You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Ultrasensitive detection of exosomal miRNA with PMO-graphene quantum dots-functionalized field-effect transistor biosensor

Authors:
Li K, Tu J, Zhang Y, Jin D, Li T, Li J, Ni W, Xiao MM, Zhang ZY, Zhang GJ
Citation:
iScience. 2022 Jun 3;25(7):104522. doi: 10.1016/j.isci.2022.104522. eCollection 2022 Jul 15.
Epub:
Not Epub
Abstract:
Compared with the conventional DNA probe immobilization on the planar surface, nanoparticles-based DNA probes enable more RNA...
Link:
https://www.cell.com/iscience/fulltext/S2589-0042(22)00793-3
Citation Extract:
Li K, Tu J, Zhang Y, Jin D, Li T, Li J, Ni W, Xiao MM, Zhang ZY, Zhang GJ. Ultrasensitive detection of exosomal miRNA with PMO-graphene quantum dots-functionalized field-effect transistor biosensor. iScience. 2022 Jun 3;25(7):104522. doi: 10.1016/j.isci.2022.104522. eCollection 2022 Jul 15..

CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development

Authors:
Klaus A, Clapes T, Yvernogeau L, Basu S, Weijts B, Maas J, Smal I, Galjart N, Robin C
Citation:
Cell Rep. 2022 Jun 14;39(11):110957. doi: 10.1016/j.celrep.2022.110957
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) express a large variety of cell surface receptors that are associated with acquisition of self-...
Link:
https://www.cell.com/cell-reports/pdfExtended/S2211-1247(22)00739-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Klaus A, Clapes T, Yvernogeau L, Basu S, Weijts B, Maas J, Smal I, Galjart N, Robin C. CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development. Cell Rep. 2022 Jun 14;39(11):110957. doi: 10.1016/j.celrep.2022.110957.

Shoc2 controls ERK1/2-driven neural crest development by balancing components of the extracellular matrix

Authors:
Norcross RG, Abdelmoti L, Rouchka EC, Andreeva K, Tussey O, Landestoy D, Galperin E
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.06.13.495941
Epub:
Not Epub
Abstract:
The extracellular signal-regulated kinase (ERK1/2) pathway is essential in embryonic development. The scaffold protein Shoc2 is...
Link:
https://www.biorxiv.org/content/10.1101/2022.06.13.495941v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Norcross RG, Abdelmoti L, Rouchka EC, Andreeva K, Tussey O, Landestoy D, Galperin E. Shoc2 controls ERK1/2-driven neural crest development by balancing components of the extracellular matrix. bioRxiv. 2022;[preprint] doi:10.1101/2022.06.13.495941 .

MNK2 deficiency potentiates β-cell regeneration via translational regulation

Authors:
Karampelias C, Watt K, Mattsson CL, Ruiz ÁF, Rezanejad H, Mi J, Liu X, Chu L, Locasale JW, Korbutt GS, Rovira M, Larsson O, Andersson O
Citation:
Nat Chem Biol. 2022 Jun 13. doi: 10.1038/s41589-022-01047-x. Online ahead of print
Epub:
Not Epub
Abstract:
Regenerating pancreatic β-cells is a potential curative approach for diabetes. We previously identified the small molecule...
Link:
https://www.nature.com/articles/s41589-022-01047-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Karampelias C, Watt K, Mattsson CL, Ruiz ÁF, Rezanejad H, Mi J, Liu X, Chu L, Locasale JW, Korbutt GS, Rovira M, Larsson O, Andersson O. MNK2 deficiency potentiates β-cell regeneration via translational regulation. Nat Chem Biol. 2022 Jun 13. doi: 10.1038/s41589-022-01047-x. Online ahead of print.

Downregulation of Yap1 During Limb Regeneration Results in Defective Bone Formation in Axolotl

Authors:
Bay S, Öztürk G, Emekli N, Demircan T
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.06.12.495807
Epub:
Not Epub
Abstract:
The Hippo pathway plays an imperative role in cellular processes such as differentiation, regeneration, cell migration, organ...
Link:
https://www.biorxiv.org/content/10.1101/2022.06.12.495807v1
Delivery Method:
injection then electroporation
Organism or Cell Type:
Ambystoma mexicanum (axlotl)
Citation Extract:
Bay S, Öztürk G, Emekli N, Demircan T. Downregulation of Yap1 During Limb Regeneration Results in Defective Bone Formation in Axolotl. bioRxiv. 2022;[preprint] doi:10.1101/2022.06.12.495807.

