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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Neural crest specification and migration independently require NSD3-related lysine methyltransferase activity
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Citation:
Mol Biol Cell. 2014 Dec 15;25(25):4174-86. doi: 10.1091/mbc.E13-12-0744. Epub 2014 Oct 15 Epub:
Not Epub Abstract:
Neural crest precursors express genes that cause them to become migratory, multipotent cells, distinguishing them from adjacent... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Jacques-Fricke BT, Gammill LS. Neural crest specification and migration independently require NSD3-related lysine methyltransferase activity. Mol Biol Cell. 2014 Dec 15;25(25):4174-86. doi: 10.1091/mbc.E13-12-0744. Epub 2014 Oct 15. |
GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration
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Citation:
Mol Biol Cell. 2014 Dec 15;25(25):4072-82. doi: 10.1091/mbc.E14-05-0970. Epub 2014 Oct 8 Epub:
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ADAMs are cell surface metalloproteases that control multiple biological processes by cleaving signaling and adhesion molecules... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Abbruzzese G, Cousin H, Salicioni AM, Alfandari D. GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration. Mol Biol Cell. 2014 Dec 15;25(25):4072-82. doi: 10.1091/mbc.E14-05-0970. Epub 2014 Oct 8. |
PICALM modulates autophagy activity and tau accumulation
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Citation:
Nat Commun. 2014 Sep 22;5:4998. doi: 10.1038/ncomms5998 Epub:
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Genome-wide association studies have identified several loci associated with Alzheimer’s disease (AD), including proteins... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Moreau K, Fleming A, Imarisio S, Lopez Ramirez A, Mercer JL, Jimenez-Sanchez M, Bento CF, Puri C, Zavodszky E, Siddiqi F, Lavau CP, Betton M, O'Kane CJ, Wechsler DS, Rubinsztein DC. PICALM modulates autophagy activity and tau accumulation. Nat Commun. 2014 Sep 22;5:4998. doi: 10.1038/ncomms5998. |
Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development
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Citation:
FASEB J. 2014 Mar;28(3):1248-67. doi: 10.1096/fj.13-239178. Epub 2013 Dec 5 Epub:
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The bone morphogenetic protein (BMP) signaling pathways have important roles in embryonic development and cellular homeostasis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holtzhausen A, Golzio C, How T, Lee YH, Schiemann WP, Katsanis N, Blobe GC. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014 Mar;28(3):1248-67. doi: 10.1096/fj.13-239178. Epub 2013 Dec 5. |
Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish
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Citation:
Basic Res Cardiol. 2015 Mar;110(2):14. doi: 10.1007/s00395-015-0468-7. Epub 2015 Feb 20 Epub:
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The genetic underpinnings of heart rate regulation are only poorly understood. In search for genetic regulators of cardiac... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Keßler M, Berger IM, Just S, Rottbauer W. Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish. Basic Res Cardiol. 2015 Mar;110(2):14. doi: 10.1007/s00395-015-0468-7. Epub 2015 Feb 20. |
Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth
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Citation:
Dev Cell. 2014 Feb 24;28(4):423-37. doi: 10.1016/j.devcel.2014.01.006. Epub 2014 Feb 13 Epub:
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The liver and pancreas arise from common endodermal progenitors. How these distinct cell fates are specified is poorly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell. 2014 Feb 24;28(4):423-37. doi: 10.1016/j.devcel.2014.01.006. Epub 2014 Feb 13. |
A Missense Change in the ATG4D Gene Links Aberrant Autophagy to a Neurodegenerative Vacuolar Storage Disease
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Citation:
PLoS Genet. 2015 Apr 15;11(4):e1005169. doi: 10.1371/journal.pgen.1005169. eCollection 2015 Apr Epub:
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Inherited neurodegenerative disorders are debilitating diseases that occur across different species. We have performed clinical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kyöstilä K, Syrjä P, Jagannathan V, Chandrasekar G, Jokinen TS, Seppälä EH, Becker D, Drögemüller M, Dietschi E, Drögemüller C, Lang J, Steffen F, Rohdin C, Jäderlund KH, Lappalainen AK, Hahn K, Wohlsein P, Baumgärtner W, Henke D, Oevermann A, Kere J, Lohi H, Leeb T. A Missense Change in the ATG4D Gene Links Aberrant Autophagy to a Neurodegenerative Vacuolar Storage Disease. PLoS Genet. 2015 Apr 15;11(4):e1005169. doi: 10.1371/journal.pgen.1005169. eCollection 2015 Apr. |
Quantitative Analysis of PMLA Nanoconjugate Components after Backbone Cleavage
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Citation:
Int J Mol Sci. 2015;16(4):8607-20. doi:10.3390/ijms16048607 Epub:
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Multifunctional polymer nanoconjugates containing multiple components show great promise in cancer therapy, but in most cases... Delivery Method:
nanoparticle Citation Extract: Ding H, Patil R, Portilla-Arias J, Black KL, Ljubimova JY, Eggehard Holler E. Quantitative Analysis of PMLA Nanoconjugate Components after Backbone Cleavage. Int J Mol Sci. 2015;16(4):8607-20. doi:10.3390/ijms16048607. |
Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo
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Citation:
Elife. 2015 Apr 15;4. doi: 10.7554/eLife.05279 Epub:
Not Epub Abstract:
Cell migration and polarization is controlled by signals in the environment. Migrating cells typically form filopodia that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meyen D, Tarbashevich K, Banisch TU, Wittwer C, Reichman-Fried M, Maugis B, Grimaldi C, Messerschmidt EM, Raz E. Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivo. Elife. 2015 Apr 15;4. doi: 10.7554/eLife.05279. |
Oral-aboral axis specification in the sea urchin embryo, IV: hypoxia radializes embryos by preventing the initial spatialization of nodal activity
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Citation:
Dev Biol. 2014 Feb 15;386(2):302-7. doi: 10.1016/j.ydbio.2013.12.035. Epub 2013 Dec 31 Epub:
Not Epub Abstract:
The oral-aboral axis of the sea urchin embryo is specified conditionally via a regulated feedback circuit involving the... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Coffman JA, Wessels A, DeSchiffart C, Rydlizky K. Oral-aboral axis specification in the sea urchin embryo, IV: hypoxia radializes embryos by preventing the initial spatialization of nodal activity. Dev Biol. 2014 Feb 15;386(2):302-7. doi: 10.1016/j.ydbio.2013.12.035. Epub 2013 Dec 31. |