You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Functional Characterization of the spf/ash Splicing Variation in OTC Deficiency of Mice and Man

Authors:
Rivera-Barahona A, Sánchez-Alcudia R, Viecelli HM, Rüfenacht V, Pérez B, Ugarte M, Häberle J, Thöny B, Desviat LR
Citation:
PLoS ONE. 2015;10(4):e0122966. doi:10.1371/journal.pone.0122966
Epub:
Not Epub
Abstract:
The spf/ash mouse model of ornithine transcarbamylase (OTC) deficiency, a severe urea cycle disorder, is caused by a mutation (...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122966
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Hep3B cells
Citation Extract:
Rivera-Barahona A, Sánchez-Alcudia R, Viecelli HM, Rüfenacht V, Pérez B, Ugarte M, Häberle J, Thöny B, Desviat LR. Functional Characterization of the spf/ash Splicing Variation in OTC Deficiency of Mice and Man. PLoS ONE. 2015;10(4):e0122966. doi:10.1371/journal.pone.0122966.

Dendrimer Conjugates for Light-activated Delivery of Antisense Oligonucleotides

Authors:
Yuan A, Hu Y, Ming X
Citation:
RSC Adv. 2015;{Epub ahead of print] doi:10.1039/C5RA04091D
Epub:
Yes
Abstract:
Therapeutic oligonucleotides, such as splice switching ONs (SSOs), provide opportunity for treating serious, life-threatening...
Link:
http://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra04091d#!divAbstract
Delivery Method:
nanoparticle with photointernalization
Organism or Cell Type:
cell culture: A375 melanoma cells
Citation Extract:
Yuan A, Hu Y, Ming X. Dendrimer Conjugates for Light-activated Delivery of Antisense Oligonucleotides. RSC Adv. 2015;{Epub ahead of print] doi:10.1039/C5RA04091D.

Incomplete splicing of neutrophil-specific genes affects neutrophil development in a zebrafish model of poikiloderma with neutropenia

Authors:
Patil P, Uechi T, Kenmochi N
Citation:
RNA Biol. 2015 Apr 3;12(4):426-434
Epub:
Not Epub
Abstract:
Poikiloderma with neutropenia (PN) is a rare inherited disorder characterized by poikiloderma, facial dysmorphism, pachyonychia...
Link:
http://www.tandfonline.com/doi/abs/10.1080/15476286.2015.1017240#.VSVHo-FtETY
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patil P, Uechi T, Kenmochi N. Incomplete splicing of neutrophil-specific genes affects neutrophil development in a zebrafish model of poikiloderma with neutropenia. RNA Biol. 2015 Apr 3;12(4):426-434.

Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation

Authors:
Zhang X, Cheong S-M, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X
Citation:
Dev Cell. 2015;32(6):719-30. doi:10.1016/j.devcel.2015.02.014
Epub:
Not Epub
Abstract:
Secreted Wnt morphogens are essential for embryogenesis and homeostasis and require a lipid/palmitoleoylate modification for...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807%2815%2900132-X
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Zhang X, Cheong S-M, Amado NG, Reis AH, MacDonald BT, Zebisch M, Jones EY, Abreu JG, He X. Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation. Dev Cell. 2015;32(6):719-30. doi:10.1016/j.devcel.2015.02.014.

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction

Authors:
Akizu N, Cantagrel V, Zaki MS, Al-Gazali L, Wang X, Rosti RO, Dikoglu E, Gelot AB, Rosti B, Vaux KK, Scott EM, Silhavy JL, Schroth J, Copeland B, Schaffer AE, Gordts PLSM, Esko JD, Buschman MD, Field SJ, Napolitano G, Abdel-Salam GM, Ozgul RK, Sagıroglu MS, Azam M, Ismail S, Aglan M, Selim L, Mahmoud IG, Abdel-Hadi S, Badawy AE, Sadek AA, Mojahedi F, Kayserili H, Masri A, Bastaki L, Temtamy S, Müller U, Desguerre I, Casanova J-L, Dursun A, Gunel M, Gabriel SB, de Lonlay P, Gleeson JG
Citation:
Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3256
Epub:
Yes
Abstract:
Pediatric-onset ataxias often present clinically as developmental delay and intellectual disability, with prominent cerebellar...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3256.html#abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Akizu N, Cantagrel V, Zaki MS, Al-Gazali L, Wang X, Rosti RO, Dikoglu E, Gelot AB, Rosti B, Vaux KK, Scott EM, Silhavy JL, Schroth J, Copeland B, Schaffer AE, Gordts PLSM, Esko JD, Buschman MD, Field SJ, Napolitano G, Abdel-Salam GM, Ozgul RK, Sagıroglu MS, Azam M, Ismail S, Aglan M, Selim L, Mahmoud IG, Abdel-Hadi S, Badawy AE, Sadek AA, Mojahedi F, Kayserili H, Masri A, Bastaki L, Temtamy S, Müller U, Desguerre I, Casanova J-L, Dursun A, Gunel M, Gabriel SB, de Lonlay P, Gleeson JG. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3256.

Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development

Authors:
Kurian L, Aguirre A, Sancho-Martinez I, Benner C, Hishida T, Nguyen TB, Reddy P, Nivet E, Krause MN, Nelles DA, Esteban CR, Campistol JM, Yeo GW, Belmonte JCI
Citation:
Circulation. 2015;131:1278-1290. doi:10.1161/CIRCULATIONAHA.114.013303
Epub:
Not Epub
Abstract:
Background—Long noncoding RNAs (lncRNAs) have emerged as critical epigenetic regulators with important functions in development...
Link:
https://circ.ahajournals.org/content/131/14/1278.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Kurian L, Aguirre A, Sancho-Martinez I, Benner C, Hishida T, Nguyen TB, Reddy P, Nivet E, Krause MN, Nelles DA, Esteban CR, Campistol JM, Yeo GW, Belmonte JCI. Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development. Circulation. 2015;131:1278-1290. doi:10.1161/CIRCULATIONAHA.114.013303 .

The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin

Authors:
Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A
Citation:
Development. 2015 Jan 1;142(1):174-84. doi: 10.1242/dev.112250
Epub:
Not Epub
Abstract:
Cilia are microtubule-based organelles that are present on most cells and are required for normal tissue development and...
Link:
http://dev.biologists.org/content/142/1/174, http://dev.biologists.org/content/142/8/1553.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish & Xenopus
Citation Extract:
Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A. The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin. Development. 2015 Jan 1;142(1):174-84. doi: 10.1242/dev.112250.

Knockdown of transcription factor forkhead box O3 (FOXO3) suppresses erythroid differentiation in human cells and zebrafish

Authors:
Wang H, Li Y, Wang S, Zhang Q, Zheng J, Yang Y, Qi H, Qu H, Zhang Z, Liu F, Fang X
Citation:
Biochem Biophys Res Commun. 2015 Apr 2. pii: S0006-291X(15)00594-X. doi: 10.1016/j.bbrc.2015.03.128. [Epub ahead of print]
Epub:
Yes
Abstract:
Our previous study on the dynamic transcriptomes activated during human erythropoiesis suggested that transcription factor...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X1500594X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang H, Li Y, Wang S, Zhang Q, Zheng J, Yang Y, Qi H, Qu H, Zhang Z, Liu F, Fang X. Knockdown of transcription factor forkhead box O3 (FOXO3) suppresses erythroid differentiation in human cells and zebrafish. Biochem Biophys Res Commun. 2015 Apr 2. pii: S0006-291X(15)00594-X. doi: 10.1016/j.bbrc.2015.03.128. [Epub ahead of print].

glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis

Authors:
Ye L, Robertson MA, Hesselson D, Stainier DYR, Anderson RM
Citation:
Development. 2015;142:1407-17. doi:10.1242/dev.117911
Epub:
Not Epub
Abstract:
The interconversion of cell lineages via transdifferentiation is an adaptive mode of tissue regeneration and an appealing...
Link:
http://dev.biologists.org/content/142/8/1407.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ye L, Robertson MA, Hesselson D, Stainier DYR, Anderson RM. glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis. Development. 2015;142:1407-17. doi:10.1242/dev.117911.

EBV noncoding RNA binds nascent RNA to drive host PAX5 to viral DNA

Authors:
Lee N, Moss WN, Yario TA, Steitz JA
Citation:
Cell. 2015 Feb 12;160(4):607-18. doi: 10.1016/j.cell.2015.01.015. Epub 2015 Feb 5
Epub:
Not Epub
Abstract:
EBER2 is an abundant nuclear noncoding RNA expressed by the Epstein-Barr virus (EBV). Probing its possible chromatin...
Link:
http://www.cell.com/cell/abstract/S0092-8674%2815%2900017-3
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: BJAB-B1 cells
Citation Extract:
Lee N, Moss WN, Yario TA, Steitz JA. EBV noncoding RNA binds nascent RNA to drive host PAX5 to viral DNA. Cell. 2015 Feb 12;160(4):607-18. doi: 10.1016/j.cell.2015.01.015. Epub 2015 Feb 5.

Pages