;6:28297. doi: 10.1038/srep28297.

IFT46 plays crucial roles in craniofacial and cilia development

Authors:
Park I, Lee HK, Kim C, Ismail T, Kim YK, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Park MJ, Choi SC, Lee HS
Citation:
Biochem Biophys Res Commun. 2016 Jun 16. pii: S0006-291X(16)31001-4. doi: 10.1016/j.bbrc.2016.06.083. [Epub ahead of print]
Epub:
Yes
Abstract:
The intraflagellar transport (IFT) system is essential for bidirectional movement of ciliary components from the basal body to...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X16310014
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park I, Lee HK, Kim C, Ismail T, Kim YK, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Park MJ, Choi SC, Lee HS. IFT46 plays crucial roles in craniofacial and cilia development. Biochem Biophys Res Commun. 2016 Jun 16. pii: S0006-291X(16)31001-4. doi: 10.1016/j.bbrc.2016.06.083. [Epub ahead of print].

Beneficial roles of melanoma cell adhesion molecule in spinal cord transection recovery in adult zebrafish

Authors:
Liu CJ, Xie L, Cui C, Chu M, De Zhao H, Yao L, Li YH, Schachner M, Shen YQ
Citation:
J Neurochem. 2016 Jun 18. doi: 10.1111/jnc.13707. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Melanoma cell adhesion molecule (MCAM) is a multifunctional protein involved in miscellaneous processes, including development...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/jnc.13707/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Liu CJ, Xie L, Cui C, Chu M, De Zhao H, Yao L, Li YH, Schachner M, Shen YQ. Beneficial roles of melanoma cell adhesion molecule in spinal cord transection recovery in adult zebrafish. J Neurochem. 2016 Jun 18. doi: 10.1111/jnc.13707. [Epub ahead of print].

Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity

Authors:
Eichner R, Heider M, Fernández-Sáiz V, van Bebber F, Garz AK, Lemeer S, Rudelius M, Targosz BS, Jacobs L, Knorn AM, Slawska J, Platzbecker U, Germing U, Langer C, Knop S, Einsele H, Peschel C, Haass C, Keller U, Schmid B, Götze KS, Kuster B, Bassermann F
Citation:
Nat Med. 2016 Jun 13. doi: 10.1038/nm.4128. [Epub ahead of print]
Epub:
Yes
Abstract:
Immunomodulatory drugs (IMiDs), such as thalidomide and its derivatives lenalidomide and pomalidomide, are key treatment...
Link:
http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.4128.html
Organism or Cell Type:
zebrafish
Citation Extract:
Eichner R, Heider M, Fernández-Sáiz V, van Bebber F, Garz AK, Lemeer S, Rudelius M, Targosz BS, Jacobs L, Knorn AM, Slawska J, Platzbecker U, Germing U, Langer C, Knop S, Einsele H, Peschel C, Haass C, Keller U, Schmid B, Götze KS, Kuster B, Bassermann F. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016 Jun 13. doi: 10.1038/nm.4128. [Epub ahead of print].

Epigenetic activation of Sox2 gene in the developing vertebrate neural plate

Authors:
Bouzas SO, Marini MS, Torres Zelada E, Buzzi AL, Morales Vicente DA, Strobl-Mazzulla PH
Citation:
Mol Biol Cell. 2016 Jun 15;27(12):1921-7. doi: 10.1091/mbc.E16-01-0042. Epub 2016 Apr 20
Epub:
Not Epub
Abstract:
One of the earliest manifestations of neural induction is onset of expression of the neural marker Sox2, mediated by the...
Link:
http://www.molbiolcell.org/content/27/12/1921.abstract
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Bouzas SO, Marini MS, Torres Zelada E, Buzzi AL, Morales Vicente DA, Strobl-Mazzulla PH. Epigenetic activation of Sox2 gene in the developing vertebrate neural plate. Mol Biol Cell. 2016 Jun 15;27(12):1921-7. doi: 10.1091/mbc.E16-01-0042. Epub 2016 Apr 20.

Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells

Authors:
Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T
Citation:
Clin Cancer Res. 2016 Dec 1;22(23):5915-5928. doi: 10.1158/1078-0432.CCR-15-1739. Epub 2016 Jun 15. PMID: 27307595
Epub:
Yes
Abstract:
Purpose: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive human T-cell malignancy induced by human T-lymphotrophic virus-...
Link:
https://aacrjournals.org/clincancerres/article/22/23/5915/122959/Dysregulation-of-c-Myb-Pathway-by-Aberrant
Organism or Cell Type:
cell culture: adult T-cell leukemia/lymphoma cells
Citation Extract:
Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T. Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells. Clin Cancer Res. 2016 Dec 1;22(23):5915-5928. doi: 10.1158/1078-0432.CCR-15-1739. Epub 2016 Jun 15. PMID: 27307595.

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