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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA

Authors:
Chan SN, Pek JW
Citation:
EMBO Rep. 2022 Dec 19:e54350. doi: 10.15252/embr.202154350. Online ahead of print
Epub:
Not Epub
Abstract:
Stable intronic sequence RNAs (sisRNAs) are stable, long noncoding RNAs containing intronic sequences. While sisRNAs have been...
Link:
https://www.embopress.org/doi/abs/10.15252/embr.202154350
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: MDA-MB-231 and HEK293T
Citation Extract:
Chan SN, Pek JW. Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA. EMBO Rep. 2022 Dec 19:e54350. doi: 10.15252/embr.202154350. Online ahead of print.

SCGN deficiency is a risk factor for autism spectrum disorder

Authors:
Liu Z, Tan S, Zhou L, Chen L, Liu M, Wang W, Tang Y, Yang Q, Chi S, Jiang P, Zhang Y, Cui Y, Qin J, Hu X, Li S, Liu Q, Chen L, Li S, Burstein E, Li W, Zhang X, Mo X, Jia D
Citation:
Signal Transduct Target Ther. 2023 Jan 2;8(1):3. doi: 10.1038/s41392-022-01225-2
Epub:
Not Epub
Abstract:
Autism spectrum disorder (ASD) affects 1-2% of all children and poses a great social and economic challenge for the globe. As a...
Link:
https://www.nature.com/articles/s41392-022-01225-2
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Z, Tan S, Zhou L, Chen L, Liu M, Wang W, Tang Y, Yang Q, Chi S, Jiang P, Zhang Y, Cui Y, Qin J, Hu X, Li S, Liu Q, Chen L, Li S, Burstein E, Li W, Zhang X, Mo X, Jia D. SCGN deficiency is a risk factor for autism spectrum disorder. Signal Transduct Target Ther. 2023 Jan 2;8(1):3. doi: 10.1038/s41392-022-01225-2.

Morpholino Mediated Gene Editing: A Gene Knockdown Technique Using Translational Blocking Morpholino Oligonucleotides in Single-Celled Cavefish Eggs

Authors:
JoVE staff (?) - this information paywalled
Citation:
JoVE Encyclopedia of Experiments: Biological Techniques. JoVE, Cambridge, MA, (2022?)
Epub:
Not Epub
Abstract:
paywalled
Link:
https://www.jove.com/v/21011/morpholino-mediated-gene-editing-a-gene-knockdown-technique-using-translational-blocking-morpholino-oligonucleotides-in-single-celled-cavefish-eggs
Delivery Method:
microinjection
Organism or Cell Type:
cavefish
Citation Extract:
JoVE staff (?) - this information paywalled. Morpholino Mediated Gene Editing: A Gene Knockdown Technique Using Translational Blocking Morpholino Oligonucleotides in Single-Celled Cavefish Eggs. JoVE Encyclopedia of Experiments: Biological Techniques. JoVE, Cambridge, MA, (2022?).

Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells

Authors:
Leung AO, Yiu TC, Liu L, Tam HY, Gu S, Tu J, Pei D, Cheung HH
Citation:
Cell Biosci. 2022 Dec 31;12(1):212. doi: 10.1186/s13578-022-00939-8
Epub:
Not Epub
Abstract:
Background: Pathogenic mutations in WRN are a cause of premature aging disease Werner syndrome (WS). Besides accelerated aging...
Link:
https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-022-00939-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leung AO, Yiu TC, Liu L, Tam HY, Gu S, Tu J, Pei D, Cheung HH. Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells. Cell Biosci. 2022 Dec 31;12(1):212. doi: 10.1186/s13578-022-00939-8.

Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish

Authors:
Saralahti AK, Harjula S-KE, Rantapero T, Uusi-Mäkelä MIE, Kaasinen M, Junno M, Piippo H, Nykter M, Lohi O, Rounioja S, Parikka M, Rämet M
Citation:
PLoS Genet. 2023;19(1):e1010586. doi:10.1371/journal.pgen.1010586
Epub:
Not Epub
Abstract:
Streptococcus pneumoniae (pneumococcus) is one of the most frequent causes of pneumonia, sepsis and meningitis in humans, and...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010586
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Saralahti AK, Harjula S-KE, Rantapero T, Uusi-Mäkelä MIE, Kaasinen M, Junno M, Piippo H, Nykter M, Lohi O, Rounioja S, Parikka M, Rämet M. Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish. PLoS Genet. 2023;19(1):e1010586. doi:10.1371/journal.pgen.1010586.

