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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Strength of interactions in the Notch gene regulatory network determines patterning and fate in the notochord

Authors:
Sánchez-Iranzo H, Halavatyi A, Diz-Muñoz A
Citation:
eLife. 2022;11:e75429. doi:10.7554/eLife.75429
Epub:
Not Epub
Abstract:
Development of multicellular organisms requires the generation of gene expression patterns that determines cell fate and organ...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sánchez-Iranzo H, Halavatyi A, Diz-Muñoz A. Strength of interactions in the Notch gene regulatory network determines patterning and fate in the notochord. eLife. 2022;11:e75429. doi:10.7554/eLife.75429.

Brain Dp140 alters glutamatergic transmission and social behaviour in the mdx52 mouse model of Duchenne muscular dystrophy

Authors:
Hashimoto Y, Kuniishi H, Sakai K, Fukushima Y, Du X, Yamashiro K, Hori K, Imamura M, Hoshino M, Yamada M, Araki T, Sakagami H, Takeda S, Itaka K, Ichinohe N, Muntoni F, Sekiguchi M, Aoki Y
Citation:
Prog Neurobiol. 2022 May 30:102288. doi: 10.1016/j.pneurobio.2022.102288. Online ahead of print
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a muscle disorder caused by DMD mutations and is characterized by neurobehavioural...
Delivery Method:
intracerebroventricular (i.c.v.) infusion
Organism or Cell Type:
mice
Citation Extract:
Hashimoto Y, Kuniishi H, Sakai K, Fukushima Y, Du X, Yamashiro K, Hori K, Imamura M, Hoshino M, Yamada M, Araki T, Sakagami H, Takeda S, Itaka K, Ichinohe N, Muntoni F, Sekiguchi M, Aoki Y. Brain Dp140 alters glutamatergic transmission and social behaviour in the mdx52 mouse model of Duchenne muscular dystrophy. Prog Neurobiol. 2022 May 30:102288. doi: 10.1016/j.pneurobio.2022.102288. Online ahead of print.

Perfluorooctane Sulfonamide (PFOSA) Induces Cardiotoxicity via Aryl Hydrocarbon Receptor Activation in Zebrafish

Authors:
Chen H, Qiu W, Yang X, Chen F, Chen J, Tang L, Zhong H, Magnuson JT, Zheng C, Xu EG
Citation:
Environ Sci Technol. 2022 Jun 2. doi: 10.1021/acs.est.1c08875. Online ahead of print
Epub:
Not Epub
Abstract:
Perfluorooctane sulfonamide (PFOSA), a precursor of perfluorooctanesulfonate (PFOS), is widely used during industrial processes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen H, Qiu W, Yang X, Chen F, Chen J, Tang L, Zhong H, Magnuson JT, Zheng C, Xu EG. Perfluorooctane Sulfonamide (PFOSA) Induces Cardiotoxicity via Aryl Hydrocarbon Receptor Activation in Zebrafish. Environ Sci Technol. 2022 Jun 2. doi: 10.1021/acs.est.1c08875. Online ahead of print.

Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue

Authors:
Scripture-Adams DD, Chesmore KN, Barthélémy F, Wang RT, Nieves-Rodriguez S, Wang DW, Mokhonova EI, Douine ED, Wan J, Little I, Rabichow LN, Nelson SF, Miceli MC
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.05.31.494197
Epub:
Not Epub
Abstract:
In Duchenne muscular dystrophy, dystrophin loss leads to chronic muscle damage, dysregulation of repair, fibro-fatty...
Organism or Cell Type:
mice
Citation Extract:
Scripture-Adams DD, Chesmore KN, Barthélémy F, Wang RT, Nieves-Rodriguez S, Wang DW, Mokhonova EI, Douine ED, Wan J, Little I, Rabichow LN, Nelson SF, Miceli MC. Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue. bioRxiv. 2022;[preprint] doi:10.1101/2022.05.31.494197 .

Cholesterol Accumulation in Livers of Indian Medaka, Oryzias dancena, Acclimated to Fresh Water and Seawater

Authors:
Ranasinghe N, Lin C-H, Lee T-H
Citation:
Front Mar Sci. 2022;9:{Epub] doi:10.3389/fmars.2022.891706
Epub:
Yes
Abstract:
Sterol regulatory-element binding proteins (SREBPs), sirtuin (SIRT1), and liver X receptor α (LXRα) play important roles in...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Oryzias dancena (Indian medaka)
Citation Extract:
Ranasinghe N, Lin C-H, Lee T-H. Cholesterol Accumulation in Livers of Indian Medaka, Oryzias dancena, Acclimated to Fresh Water and Seawater. Front Mar Sci. 2022;9:{Epub] doi:10.3389/fmars.2022.891706.

