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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisions

Authors:
Žigman M, Trinh le A, Fraser SE, Moens CB
Citation:
Curr Biol. 2011 Jan 11;21(1):79-86. doi: 10.1016/j.cub.2010.12.005. Epub 2010 Dec 23
Epub:
Not Epub
Abstract:
How control of subcellular events in single cells determines morphogenesis on the scale of the tissue is largely unresolved....
Link:
http://www.sciencedirect.com/science/article/pii/S0960982210015915
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Žigman M, Trinh le A, Fraser SE, Moens CB. Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisions. Curr Biol. 2011 Jan 11;21(1):79-86. doi: 10.1016/j.cub.2010.12.005. Epub 2010 Dec 23.

TALE factors poise promoters for activation by Hox proteins

Authors:
Choe SK, Ladam F, Sagerström CG
Citation:
Dev Cell. 2014 Jan 27;28(2):203-11. doi: 10.1016/j.devcel.2013.12.011
Epub:
Not Epub
Abstract:
Hox proteins form complexes with TALE cofactors from the Pbx and Prep/Meis families to control transcription, but it remains...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807%2813%2900758-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choe SK, Ladam F, Sagerström CG. TALE factors poise promoters for activation by Hox proteins. Dev Cell. 2014 Jan 27;28(2):203-11. doi: 10.1016/j.devcel.2013.12.011.

TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types

Authors:
Nwagbara BU, Faris AE, Bearce EA, Erdogan B, Ebbert PT, Evans MF, Rutherford EL, Enzenbacher TB, Lowery LA
Citation:
Mol Biol Cell. 2014 Nov 1;25(21):3350-62. doi: 10.1091/mbc.E14-06-1121. Epub 2014 Sep 3
Epub:
Not Epub
Abstract:
Microtubule plus end dynamics are regulated by a conserved family of proteins called plus end-tracking proteins (+TIPs). It is...
Link:
http://www.molbiolcell.org/content/25/21/3350.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nwagbara BU, Faris AE, Bearce EA, Erdogan B, Ebbert PT, Evans MF, Rutherford EL, Enzenbacher TB, Lowery LA. TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types. Mol Biol Cell. 2014 Nov 1;25(21):3350-62. doi: 10.1091/mbc.E14-06-1121. Epub 2014 Sep 3.

Method for quantitative analysis of nonsense-mediated mRNA decay at the single cell level

Authors:
Pereverzev AP, Gurskaya NG, Ermakova GV, Kudryavtseva EI, Markina NM, Kotlobay AA, Lukyanov SA, Zaraisky AG, Lukyanov KA
Citation:
Sci Rep. 2015 Jan 12;5:7729. doi: 10.1038/srep07729
Epub:
Not Epub
Abstract:
Nonsense-mediated mRNA decay (NMD) is a ubiquitous mechanism of degradation of transcripts with a premature termination codon....
Link:
http://www.nature.com/srep/2015/150112/srep07729/full/srep07729.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pereverzev AP, Gurskaya NG, Ermakova GV, Kudryavtseva EI, Markina NM, Kotlobay AA, Lukyanov SA, Zaraisky AG, Lukyanov KA. Method for quantitative analysis of nonsense-mediated mRNA decay at the single cell level. Sci Rep. 2015 Jan 12;5:7729. doi: 10.1038/srep07729.

Notch3 establishes brain vascular integrity by regulating pericyte number

Authors:
Wang Y, Pan L, Moens CB, Appel B
Citation:
Development. 2014 Jan;141(2):307-17. doi: 10.1242/dev.096107. Epub 2013 Dec 4
Epub:
Not Epub
Abstract:
Brain pericytes are important regulators of brain vascular integrity, permeability and blood flow. Deficiencies of brain...
Link:
http://dev.biologists.org/content/141/2/307.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Pan L, Moens CB, Appel B. Notch3 establishes brain vascular integrity by regulating pericyte number. Development. 2014 Jan;141(2):307-17. doi: 10.1242/dev.096107. Epub 2013 Dec 4.

Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome

Authors:
Ben-Omran T, Fahiminiya S, Sorfazlian N, Almuriekhi M, Nawaz Z, Nadaf J, Khadija KA, Zaineddin S, Kamel H, Majewski J, Tropepe V
Citation:
J Med Genet. 2015;[Epub ahead of print] doi:10.1136/jmedgenet-2014-102707
Epub:
Yes
Abstract:
Background: Neuroanatomical defects are often present in children with severe developmental delay and intellectual disabilities...
Link:
http://jmg.bmj.com/content/early/2015/04/14/jmedgenet-2014-102707.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ben-Omran T, Fahiminiya S, Sorfazlian N, Almuriekhi M, Nawaz Z, Nadaf J, Khadija KA, Zaineddin S, Kamel H, Majewski J, Tropepe V. Nonsense mutation in the WDR73 gene is associated with Galloway-Mowat syndrome. J Med Genet. 2015;[Epub ahead of print] doi:10.1136/jmedgenet-2014-102707.

Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression

Authors:
Wong L, Power N, Miles A, Tropepe V
Citation:
Dev Biol. 2015 Apr 11. pii: S0012-1606(15)00171-2. doi: 10.1016/j.ydbio.2015.03.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Understanding the mechanisms that regulate the transition between the proliferative and a post-mitotic state of retinal...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615001712
Organism or Cell Type:
zebrafish
Citation Extract:
Wong L, Power N, Miles A, Tropepe V. Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression. Dev Biol. 2015 Apr 11. pii: S0012-1606(15)00171-2. doi: 10.1016/j.ydbio.2015.03.020. [Epub ahead of print].

An essential role for parathyroid hormone in gill formation and differentiation of ion-transporting cells in developing zebrafish

Authors:
Kwong RW, Perry SF
Citation:
Endocrinology. 2015 Apr 14:en20141968. [Epub ahead of print]
Epub:
Yes
Abstract:
In vertebrates, parathyroid hormone (PTH) is important for skeletogenesis and Ca2+ homeostasis. However, little is known about...
Link:
http://press.endocrine.org/doi/abs/10.1210/en.2014-1968
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kwong RW, Perry SF. An essential role for parathyroid hormone in gill formation and differentiation of ion-transporting cells in developing zebrafish. Endocrinology. 2015 Apr 14:en20141968. [Epub ahead of print].

Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model

Authors:
Martins Metelo A, Noonan HR, Xiang L, Jin Y, Baker R, Kamentsky L, Zhang Y, van Rooijen E, Shin J, Carpenter AE, Yeh JR, Peterson RT, Iliopoulos O
Citation:
J Clin Invest. 2015 Apr 13. pii: 73665. doi: 10.1172/JCI73665. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Patients with a germline mutation in von Hippel-Lindau (VHL) develop renal cell cancers and hypervascular tumors of the brain,...
Link:
http://www.jci.org/articles/view/73665
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Martins Metelo A, Noonan HR, Xiang L, Jin Y, Baker R, Kamentsky L, Zhang Y, van Rooijen E, Shin J, Carpenter AE, Yeh JR, Peterson RT, Iliopoulos O. Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model. J Clin Invest. 2015 Apr 13. pii: 73665. doi: 10.1172/JCI73665. [Epub ahead of print].

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

Authors:
Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI
Citation:
J Exp Med. 2015;[Epub ahead of print] doi:10.1084/jem.20141528
Epub:
Yes
Abstract:
Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The...
Link:
http://jem.rupress.org/content/early/2015/04/07/jem.20141528.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI. Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. J Exp Med. 2015;[Epub ahead of print] doi:10.1084/jem.20141528 .

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