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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Meis1, Hi1α, and GATA1 are integrated into a hierarchical regulatory network to mediate primitive erythropoiesis

Authors:
Chung HY, Lin BA, Lin YX, Chang CW, Tzou WS, Pei TW, Hu CH
Citation:
FASEB J. 2021 Oct;35(10):e21915. doi: 10.1096/fj.202001044RRR
Epub:
Not Epub
Abstract:
During development, erythroid cells are generated by two waves of hematopoiesis. In zebrafish, primitive erythropoiesis takes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chung HY, Lin BA, Lin YX, Chang CW, Tzou WS, Pei TW, Hu CH. Meis1, Hi1α, and GATA1 are integrated into a hierarchical regulatory network to mediate primitive erythropoiesis. FASEB J. 2021 Oct;35(10):e21915. doi: 10.1096/fj.202001044RRR.

Estrogen-related receptor γ2 controls NaCl uptake to maintain ionic homeostasis

Authors:
Shih SW, Yan JJ, Wang YH, Tsou YL, Chiu L, Tseng YC, Chou MY, Hwang PP
Citation:
J Endocrinol. 2021 Sep 1:JOE-21-0112.R2. doi: 10.1530/JOE-21-0112. Online ahead of print. PMID: 34494970
Epub:
Yes
Abstract:
Estrogen-related receptors (ERRs) are known to function in mammalian kidney as key regulators of ion transport-related genes;...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Shih SW, Yan JJ, Wang YH, Tsou YL, Chiu L, Tseng YC, Chou MY, Hwang PP. Estrogen-related receptor γ2 controls NaCl uptake to maintain ionic homeostasis. J Endocrinol. 2021 Sep 1:JOE-21-0112.R2. doi: 10.1530/JOE-21-0112. Online ahead of print. PMID: 34494970.

Numb is required for optimal contraction of skeletal muscle

Authors:
De Gasperi R, Mo C, Azulai D, Wang Z, Harlow LM, Du Y, Graham Z, Pan J, Liu X-H, Guo L, Zhang B, Ko F, Raczkowski AM, Bauman WA, Goulbourne CN, Zhao W, Brotto M, Cardozo CP
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.03.453960
Epub:
Not Epub
Abstract:
Background: The role of Numb, a protein that is important for cell fate and development was investigated in adult skeletal...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: mouse primary myotubes
Citation Extract:
De Gasperi R, Mo C, Azulai D, Wang Z, Harlow LM, Du Y, Graham Z, Pan J, Liu X-H, Guo L, Zhang B, Ko F, Raczkowski AM, Bauman WA, Goulbourne CN, Zhao W, Brotto M, Cardozo CP. Numb is required for optimal contraction of skeletal muscle. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.03.453960.

Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l

Authors:
Kim H-S, Green YS, Xie Y, Christian JL
Citation:
Proc Nat Acad Sci USA. 2021:118(36)e2104661118. doi:10.1073/pnas.2104661118
Epub:
Yes
Abstract:
Toll-like receptor 4 (Tlr) interactor with leucine-rich repeats (Tril) functions as a Tlr coreceptor to mediate innate immunity...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim H-S, Green YS, Xie Y, Christian JL. Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l. Proc Nat Acad Sci USA. 2021:118(36)e2104661118. doi:10.1073/pnas.2104661118.

Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase

Authors:
Li B, Chen K, Liu F, Zhang J, Chen X, Chen T, Chen Q, Yao Y, Hu W, Wang L, Wu Y
Citation:
Front Cardiovasc Med. 2021;8:1000. doi:10.3389/fcvm.2021.724846
Epub:
Not Epub
Abstract:
Background: Mitochondrial aminoacyl-tRNA synthetases (mtARSs) catalyze the binding of specific amino acids to their cognate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li B, Chen K, Liu F, Zhang J, Chen X, Chen T, Chen Q, Yao Y, Hu W, Wang L, Wu Y. Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase. Front Cardiovasc Med. 2021;8:1000. doi:10.3389/fcvm.2021.724846.

Efficient Generation of Knock-In Zebrafish Models for Inherited Disorders Using CRISPR-Cas9 Ribonucleoprotein Complexes

Authors:
de Vrieze E, de Bruijn SE, Reurink J, Broekman S, van de Riet V, Aben M, Kremer H, van Wijk E
Citation:
Int J Mol Sci. 2021; 22(17):9429. doi:10.3390/ijms22179429
Epub:
Not Epub
Abstract:
CRISPR-Cas9-based genome-editing is a highly efficient and cost-effective method to generate zebrafish loss-of-function alleles...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Vrieze E, de Bruijn SE, Reurink J, Broekman S, van de Riet V, Aben M, Kremer H, van Wijk E. Efficient Generation of Knock-In Zebrafish Models for Inherited Disorders Using CRISPR-Cas9 Ribonucleoprotein Complexes. Int J Mol Sci. 2021; 22(17):9429. doi:10.3390/ijms22179429.

The CCAAT/Enhancer Binding Protein Beta (cebpb) is essential for the development of enveloping layer (EVL) in zebrafish

Authors:
Zhang X, Wu Z, Bu M, Hu R, Zhang X, Li W, Chen L
Citation:
Aquac Fish. 2021;[Epub] doi:10.1016/j.aaf.2021.07.003
Epub:
Yes
Abstract:
Epiboly, the coordinated spreading of the enveloping layer (EVL), the yolk syncytial layer (YSL) and the deep cells (DCs)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang X, Wu Z, Bu M, Hu R, Zhang X, Li W, Chen L. The CCAAT/Enhancer Binding Protein Beta (cebpb) is essential for the development of enveloping layer (EVL) in zebrafish. Aquac Fish. 2021;[Epub] doi:10.1016/j.aaf.2021.07.003.

Ptk7 Is Dynamically Localized at Neural Crest Cell-Cell Contact Sites and Functions in Contact Inhibition of Locomotion

Authors:
Grund A, Till K, Giehl K, Borchers A
Citation:
Int J Mol Sci. 2021;22(17):9324. doi:10.3390/ijms22179324
Epub:
Not Epub
Abstract:
Neural crest (NC) cells are highly migratory cells that contribute to various vertebrate tissues, and whose migratory behaviors...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Grund A, Till K, Giehl K, Borchers A. Ptk7 Is Dynamically Localized at Neural Crest Cell-Cell Contact Sites and Functions in Contact Inhibition of Locomotion. Int J Mol Sci. 2021;22(17):9324. doi:10.3390/ijms22179324.

Loss of Ift74 Leads to Slow Photoreceptor Degeneration and Ciliogenesis Defects in Zebrafish

Authors:
Zhu P, Xu J, Wang Y, Zhao C
Citation:
Int J Mol Sci. 2021;22(17):9329. doi:10.3390/ijms22179329
Epub:
Not Epub
Abstract:
Cilia are microtubule-based structures projecting from the cell surface that perform diverse biological functions. Ciliary...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu P, Xu J, Wang Y, Zhao C. Loss of Ift74 Leads to Slow Photoreceptor Degeneration and Ciliogenesis Defects in Zebrafish. Int J Mol Sci. 2021;22(17):9329. doi:10.3390/ijms22179329.

NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis

Authors:
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Citation:
Cell Res. 2021 Sep 3. doi: 10.1038/s41422-021-00560-3. Online ahead of print
Epub:
Yes
Abstract:
Primary cilia extending from mother centrioles are essential for vertebrate development and homeostasis maintenance. Centriolar...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S. NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis. Cell Res. 2021 Sep 3. doi: 10.1038/s41422-021-00560-3. Online ahead of print.

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