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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation
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Citation:
Biochem Biophys Res Commun. 2023 Jun 19;673:9-15. doi: 10.1016/j.bbrc.2023.06.058. Online ahead of print Epub:
Not Epub Abstract:
Nephronophthisis (NPH), an autosomal recessive ciliopathy, results from mutations in more than 20 different genes (NPHPs).... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang H, Zaiser F, Eckert P, Ruf J, Kayser N, Veenstra AC, Müller M, Haas R, Walz G, Yakulov TA. Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation. Biochem Biophys Res Commun. 2023 Jun 19;673:9-15. doi: 10.1016/j.bbrc.2023.06.058. Online ahead of print. |
Etv5a suppresses neural progenitor cell proliferation by inhibiting sox2 transcription
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Citation:
Stem Cells Dev. 2023 Jun 26. doi: 10.1089/scd.2023.0005. Online ahead of print Epub:
Yes Abstract:
Neural progenitor cells are self-renewable, proliferative, and multipotent cell populations that generate diverse types of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shih HY, Chen HY, Huang YC, Yeh TH, Chen YC, Cheng YC. Etv5a suppresses neural progenitor cell proliferation by inhibiting sox2 transcription. Stem Cells Dev. 2023 Jun 26. doi: 10.1089/scd.2023.0005. Online ahead of print. |
Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.05.24.542079 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle degenerating disease caused by dystrophin deficiency.... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: healthy and DMD myotubes Citation Extract: Hariharan S, Lorintiu O, Lee C-C, Duchemin-Pelletier E, Li X, Healy A, Doyonnas R, Selig L, Poydenot P, Ventre E, Weston A, Owens J, Christoforou N. Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients. bioRxiv. 2023;[preprint] doi:10.1101/2023.05.24.542079. |
A median fin derived from the lateral plate mesoderm and the origin of paired fins
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Citation:
Nature. 2023 Jun;618(7965):543-549. doi:10.1038/s41586-023-06100-w. Epub 2023 May 24 Epub:
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The development of paired appendages was a key innovation during evolution and facilitated the aquatic to terrestrial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tzung KW, Lalonde RL, Prummel KD, Mahabaleshwar H, Moran HR, Stundl J, Cass AN, Le Y, Lea R, Dorey K, Tomecka MJ, Zhang C, Brombacher EC, White WT, Roehl HH, Tulenko FJ, Winkler C, Currie PD, Amaya E, Davis MC, Bronner ME, Mosimann C, Carney TJ. A median fin derived from the lateral plate mesoderm and the origin of paired fins . Nature. 2023 Jun;618(7965):543-549. doi:10.1038/s41586-023-06100-w. Epub 2023 May 24. |
Cerebellar granular neuron progenitors exit their germinative niche via Barhl1 mediated silencing of T-Cell Factor transcriptional activity
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.05.25.542248 Epub:
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T-Cell Factors (TCFs) are the main transcriptional effectors of Wnt/β-catenin signaling. TCF responsiveness is a hallmark of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis Citation Extract: Bou-Rouphael J, Doulazmi M, Eschstruth A, Abdou A, Durand BC. Cerebellar granular neuron progenitors exit their germinative niche via Barhl1 mediated silencing of T-Cell Factor transcriptional activity. bioRxiv. 2023;[preprint] doi:10.1101/2023.05.25.542248. |
Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction
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Citation:
Nat Commun. 2023 May 24;14(1):2868. doi: 10.1038/s41467-023-38526-1 Epub:
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Gene-environment interactions are believed to play a role in multifactorial phenotypes, although poorly described... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Alvizi L, Nani D, Brito LA, Kobayashi GS, Passos-Bueno MR, Mayor R. Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction. Nat Commun. 2023 May 24;14(1):2868. doi: 10.1038/s41467-023-38526-1. |
Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network
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Citation:
Elife. 2023 May 25;12:e85594. doi: 10.7554/eLife.85594 Epub:
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Genetic studies in human and mice have established a dual role for Vsx genes in retina development: an early function in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Letelier J, Buono L, Almuedo-Castillo M, Zang J, Mounieres C, González-Díaz S, Polvillo R, Sanabria-Reinoso E, Corbacho J, Sousa-Ortega A, Diez Del Corral R, Neuhauss SCF, Martínez-Morales JR. Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network. Elife. 2023 May 25;12:e85594. doi: 10.7554/eLife.85594. |
Identification of an α-l-iduronidase (IDUA) M1T mutation in a Chinese family with autosomal recessive mucopolysaccharidosis I
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Citation:
Ann N Y Acad Sci. 2023 Jun 22. doi: 10.1111/nyas.15016. Online ahead of print Epub:
Yes Abstract:
Mucopolysaccharidoses (MPS) are a group of rare congenital metabolic disorders caused by the deficiency or low activity of... Organism or Cell Type:
zebrafish Citation Extract: Liu D, Jiang Z, Deng L, Li H, Jiang H. Identification of an α-l-iduronidase (IDUA) M1T mutation in a Chinese family with autosomal recessive mucopolysaccharidosis I. Ann N Y Acad Sci. 2023 Jun 22. doi: 10.1111/nyas.15016. Online ahead of print. |
DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1
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Citation:
Mol Ther Nucleic Acids. 2023 May 16;32:937-948. doi: 10.1016/j.omtn.2023.05.017. eCollection 2023 Jun 13 Epub:
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Dominant missense mutations in DNAJB6, a co-chaperone of HSP70, cause limb girdle muscular dystrophy (LGMD) D1. No treatments... Delivery Method:
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Cell culture: murine primary myotubes, human primary LGMDD1 myoblasts; mice Citation Extract: Findlay AR, Paing MM, Daw JA, Haller M, Bengoechea R, Pittman SK, Li S, Wang F, Miller TM, True HL, Chou TF, Weihl CC. DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1. Mol Ther Nucleic Acids. 2023 May 16;32:937-948. doi: 10.1016/j.omtn.2023.05.017. eCollection 2023 Jun 13. |
Cryo-EM structure of the Mon1-Ccz1-RMC1 complex reveals molecular basis of metazoan RAB7A activation
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Citation:
Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2301725120. doi: 10.1073/pnas.2301725120. Epub 2023 May 22 Epub:
Not Epub Abstract:
Understanding of the evolution of metazoans from their unicellular ancestors is a fundamental question in biology. In contrast... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yong X, Jia G, Liu Z, Zhou C, Yi J, Tang Y, Chen L, Chen L, Wang Y, Sun Q, Billadeau DD, Su Z, Jia D. Cryo-EM structure of the Mon1-Ccz1-RMC1 complex reveals molecular basis of metazoan RAB7A activation. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2301725120. doi: 10.1073/pnas.2301725120. Epub 2023 May 22. |