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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny

Authors:
Romanos M, Allio G, Roussigné M, Combres L, Escalas N, Soula C, Médevielle F, Steventon B, Trescases A, Bénazéraf B
Citation:
eLife. 2021;10:e66588 doi:10.7554/eLife.66588
Epub:
Not Epub
Abstract:
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know...
Delivery Method:
electroporation
Organism or Cell Type:
Coturnix japonica (quail)
Citation Extract:
Romanos M, Allio G, Roussigné M, Combres L, Escalas N, Soula C, Médevielle F, Steventon B, Trescases A, Bénazéraf B. Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny. eLife. 2021;10:e66588 doi:10.7554/eLife.66588.

SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling

Authors:
Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani NF, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp H-J, Lappalainen P, Ivaska J
Citation:
Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.09.022
Epub:
Not Epub
Abstract:
Actin-rich cellular protrusions direct versatile biological processes from cancer cell invasion to dendritic spine development...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani NF, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp H-J, Lappalainen P, Ivaska J. SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling. Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.09.022.

The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration

Authors:
Ivanova AS, Tereshina MB, Araslanova KR, Martynova NY, Zaraisky AG
Citation:
Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940
Epub:
Not Epub
Abstract:
Warm-blooded vertebrates regenerate lost limbs and their parts in general much worse than fishes and amphibians. We previously...
Delivery Method:
microinjection, Vivo-Morpholino
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ivanova AS, Tereshina MB, Araslanova KR, Martynova NY, Zaraisky AG. The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration. Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940.

The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway

Authors:
Zhao Y, Wu M, Li J, Meng P, Chen J, Huang, Xu J, Wen Z, Zhang W, Zhang Y
Citation:
Cell Death Dis. 2021;12(10):906. doi:10.1038/s41419-021-04215-4
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Y, Wu M, Li J, Meng P, Chen J, Huang, Xu J, Wen Z, Zhang W, Zhang Y. The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway. Cell Death Dis. 2021;12(10):906. doi:10.1038/s41419-021-04215-4.

Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues

Authors:
Cerveny KL, Bronstein H, Hagen O, Lamb DB, Martin G, Tower I, Van Duzer A, Welch E, Varga M
Citation:
microPublication Biology. 2021.10.17912/micropub.biology.000481. doi:10.17912/micropub.biology.000481
Epub:
Not Epub
Abstract:
Cell behaviors such as survival, proliferation, and death are governed by a multitude of cues, both intrinsic and extrinsic. To...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cerveny KL, Bronstein H, Hagen O, Lamb DB, Martin G, Tower I, Van Duzer A, Welch E, Varga M. Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues. microPublication Biology. 2021.10.17912/micropub.biology.000481. doi:10.17912/micropub.biology.000481.

Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker

Authors:
Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL
Citation:
BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z
Epub:
Not Epub
Abstract:
Background: Sinoatrial Node (SAN) is part of the cardiac conduction system, which controls the rhythmic contraction of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL. Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker. BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z.

Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus

Authors:
Johansen MD, Alcaraz M, Dedrick RM, Roquet-Banères F, Hamela C, Hatfull GF, Kremer L
Citation:
Dis Model Mech. 2021 Sep 1;14(9):dmm049159. doi: 10.1242/dmm.049159. Epub 2021 Sep 16
Epub:
Not Epub
Abstract:
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF) patients, leaving...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Johansen MD, Alcaraz M, Dedrick RM, Roquet-Banères F, Hamela C, Hatfull GF, Kremer L. Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus. Dis Model Mech. 2021 Sep 1;14(9):dmm049159. doi: 10.1242/dmm.049159. Epub 2021 Sep 16.

Glypican 4 mediates Wnt transport between germ layers via signaling filopodia

Authors:
Hu B Rodriguez JJ Balaraju AK, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F
Citation:
J Cell Biol. 2021;220(12):e202009082. doi:10.1083/jcb.202009082
Epub:
Not Epub
Abstract:
Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu B Rodriguez JJ Balaraju AK, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F. Glypican 4 mediates Wnt transport between germ layers via signaling filopodia. J Cell Biol. 2021;220(12):e202009082. doi:10.1083/jcb.202009082.

The Embryonic Key Pluripotent Factor NANOG Mediates Glioblastoma Cell Migration via the SDF1/CXCR4 Pathway

Authors:
Sánchez-Sánchez AV, García-España A, Sánchez-Gómez P, Font-de-Mora J, Merino M, Mullor JL
Citation:
Int J Mol Sci. 2021;22(19):10620. doi:10.3390/ijms221910620
Epub:
Not Epub
Abstract:
NANOG is a key transcription factor required for maintaining pluripotency of embryonic stem cells. Elevated NANOG expression...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Sánchez-Sánchez AV, García-España A, Sánchez-Gómez P, Font-de-Mora J, Merino M, Mullor JL. The Embryonic Key Pluripotent Factor NANOG Mediates Glioblastoma Cell Migration via the SDF1/CXCR4 Pathway. Int J Mol Sci. 2021;22(19):10620. doi:10.3390/ijms221910620 .

Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera

Authors:
Poganik JR, Huang K-T, Parvez S, Zhao Y, Raja S, Long MJC, Aye Y
Citation:
Nat Comm. 2021;12(1):5736. doi:10.1038/s41467-021-25466-x
Epub:
Not Epub
Abstract:
Despite the emerging importance of reactive electrophilic drugs, deconvolution of their principal targets remains difficult....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poganik JR, Huang K-T, Parvez S, Zhao Y, Raja S, Long MJC, Aye Y. Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera. Nat Comm. 2021;12(1):5736. doi:10.1038/s41467-021-25466-x.

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