Helix-Stabilized Cell-Penetrating Peptides for Delivery of Antisense Morpholino Oligomers: Relationships among Helicity, Cellular Uptake, and Antisense Activity

Authors:
Takada H, Tsuchiya K, Demizu Y
Citation:
Bioconjug Chem. 2022 Jun 23. doi: 10.1021/acs.bioconjchem.2c00199. Online ahead of print
Epub:
Yes
Abstract:
The secondary structures of cell-penetrating peptides (CPPs) influence their properties including their cell-membrane...
Link:
https://pubs.acs.org/doi/10.1021/acs.bioconjchem.2c00199
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa 705
Citation Extract:
Takada H, Tsuchiya K, Demizu Y. Helix-Stabilized Cell-Penetrating Peptides for Delivery of Antisense Morpholino Oligomers: Relationships among Helicity, Cellular Uptake, and Antisense Activity. Bioconjug Chem. 2022 Jun 23. doi: 10.1021/acs.bioconjchem.2c00199. Online ahead of print.

Phagosomal Acidification Is Required to Kill Streptococcus pneumoniae in a Zebrafish Model

Authors:
Prajsnar TK, Michno BJ, Pooranachandran N, Fenton AK, Mitchell TJ, Dockrell DH, Renshaw SA
Citation:
Cell Microbiol. 2022;2022:9429516. doi:10.1155/2022/9429516
Epub:
Not Epub
Abstract:
Streptococcus pneumoniae (the pneumococcus) is a major human pathogen causing invasive disease, including community-acquired...
Link:
https://www.hindawi.com/journals/cmi/2022/9429516/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prajsnar TK, Michno BJ, Pooranachandran N, Fenton AK, Mitchell TJ, Dockrell DH, Renshaw SA. Phagosomal Acidification Is Required to Kill Streptococcus pneumoniae in a Zebrafish Model. Cell Microbiol. 2022;2022:9429516. doi:10.1155/2022/9429516.

Slit-Robo signalling establishes a Sphingosine-1-phosphate gradient to polarise fin mesenchyme

Authors:
Mahabaleshwar H, Asharani PV, Loo TY, Koh SY, Pitman MR, Kwok S, Ma J, Hu B, Lin F, Li Lok X, Pitson SM, Saunders TE, Carney TJ
Citation:
EMBO Rep. 2022 Jun 9:e54464. doi: 10.15252/embr.202154464. Online ahead of print
Epub:
Not Epub
Abstract:
Immigration of mesenchymal cells into the growing fin and limb buds drives distal outgrowth, with subsequent tensile forces...
Link:
https://www.embopress.org/doi/abs/10.15252/embr.202154464
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahabaleshwar H, Asharani PV, Loo TY, Koh SY, Pitman MR, Kwok S, Ma J, Hu B, Lin F, Li Lok X, Pitson SM, Saunders TE, Carney TJ. Slit-Robo signalling establishes a Sphingosine-1-phosphate gradient to polarise fin mesenchyme. EMBO Rep. 2022 Jun 9:e54464. doi: 10.15252/embr.202154464. Online ahead of print.

N6-methyladenosine-modified circRNA RERE modulates osteoarthritis by regulating β-catenin ubiquitination and degradation

Authors:
Liu Y, Yang Y, Lin Y, Wei B, Hu X, Xu L, Zhang W, Lu J
Citation:
Cell Prolif. 2023 Jan;56(1):e13297. doi: 10.1111/cpr.13297. Epub 2022 Jun 22. PMID: 35733354; PMCID: PMC9816929
Epub:
Yes
Abstract:
Objectives: N6 -methyladenosine (m6A) is one of the most abundant internal RNA modifications. We investigated the role of m6A-...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9816929/
Delivery Method:
Endo-Porter, Vivo-Morpholino
Organism or Cell Type:
cell culture: primary human chondrocytes, mice
Citation Extract:
Liu Y, Yang Y, Lin Y, Wei B, Hu X, Xu L, Zhang W, Lu J. N6-methyladenosine-modified circRNA RERE modulates osteoarthritis by regulating β-catenin ubiquitination and degradation. Cell Prolif. 2023 Jan;56(1):e13297. doi: 10.1111/cpr.13297. Epub 2022 Jun 22. PMID: 35733354; PMCID: PMC9816929.

Expression and development of TARP γ-4 in embryonic zebrafish

Authors:
Ahmed KT, Amin MR, Razmara P, Roy B, Cai R, Tang J, Chen XZ, Ali DW
Citation:
Dev Neurosci. 2022 Jun 21. doi: 10.1159/000525578. Online ahead of print
Epub:
Not Epub
Abstract:
Fast excitatory synaptic transmission in the CNS is mediated by the neurotransmitter glutamate, binding to and activating AMPA...
Link:
https://www.karger.com/Article/Abstract/525578
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahmed KT, Amin MR, Razmara P, Roy B, Cai R, Tang J, Chen XZ, Ali DW. Expression and development of TARP γ-4 in embryonic zebrafish. Dev Neurosci. 2022 Jun 21. doi: 10.1159/000525578. Online ahead of print.

Pages