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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Identification of the Time Period during Which BMP Signaling Regulates Proliferation of Neural Progenitor Cells in Zebrafish
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Citation:
Int J Mol Sci. 2023;24(2):1733. doi:10.3390/ijms24021733 Epub:
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Bone morphogenetic protein (BMP) signaling regulates neural induction, neuronal specification, and neuronal differentiation.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shih H-Y, Chang C-W, Chen Y-C, Cheng Y-C. Identification of the Time Period during Which BMP Signaling Regulates Proliferation of Neural Progenitor Cells in Zebrafish. Int J Mol Sci. 2023;24(2):1733. doi:10.3390/ijms24021733 . |
Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis
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Citation:
Angiogenesis. 2023 Aug;26(3):365-384. doi: 10.1007/s10456-023-09865-w. Epub 2023 Jan 11. PMID: 36631598; PMCID: PMC10328904 Epub:
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The Feline Leukemia Virus Subgroup C Receptor 1a (FLVCR1a) is a transmembrane heme exporter essential for embryonic vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Petrillo S, De Giorgio F, Bertino F, Garello F, Bitonto V, Longo DL, Mercurio S, Ammirata G, Allocco AL, Fiorito V, Chiabrando D, Altruda F, Terreno E, Provero P, Munaron L, Genova T, Nóvoa A, Carlos AR, Cardoso S, Mallo M, Soares MP, Tolosano E. Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis. Angiogenesis. 2023 Aug;26(3):365-384. doi: 10.1007/s10456-023-09865-w. Epub 2023 Jan 11. PMID: 36631598; PMCID: PMC10328904. |
Inducible in vivo genome editing in the sea star Patiria miniata
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.01.09.523328 Epub:
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For centuries, echinoderms, a marine-invertebrate phylum, have fascinated scientists for their developmental and postembryonic... Delivery Method:
microinjection Organism or Cell Type:
Patiria miniata (sea star) Citation Extract: Zueva O, Hinman VF. Inducible in vivo genome editing in the sea star Patiria miniata. bioRxiv. 2023;[preprint] doi:10.1101/2023.01.09.523328. |
Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease
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Citation:
J Am Soc Nephrol. 2022 Aug;33(8):1501-1516. doi: 10.1681/ASN.2022010053. Epub 2022 Jul 14 Epub:
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Background: Mutations of PKD2, which encodes polycystin-2, cause autosomal dominant polycystic kidney disease (ADPKD). The... Link:
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microinjection Organism or Cell Type:
zebrafish Citation Extract: Padhy B, Xie J, Wang R, Lin F, Huang CL. Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol. 2022 Aug;33(8):1501-1516. doi: 10.1681/ASN.2022010053. Epub 2022 Jul 14. |
Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development
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Citation:
Front Cell Dev Biol. 2023;10:1091629. doi:10.3389/fcell.2022.1091629 Epub:
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Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Christodoulou N, Skourides PA. Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development. Front Cell Dev Biol. 2023;10:1091629. doi:10.3389/fcell.2022.1091629. |
Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs
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Citation:
Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2215071120. doi: 10.1073/pnas.2215071120. Epub 2023 Jan 9 Epub:
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CAG trinucleotide repeat expansions cause several neurodegenerative diseases, including Huntington's disease and... Delivery Method:
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cell culture: U-2OS cells (ATCC, HTB-96) Citation Extract: Das MR, Chang Y, Anderson R, Saunders RA, Zhang N, Tomberlin CP, Vale RD, Jain A. Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2215071120. doi: 10.1073/pnas.2215071120. Epub 2023 Jan 9. |
Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction
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Citation:
Development. 2023 Jan 1;150(1):dev201058. doi: 10.1242/dev.201058. Epub 2023 Jan 12 Epub:
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Many animals achieve sperm chromatin compaction and stabilisation by replacing canonical histones with sperm nuclear basic... Delivery Method:
microinjection Organism or Cell Type:
Hydractinia symbiolongicarpus (cnidarian) Citation Extract: Török A, Browne MJG, Vilar JC, Patwal I, DuBuc TQ, Febrimarsa, Atcheson E, Frank U, Gornik SG, Flaus A. Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction. Development. 2023 Jan 1;150(1):dev201058. doi: 10.1242/dev.201058. Epub 2023 Jan 12. |
C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity
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Citation:
Org Biomol Chem. 2023 Jan 12. doi: 10.1039/d2ob01759h. Online ahead of print Epub:
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C5-substituted uridine and cytidine morpholino chlorophosphoramidate monomers were synthesized and incorporated into a 12-mer... Citation Extract: Das A, Ghosh A, Sinha S. C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity. Org Biomol Chem. 2023 Jan 12. doi: 10.1039/d2ob01759h. Online ahead of print. |
Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs
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Citation:
Sci Rep. 2023 Jan 11;13(1):94. doi: 10.1038/s41598-022-26614-z Epub:
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Myotonic dystrophy type 1 (DM1) is caused by expanded CTG repeats (CTGexp) in the dystrophia myotonica protein kinase (DMPK)... Delivery Method:
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cell culture: patient-derived iPSCs differentiated to myotubes Citation Extract: Kawada R, Jonouchi T, Kagita A, Sato M, Hotta A, Sakurai H. Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs. Sci Rep. 2023 Jan 11;13(1):94. doi: 10.1038/s41598-022-26614-z. |
maea affects head formation through ß-catenin degradation during early Xenopus laevis development
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Citation:
Dev Growth Differ. 2022 Nov 28. doi: 10.1111/dgd.12828. Online ahead of print Epub:
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Canonical Wnt signalling plays important roles in early embryogenesis, such as axis formation due to its activation and head... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Goto T, Shibuya H. maea affects head formation through ß-catenin degradation during early Xenopus laevis development. Dev Growth Differ. 2022 Nov 28. doi: 10.1111/dgd.12828. Online ahead of print. |