You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Development of small fluorescent probes for the analysis of autophagy kinetics

Authors:
Sakurai HT, Iwashita H, Arakawa S, Yikelamu A, Kusaba M, Kofuji S, Nishina H, Ishiyama M, Ueno Y, Shimizu S
Citation:
iScience. 2023 Jun 28;26(7):107218. doi: 10.1016/j.isci.2023.107218. eCollection 2023 Jul 21
Epub:
Not Epub
Abstract:
Autophagy is a dynamic process that degrades subcellular constituents, and its activity is measured by autophagic flux. The...
Link:
https://www.cell.com/iscience/fulltext/S2589-0042(23)01295-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sakurai HT, Iwashita H, Arakawa S, Yikelamu A, Kusaba M, Kofuji S, Nishina H, Ishiyama M, Ueno Y, Shimizu S. Development of small fluorescent probes for the analysis of autophagy kinetics. iScience. 2023 Jun 28;26(7):107218. doi: 10.1016/j.isci.2023.107218. eCollection 2023 Jul 21.

lmo4a Contributes to Zebrafish Inner Ear and Vestibular Development via Regulation of the Bmp Pathway

Authors:
Sun L, Ping L, Gao R, Zhang B, Chen X
Citation:
Genes. 2023;14:1371. doi:10.3390/genes14071371
Epub:
Not Epub
Abstract:
Background: In vertebrates, the development of the inner ear is a delicate process, whereas its relating molecular pathways are...
Link:
https://www.mdpi.com/2073-4425/14/7/1371
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun L, Ping L, Gao R, Zhang B, Chen X. lmo4a Contributes to Zebrafish Inner Ear and Vestibular Development via Regulation of the Bmp Pathway. Genes. 2023;14:1371. doi:10.3390/genes14071371.

Upf3a but not Upf1 mediates the genetic compensation response induced by leg1 deleterious mutations in an H3K4me3-independent manner

Authors:
Xie A, Ma Z, Wang J, Zhang Y, Chen Y, Yang C, Chen J, Peng J
Citation:
Cell Discov. 2023 Jun 27;9(1):63. doi: 10.1038/s41421-023-00550-2
Epub:
Not Epub
Abstract:
Genetic compensation responses (GCRs) can be induced by deleterious mutations in living organisms in order to maintain genetic...
Link:
https://www.nature.com/articles/s41421-023-00550-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xie A, Ma Z, Wang J, Zhang Y, Chen Y, Yang C, Chen J, Peng J. Upf3a but not Upf1 mediates the genetic compensation response induced by leg1 deleterious mutations in an H3K4me3-independent manner. Cell Discov. 2023 Jun 27;9(1):63. doi: 10.1038/s41421-023-00550-2.

Deep intronic founder mutations identified in the ERCC4/XPF gene are potential therapeutic targets for a high-frequency form of xeroderma pigmentosum

Authors:
Senju C, Nakazawa Y, Oso T, Shimada M, Kato K, Matsuse M, Tsujimoto M, Masaki T, Miyazaki Y, Fukushima S, Tateishi S, Utani A, Murota H, Tanaka K, Mitsutake N, Moriwaki S, Nishigori C, Ogi T
Citation:
Proc Natl Acad Sci U S A. 2023 Jul 4;120(27):e2217423120. doi: 10.1073/pnas.2217423120. Epub 2023 Jun 26
Epub:
Not Epub
Abstract:
Xeroderma pigmentosum (XP) is a genodermatosis defined by cutaneous photosensitivity with an increased risk of skin tumors...
Link:
https://www.pnas.org/doi/10.1073/pnas.2217423120
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: XP43NG, XP3YO
Citation Extract:
Senju C, Nakazawa Y, Oso T, Shimada M, Kato K, Matsuse M, Tsujimoto M, Masaki T, Miyazaki Y, Fukushima S, Tateishi S, Utani A, Murota H, Tanaka K, Mitsutake N, Moriwaki S, Nishigori C, Ogi T. Deep intronic founder mutations identified in the ERCC4/XPF gene are potential therapeutic targets for a high-frequency form of xeroderma pigmentosum. Proc Natl Acad Sci U S A. 2023 Jul 4;120(27):e2217423120. doi: 10.1073/pnas.2217423120. Epub 2023 Jun 26.