Identification of Novel Vascular Genes Downstream of Islet2 and Nr2f1b Transcription Factors

Authors:
Li R-F, Wang Y-S, Lu F-I, Huang Y-S, Chiu C-C, Tai M-H, Wu C-Y
Citation:
Biomedicines. 2022;10(6):1261. doi:/10.3390/biomedicines10061261
Epub:
Not Epub
Abstract:
The genetic regulation of vascular development is not elucidated completely. We previously characterized the transcription...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li R-F, Wang Y-S, Lu F-I, Huang Y-S, Chiu C-C, Tai M-H, Wu C-Y. Identification of Novel Vascular Genes Downstream of Islet2 and Nr2f1b Transcription Factors. Biomedicines. 2022;10(6):1261. doi:/10.3390/biomedicines10061261.

A Strategy for Gene Knockdown in Dinoflagellates

Authors:
Judd M, Place AR
Citation:
Microorganisms. 2022;10:1131. doi:10.3390/microorganisms10061131
Epub:
Not Epub
Abstract:
Dinoflagellates are unicellular protists that display unusual nuclear features such as large genomes, condensed chromosomes and...
Delivery Method:
Endo-Porter
Organism or Cell Type:
Amphidinium carterae (dinoflagellate)
Citation Extract:
Judd M, Place AR. A Strategy for Gene Knockdown in Dinoflagellates. Microorganisms. 2022;10:1131. doi:10.3390/microorganisms10061131.

Dicer1 is required for pigment cell and craniofacial development in zebrafish

Authors:
Weiner AMJ, Scampoli NL, Steeman TJ, Dooley CM, Busch-Nentwich EM, Kelsh RN, Calcaterra NB
Citation:
Biochim Biophys Acta Gene Regul Mech. 2019 Apr;1862(4):472-485. doi: 10.1016/j.bbagrm.2019.02.005. Epub 2019 Mar 3
Epub:
Not Epub
Abstract:
The multidomain RNase III endoribonuclease DICER is required for the generation of most functional microRNAs (miRNAs). Loss of...
Organism or Cell Type:
zebrafish
Citation Extract:
Weiner AMJ, Scampoli NL, Steeman TJ, Dooley CM, Busch-Nentwich EM, Kelsh RN, Calcaterra NB. Dicer1 is required for pigment cell and craniofacial development in zebrafish. Biochim Biophys Acta Gene Regul Mech. 2019 Apr;1862(4):472-485. doi: 10.1016/j.bbagrm.2019.02.005. Epub 2019 Mar 3.

Adgrg6/Gpr126 is required for myocardial Notch activity and N-cadherin localization to attain trabecular identity

Authors:
Srivastava S, Gunawan F, Gentile A, Petersen SC, Stainier DYR, Engel FB
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.05.27.493401
Epub:
Not Epub
Abstract:
How adhesion G protein-coupled receptors (aGPCRs) control development remains unclear. The aGPCR Adgrg6/Gpr126 has been...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Srivastava S, Gunawan F, Gentile A, Petersen SC, Stainier DYR, Engel FB. Adgrg6/Gpr126 is required for myocardial Notch activity and N-cadherin localization to attain trabecular identity. bioRxiv. 2022;[preprint] doi:10.1101/2022.05.27.493401.

Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery

Authors:
Zhang Y, Heylen L, Partoens M, Mills JD, Kaminski RM, Godard P, Gillard M, de Witte PAM, Siekierska A
Citation:
Front Mol Neurosci. 2022;15:[Epub] doi:10.3389/fnmol.2022.881933
Epub:
Yes
Abstract:
Synaptic vesicle glycoprotein 2A (SV2A) regulates action potential-dependent neurotransmitter release and is commonly known as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Heylen L, Partoens M, Mills JD, Kaminski RM, Godard P, Gillard M, de Witte PAM, Siekierska A. Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery. Front Mol Neurosci. 2022;15:[Epub] doi:10.3389/fnmol.2022.881933.

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