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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo

Authors:
Oda H, Sato Y, Kawashima SA, Fujiwara Y, Pálfy M, Wu E, Vastenhouw NL, Kanai M, Kimura H
Citation:
Biol Open. 2023 May 15;12(5):bio059783. doi: 10.1242/bio.059783. Epub 2023 May 17
Epub:
Not Epub
Abstract:
In the cytoplasm, filamentous actin (F-actin) plays a critical role in cell regulation, including cell migration, stress fiber...
Link:
https://journals.biologists.com/bio/article/12/5/bio059783/310414/Actin-filaments-accumulated-in-the-nucleus-remain
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oda H, Sato Y, Kawashima SA, Fujiwara Y, Pálfy M, Wu E, Vastenhouw NL, Kanai M, Kimura H. Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo. Biol Open. 2023 May 15;12(5):bio059783. doi: 10.1242/bio.059783. Epub 2023 May 17.

Functional characterization of stap2b in zebrafish vascular development

Authors:
Wang YS, Chen YT, Wu CY
Citation:
FASEB J. 2023 Jul;37(7):e23053. doi: 10.1096/fj.202201314RRR
Epub:
Not Epub
Abstract:
The genetic control and signaling pathways of vascular development are not comprehensively understood. Transcription factors...
Link:
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201314RRR
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang YS, Chen YT, Wu CY. Functional characterization of stap2b in zebrafish vascular development. FASEB J. 2023 Jul;37(7):e23053. doi: 10.1096/fj.202201314RRR.

A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription

Authors:
Estell C, Davidson L, Eaton JD, Kimura H, Gold VAM, West S
Citation:
Mol Cell. 2023 Jul 6;83(13):2222-2239.e5. doi: 10.1016/j.molcel.2023.05.029. Epub 2023 Jun 16.
Epub:
Yes
Abstract:
The transcriptional termination of unstable non-coding RNAs (ncRNAs) is poorly understood compared to coding transcripts. We...
Link:
https://www.sciencedirect.com/science/article/pii/S1097276523003854
Delivery Method:
electroporation
Organism or Cell Type:
cell culture
Citation Extract:
Estell C, Davidson L, Eaton JD, Kimura H, Gold VAM, West S. A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription. Mol Cell. 2023 Jul 6;83(13):2222-2239.e5. doi: 10.1016/j.molcel.2023.05.029. Epub 2023 Jun 16. .

Recruitment of transcription factor ETS1 to activated accessible regions promotes the transcriptional program of cilia genes

Authors:
Zhang D, Zhang C, Zhu Y, Xie H, Yue C, Li M, Wei W, Peng Y, Yin G, Guo Y, Guan Y
Citation:
Nucleic Acids Res. 2023 Jun 16:gkad506. doi: 10.1093/nar/gkad506. Online ahead of print
Epub:
Not Epub
Abstract:
Defects in cilia genes, which are critical for cilia formation and function, can cause complicated ciliopathy syndromes...
Link:
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad506/7199338
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang D, Zhang C, Zhu Y, Xie H, Yue C, Li M, Wei W, Peng Y, Yin G, Guo Y, Guan Y. Recruitment of transcription factor ETS1 to activated accessible regions promotes the transcriptional program of cilia genes. Nucleic Acids Res. 2023 Jun 16:gkad506. doi: 10.1093/nar/gkad506. Online ahead of print.

Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals

Authors:
Zhao Y, Wang H, He T, Ma B, Chen G, Tzeng C
Citation:
J Cell Commun Signal. 2023 Jun 20. doi: 10.1007/s12079-023-00775-6. Online ahead of print
Epub:
Yes
Abstract:
Liver fibrosis is an aberrant wound healing response to tissue injury characterized by excessive extracellular matrix...
Link:
https://link.springer.com/article/10.1007/s12079-023-00775-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Y, Wang H, He T, Ma B, Chen G, Tzeng C. Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals. J Cell Commun Signal. 2023 Jun 20. doi: 10.1007/s12079-023-00775-6. Online ahead of print.