α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish

Authors:
Hayashiji N, Kawahara G, Xu X, Fukuda T, Kerever A, Gu J, Hayashi YK, Arikawa-Hirasawa E
Citation:
Cells. 2022 Dec 29;12(1):144. doi: 10.3390/cells12010144
Epub:
Not Epub
Abstract:
Glycosylation is an important mechanism regulating various biological processes, including intercellular signaling and adhesion...
Link:
https://www.mdpi.com/2073-4409/12/1/144
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hayashiji N, Kawahara G, Xu X, Fukuda T, Kerever A, Gu J, Hayashi YK, Arikawa-Hirasawa E. α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish. Cells. 2022 Dec 29;12(1):144. doi: 10.3390/cells12010144.

The Male-Biased Expression of miR-2954 Is Involved in the Male Pathway of Chicken Sex Differentiation

Authors:
Cheng Y, Zhang Z, Zhang G, Chen L, Zeng C, Liu X, Feng Y
Citation:
Cells. 2022 Dec 20;12(1):4. doi: 10.3390/cells12010004
Epub:
Not Epub
Abstract:
Many expression data showed miRNAs have a potential function on regulating gonadal differentiation in animals, but their...
Link:
https://www.mdpi.com/2073-4409/12/1/4
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Cheng Y, Zhang Z, Zhang G, Chen L, Zeng C, Liu X, Feng Y. The Male-Biased Expression of miR-2954 Is Involved in the Male Pathway of Chicken Sex Differentiation. Cells. 2022 Dec 20;12(1):4. doi: 10.3390/cells12010004.

Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier

Authors:
Jonusaite S, Oulhen N, Izumi Y, Furuse M, Yamamoto T, Sakamoto N, Wessel G, Heyland A
Citation:
Dev Biol. 2022 Dec 29;495:21-34. doi: 10.1016/j.ydbio.2022.12.007. Online ahead of print
Epub:
Not Epub
Abstract:
Septate junctions (SJs) evolved as cell-cell junctions that regulate the paracellular barrier and integrity of epithelia in...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160622002366
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Jonusaite S, Oulhen N, Izumi Y, Furuse M, Yamamoto T, Sakamoto N, Wessel G, Heyland A. Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier. Dev Biol. 2022 Dec 29;495:21-34. doi: 10.1016/j.ydbio.2022.12.007. Online ahead of print.

Ste20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes

Authors:
Song K, Jiang X, Xu X, Chen Y, Zhang J, Tian Y, Wang Q, Weng J, Liang Y, Ma W
Citation:
Cell Prolif. 2022 Dec 29:e13391. doi: 10.1111/cpr.13391. Online ahead of print
Epub:
Not Epub
Abstract:
Ste20-like kinase (SLK) is involved in cell proliferation and migration in somatic cells. This study aims to explore SLK...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/cpr.13391
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Song K, Jiang X, Xu X, Chen Y, Zhang J, Tian Y, Wang Q, Weng J, Liang Y, Ma W. Ste20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes. Cell Prolif. 2022 Dec 29:e13391. doi: 10.1111/cpr.13391. Online ahead of print.

Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development

Authors:
Li W, Wen L, Rathod B, Gingras AC, Ley K, Lee HS
Citation:
Life Sci Alliance. 2022 Dec 27;6(3):e202201800. doi: 10.26508/lsa.202201800. Print 2023 Mar
Epub:
Not Epub
Abstract:
Direct contact between cells expressing either ephrin ligands or Eph receptor tyrosine kinase produces diverse developmental...
Link:
https://www.life-science-alliance.org/content/6/3/e202201800
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li W, Wen L, Rathod B, Gingras AC, Ley K, Lee HS. Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development. Life Sci Alliance. 2022 Dec 27;6(3):e202201800. doi: 10.26508/lsa.202201800. Print 2023 Mar.

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