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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Depletion of melanoma fn14 by oligonucleotide-mediated exon skipping

Authors:
KM Beck, S Ramaswami, W Zeng and MS Hayden
Citation:
J Invest Dermatol. 2015;135:S106–S113. doi:10.1038/jid.2015.77
Epub:
Not Epub
Abstract:
Fibroblast growth factor inducible 14 (Fn14) is the receptor for the TNF family cytokine TNF-like weak inducer of apoptosis (...
Organism or Cell Type:
cell culture: human melanoma cell lines
Citation Extract:
KM Beck, S Ramaswami, W Zeng and MS Hayden. Depletion of melanoma fn14 by oligonucleotide-mediated exon skipping. J Invest Dermatol. 2015;135:S106–S113. doi:10.1038/jid.2015.77.

Characterization of Tetratricopeptide Repeat-Containing Proteins Critical for Cilia Formation and Function

Authors:
Xu Y, Cao J, Huang S, Feng D, Zhang W, Zhu X, Yan X
Citation:
PLoS One. 2015 Apr 10;10(4):e0124378. doi: 10.1371/journal.pone.0124378. eCollection 2015
Epub:
Not Epub
Abstract:
Cilia formation and function require a special set of trafficking machinery termed intraflagellar transport (IFT), consisting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu Y, Cao J, Huang S, Feng D, Zhang W, Zhu X, Yan X. Characterization of Tetratricopeptide Repeat-Containing Proteins Critical for Cilia Formation and Function. PLoS One. 2015 Apr 10;10(4):e0124378. doi: 10.1371/journal.pone.0124378. eCollection 2015.

The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output

Authors:
Yvette Stijf-Bultsma Y, Sommer L, Tauber M, Baalbaki M, Giardoglou P, Jones DR, Gelato KA, van Pelt J, Shah Z, Rahnamoun H, Toma C, Anderson KE, Hawkins P, Lauberth SM, Haramis A-PG, Hart D, Fischle W, Divecha N
Citation:
Molec Cell. 2015;[Epub ahead of print] doi:10.1016/j.molcel.2015.03.009
Epub:
Yes
Abstract:
Phosphoinositides (PI) are important signaling molecules in the nucleus that influence gene expression. However, if and how...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yvette Stijf-Bultsma Y, Sommer L, Tauber M, Baalbaki M, Giardoglou P, Jones DR, Gelato KA, van Pelt J, Shah Z, Rahnamoun H, Toma C, Anderson KE, Hawkins P, Lauberth SM, Haramis A-PG, Hart D, Fischle W, Divecha N. The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output. Molec Cell. 2015;[Epub ahead of print] doi:10.1016/j.molcel.2015.03.009.

Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination

Authors:
Nakayama T, Al-Maawali A, El-Quessny M, Rajab A, Khalil S, Stoler JM, Tan W-H, Nasir R, Schmitz-Abe K, Hill RS, Partlow JN, Al-Saffar M, Servattalab S, LaCoursiere CM, Tambunan DE, Coulter ME, Elhosary PC, Gorski G, Barkovich AJ, Markianos K, Poduri A, Mochida GH
Citation:
Am J Hum G. 2015;[Epub ahead of print] doi:10.1016/j.ajhg.2015.03.003
Epub:
Yes
Abstract:
Despite recent advances in understanding the genetic bases of microcephaly, a large number of cases of microcephaly remain...
Organism or Cell Type:
zebrafish
Citation Extract:
Nakayama T, Al-Maawali A, El-Quessny M, Rajab A, Khalil S, Stoler JM, Tan W-H, Nasir R, Schmitz-Abe K, Hill RS, Partlow JN, Al-Saffar M, Servattalab S, LaCoursiere CM, Tambunan DE, Coulter ME, Elhosary PC, Gorski G, Barkovich AJ, Markianos K, Poduri A, Mochida GH. Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum G. 2015;[Epub ahead of print] doi:10.1016/j.ajhg.2015.03.003.