A Role for Microsomal Glutathione Transferase 1 in Melanin Biosynthesis and Melanoma Progression

Authors:
Zhang J, Ye ZW, Bräutigam L, Chakraborty P, Luo Z, Culpepper J, Aslam M, Zhang L, Johansson K, Haeggström JZ, Xu J, Olsson M, Townsend DM, Mehrotra S, Morgenstern R, Tew KD
Citation:
J Biol Chem. 2023 Jun 13:104920. doi:10.1016/j.jbc.2023.104920. Online ahead of print
Epub:
Not Epub
Abstract:
Recent advancements in the treatment of melanoma are encouraging, but there remains a need to identify additional therapeutic...
Link:
https://www.sciencedirect.com/science/article/pii/S0021925823019488
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang J, Ye ZW, Bräutigam L, Chakraborty P, Luo Z, Culpepper J, Aslam M, Zhang L, Johansson K, Haeggström JZ, Xu J, Olsson M, Townsend DM, Mehrotra S, Morgenstern R, Tew KD. A Role for Microsomal Glutathione Transferase 1 in Melanin Biosynthesis and Melanoma Progression. J Biol Chem. 2023 Jun 13:104920. doi:10.1016/j.jbc.2023.104920. Online ahead of print.

Macrophage Migration Inhibitory Factor on Apoptotic Extracellular Vesicles Regulates Compensatory Proliferation

Authors:
Essien SA, Ahuja I, Eisenhoffer GT
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.06.14.544889
Epub:
Not Epub
Abstract:
Apoptotic cells can signal to neighboring cells to stimulate proliferation and compensate for cell loss to maintain tissue...
Link:
https://www.biorxiv.org/content/10.1101/2023.06.14.544889v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Essien SA, Ahuja I, Eisenhoffer GT. Macrophage Migration Inhibitory Factor on Apoptotic Extracellular Vesicles Regulates Compensatory Proliferation. bioRxiv. 2023;[preprint] doi:10.1101/2023.06.14.544889 .

Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemia

Authors:
Chen C, Qin Y, Xu Y, Wang X, Lei W, Shen X, Lixun Chen, Wang L, Gong J, Wang Y, Hu S, Liu D
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.01.23.525218
Epub:
Not Epub
Abstract:
Background: In patients with diabetic microvascular complications, decreased perfusion or vascular occlusion, caused by reduced...
Link:
https://www.biorxiv.org/content/10.1101/2023.01.23.525218v2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen C, Qin Y, Xu Y, Wang X, Lei W, Shen X, Lixun Chen, Wang L, Gong J, Wang Y, Hu S, Liu D. Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemia. bioRxiv. 2023;[preprint] doi:10.1101/2023.01.23.525218 .

NANOG is required to establish the competence for germ-layer differentiation in the basal tetrapod axolotl

Authors:
Simpson LA, Crowley D, Forey T, Acosta H, Ferjentsik Z, Chatfield J, Payne A, Simpson BS, Redwood C, Dixon JE, Holmes N, Sang F, Alberio R, Loose M, Johnson AD
Citation:
PLoS Biol. 2023;21(6):e3002121. doi:10.1371/journal.pbio.3002121
Epub:
Not Epub
Abstract:
Pluripotency defines the unlimited potential of individual cells of vertebrate embryos, from which all adult somatic cells and...
Link:
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002121
Delivery Method:
microinjection
Organism or Cell Type:
Ambystoma mexicanum (Axolotl)
Citation Extract:
Simpson LA, Crowley D, Forey T, Acosta H, Ferjentsik Z, Chatfield J, Payne A, Simpson BS, Redwood C, Dixon JE, Holmes N, Sang F, Alberio R, Loose M, Johnson AD. NANOG is required to establish the competence for germ-layer differentiation in the basal tetrapod axolotl. PLoS Biol. 2023;21(6):e3002121. doi:10.1371/journal.pbio.3002121.

In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss

Authors:
Vijayakumar S, DiGuiseppi JA, Dabestani PJ, Ryan WG, Quevedo RV, Li Y, Diers J, Tu S, Fleegel J, Nguyen C, Rhoda LM, Imami AS, Hamoud AA, Lovas S, McCullumsmith RE, Zallocchi M, Zuo J
Citation:
Sci Adv. 2024 Jun 21;10(25):eadk2299. doi: 10.1126/sciadv.adk2299. Epub 2024 Jun 19. PMID: 38896614; PMCID: PMC11186505.
Epub:
Not Epub
Abstract:
Noise-induced hearing loss (NIHL) is a common sensorineural hearing impairment that lacks U.S. Food and Drug Administration–...
Link:
https://www.science.org/doi/pdf/10.1126/sciadv.adk2299
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vijayakumar S, DiGuiseppi JA, Dabestani PJ, Ryan WG, Quevedo RV, Li Y, Diers J, Tu S, Fleegel J, Nguyen C, Rhoda LM, Imami AS, Hamoud AA, Lovas S, McCullumsmith RE, Zallocchi M, Zuo J. In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss. Sci Adv. 2024 Jun 21;10(25):eadk2299. doi: 10.1126/sciadv.adk2299. Epub 2024 Jun 19. PMID: 38896614; PMCID: PMC11186505..

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