Synthesis and Biophysical Studies of High Affinity Morpholino Oligomers Containing G-clamp Analogs

Authors:
Sinha S, Das A, Ghosh A, Kundu J, Egli M, Manoharan M
Citation:
ChemRxiv. 2023:[preprint] doi:10.26434/chemrxiv-2023-fhfbr
Epub:
Not Epub
Abstract:
Synthesis of chlorophosphoramidate morpholino monomers containing tricyclic cytosine analogs phenoxazine, G-clamp, and G8AE-...
Link:
https://chemrxiv.org/engage/chemrxiv/article-details/649ae6c1ba3e99daef1f7404
Citation Extract:
Sinha S, Das A, Ghosh A, Kundu J, Egli M, Manoharan M. Synthesis and Biophysical Studies of High Affinity Morpholino Oligomers Containing G-clamp Analogs. ChemRxiv. 2023:[preprint] doi:10.26434/chemrxiv-2023-fhfbr.

Identification of protein phosphatase 4 catalytic subunit as a Wnt promoting factor in pan-cancer and Xenopus early embryogenesis

Authors:
Wang Y, Han W, Yun S, Han J
Citation:
Sci Rep. 2023 Jun 23;13(1):10240. doi: 10.1038/s41598-023-35719-y
Epub:
Not Epub
Abstract:
Protein Phosphatase 4 Catalytic Subunit (PPP4C) is an evolutionarily conserved protein involved in multiple biological and...
Link:
https://www.nature.com/articles/s41598-023-35719-y
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wang Y, Han W, Yun S, Han J. Identification of protein phosphatase 4 catalytic subunit as a Wnt promoting factor in pan-cancer and Xenopus early embryogenesis. Sci Rep. 2023 Jun 23;13(1):10240. doi: 10.1038/s41598-023-35719-y.

Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation

Authors:
Chen X, Li Y, Xu J, Cui Y, Wu Q, Yin H, Li Y, Gao C, Jiang L, Wang H, Wen Z, Yao Z, Wu Z
Citation:
Elife. 2024 Jun 3;12:RP87434. doi: 10.7554/eLife.87434. PMID: 38829202.
Epub:
Not Epub
Abstract:
Styxl2, a poorly characterized pseudophosphatase, was identified as a transcriptional target of the Jak1-Stat1 pathway during...
Link:
https://elifesciences.org/articles/87434
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Li Y, Xu J, Cui Y, Wu Q, Yin H, Li Y, Gao C, Jiang L, Wang H, Wen Z, Yao Z, Wu Z. Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation. Elife. 2024 Jun 3;12:RP87434. doi: 10.7554/eLife.87434. PMID: 38829202..

UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis

Authors:
Kim J, Kim BY, Lee JS, Jeong YM, Cho HJ, Park E, Kim D, Kim SS, Kim BT, Choi YJ, Won YY, Jin HS, Chung YS, Jeong SY
Citation:
Nat Commun. 2023 Jun 20;14(1):3668. doi: 10.1038/s41467-023-39448-8
Epub:
Not Epub
Abstract:
Osteoporosis is a condition characterized by decreased bone mineral density (BMD) and reduced bone strength, leading to an...
Link:
https://www.nature.com/articles/s41467-023-39448-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim J, Kim BY, Lee JS, Jeong YM, Cho HJ, Park E, Kim D, Kim SS, Kim BT, Choi YJ, Won YY, Jin HS, Chung YS, Jeong SY. UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis. Nat Commun. 2023 Jun 20;14(1):3668. doi: 10.1038/s41467-023-39448-8.

Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport

Authors:
Roca FJ, Whitworth LJ, Prag HA, Murphy MP, Ramakrishnan L
Citation:
Science. 2022 Jun 24;376(6600):eabh2841. doi: 10.1126/science.abh2841. Epub 2022 Jun 24
Epub:
Not Epub
Abstract:
Tumor necrosis factor (TNF) is a critical host resistance factor against tuberculosis. However, excess TNF produces...
Link:
https://www.science.org/doi/10.1126/science.abh2841
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roca FJ, Whitworth LJ, Prag HA, Murphy MP, Ramakrishnan L. Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport. Science. 2022 Jun 24;376(6600):eabh2841. doi: 10.1126/science.abh2841. Epub 2022 Jun 24.

Transmembrane protein 150b attenuates BMP signaling in the Xenopus organizer

Authors:
Keum BR, Yeo I, Koo Y, Han W, Choi SC, Kim GH, Han JK
Citation:
J Cell Physiol. 2023 Jul 12. doi: 10.1002/jcp.31059. Online ahead of print
Epub:
Yes
Abstract:
The vertebrate organizer is a specified embryonic tissue that regulates dorsoventral patterning and axis formation. Although...
Link:
https://onlinelibrary.wiley.com/doi/10.1002/jcp.31059
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Keum BR, Yeo I, Koo Y, Han W, Choi SC, Kim GH, Han JK. Transmembrane protein 150b attenuates BMP signaling in the Xenopus organizer. J Cell Physiol. 2023 Jul 12. doi: 10.1002/jcp.31059. Online ahead of print.

Pages