Deiodinase Knockdown during Early Zebrafish Development Affects Growth, Development, Energy Metabolism, Motility and Phototransduction

Authors:
Bagci E, Heijlen M, Vergauwen L, Hagenaars A, Houbrechts AM, Esguerra CV, Blust R, Darras VM, Knapen D
Citation:
PLoS One. 2015 Apr 9;10(4):e0123285. doi: 10.1371/journal.pone.0123285. eCollection 2015
Epub:
Not Epub
Abstract:
Thyroid hormone (TH) balance is essential for vertebrate development. Deiodinase type 1 (D1) and type 2 (D2) increase and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bagci E, Heijlen M, Vergauwen L, Hagenaars A, Houbrechts AM, Esguerra CV, Blust R, Darras VM, Knapen D. Deiodinase Knockdown during Early Zebrafish Development Affects Growth, Development, Energy Metabolism, Motility and Phototransduction. PLoS One. 2015 Apr 9;10(4):e0123285. doi: 10.1371/journal.pone.0123285. eCollection 2015.

The Proprotein Convertase Subtilisin/Kexin FurinA Regulates Zebrafish Host Response against Mycobacterium marinum

Authors:
Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M
Citation:
Infect Immun. April 2015 83:4 1431-1442; Accepted manuscript posted online 26 January 2015, doi: 10.1128/IAI.03135-14
Epub:
Not Epub
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M. The Proprotein Convertase Subtilisin/Kexin FurinA Regulates Zebrafish Host Response against Mycobacterium marinum. Infect Immun. April 2015 83:4 1431-1442; Accepted manuscript posted online 26 January 2015, doi: 10.1128/IAI.03135-14.

Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

Authors:
Chu B-B, Liao Y-C, Qi W, Xie C, Du X, Wang J, Yang H, Miao H-H, Li B-L, Song B-L
Citation:
Cell. 2015;291-306. doi:10.1016/j.cell.2015.02.019
Epub:
Not Epub
Abstract:
Cholesterol is dynamically transported among organelles, which is essential for multiple cellular functions. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chu B-B, Liao Y-C, Qi W, Xie C, Du X, Wang J, Yang H, Miao H-H, Li B-L, Song B-L. Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts. Cell. 2015;291-306. doi:10.1016/j.cell.2015.02.019.

Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells

Authors:
Boer EF, Howell ED, Schilling TF, Jette CA, Stewart RA
Citation:
PLoS Genet. 2015 Jan 21;11(1):e1004946. doi: 10.1371/journal.pgen.1004946. eCollection 2015 Jan
Epub:
Not Epub
Abstract:
Directional migration of neural crest (NC) cells is essential for patterning the vertebrate embryo, including the craniofacial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boer EF, Howell ED, Schilling TF, Jette CA, Stewart RA. Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells. PLoS Genet. 2015 Jan 21;11(1):e1004946. doi: 10.1371/journal.pgen.1004946. eCollection 2015 Jan.

HOMER2, a Stereociliary Scaffolding Protein, Is Essential for Normal Hearing in Humans and Mice

Authors:
Azaiez H, Decker AR, Booth KT, Simpson AC, Shearer AE, Huygen PL, Bu F, Hildebrand MS, Ranum PT, Shibata SB, Turner A, Zhang Y, Kimberling WJ, Cornell RA, Smith RJ
Citation:
PLoS Genet. 2015 Mar 27;11(3):e1005137. doi: 10.1371/journal.pgen.1005137. eCollection 2015 Feb
Epub:
Not Epub
Abstract:
Hereditary hearing loss is a clinically and genetically heterogeneous disorder. More than 80 genes have been implicated to date...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Azaiez H, Decker AR, Booth KT, Simpson AC, Shearer AE, Huygen PL, Bu F, Hildebrand MS, Ranum PT, Shibata SB, Turner A, Zhang Y, Kimberling WJ, Cornell RA, Smith RJ. HOMER2, a Stereociliary Scaffolding Protein, Is Essential for Normal Hearing in Humans and Mice. PLoS Genet. 2015 Mar 27;11(3):e1005137. doi: 10.1371/journal.pgen.1005137. eCollection 2015 Feb.

The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule

Authors:
Oltrabella F, Pietka G, Ramirez IB-R, Mironov A, Starborg T, Drummond IA, Hinchliffe KA, Lowe M
Citation:
PLoS Genet. 2015;11(4):e1005058. doi:10.1371/journal.pgen.1005058
Epub:
Not Epub
Abstract:
Lowe syndrome and Dent-2 disease are caused by mutation of the inositol 5-phosphatase OCRL1. Despite our increased...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oltrabella F, Pietka G, Ramirez IB-R, Mironov A, Starborg T, Drummond IA, Hinchliffe KA, Lowe M. The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule. PLoS Genet. 2015;11(4):e1005058. doi:10.1371/journal.pgen.1005058.

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