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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12160 scientific papers returned from the database with the search filters currently being used below.

Maternal and zygotic contributions to H3K4me1 chromatin marking during germ layer formation

Authors:
Paraiso KD, Blitz IL, Cho KWY
Citation:
Dev Biol. 2025 Feb;518:8-19. doi: 10.1016/j.ydbio.2024.11.006. Epub 2024 Nov 15. PMID: 39550025; PMCID: PMC11796633
Epub:
Not Epub
Abstract:
An early step in triploblastic embryo differentiation is the formation of the three germ layers. Maternal pioneer transcription...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160624002586
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Paraiso KD, Blitz IL, Cho KWY. Maternal and zygotic contributions to H3K4me1 chromatin marking during germ layer formation. Dev Biol. 2025 Feb;518:8-19. doi: 10.1016/j.ydbio.2024.11.006. Epub 2024 Nov 15. PMID: 39550025; PMCID: PMC11796633.

Sox8 remodels the cranial ectoderm to generate the ear

Authors:
Buzzi AL, Chen J, Thiery A, Delile J, Streit A
Citation:
Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2118938119. doi: 10.1073/pnas.2118938119. Epub 2022 Jul 8. PMID: 35867760; PMCID: PMC9282420
Epub:
Not Epub
Abstract:
The vertebrate inner ear arises from a pool of progenitors with the potential to contribute to all the sense organs and cranial...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9282420/
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Buzzi AL, Chen J, Thiery A, Delile J, Streit A. Sox8 remodels the cranial ectoderm to generate the ear. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2118938119. doi: 10.1073/pnas.2118938119. Epub 2022 Jul 8. PMID: 35867760; PMCID: PMC9282420.

Involvement of Huntingtin in Development and Ciliary Beating Regulation of Larvae of the Sea Urchin, Hemicentrotus pulcherrimus

Authors:
Katow H, Katow T, Yoshida H, Kiyomoto M
Citation:
Int J Mol Sci. 2021;22(10):5116. doi:10.3390/ijms22105116
Epub:
Not Epub
Abstract:
The multiple functions of the wild type Huntington’s disease protein of the sea urchin Hemicentrotus pulcherrimus (Hp-Htt) have...
Link:
https://www.mdpi.com/1422-0067/22/10/5116/htm
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Katow H, Katow T, Yoshida H, Kiyomoto M. Involvement of Huntingtin in Development and Ciliary Beating Regulation of Larvae of the Sea Urchin, Hemicentrotus pulcherrimus. Int J Mol Sci. 2021;22(10):5116. doi:10.3390/ijms22105116.

Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia

Authors:
Falcao MAP, Walker COB, Disner GR, Batista-Filho J, Soares ABS, Balan-Lima L, Lima C, Lopes-Ferreira M
Citation:
Fish Shellfish Immunol. 2021;[Epub] doi:10.1016/j.fsi.2021.04.029
Epub:
Yes
Abstract:
Our recent data show the valuable potential of TnP for the development of a new and safe anti-inflammatory drug due to its...
Link:
https://www.sciencedirect.com/science/article/pii/S1050464821001194
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Falcao MAP, Walker COB, Disner GR, Batista-Filho J, Soares ABS, Balan-Lima L, Lima C, Lopes-Ferreira M. Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia. Fish Shellfish Immunol. 2021;[Epub] doi:10.1016/j.fsi.2021.04.029.

Identification of Zebrafish Ortholog for Human Coagulation Factor IX and its Age-dependent Expression

Authors:
Iyer N, Al Qaryoute A, Kacham M, Jagadeeswaran P
Citation:
J Thromb Haemost. 2021 May 11. doi: 10.1111/jth.15365. Online ahead of print
Epub:
Yes
Abstract:
Background: Coagulation factor IX (FIX) is a serine protease zymogen involved in the intrinsic blood coagulation pathway, and...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/jth.15365
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Iyer N, Al Qaryoute A, Kacham M, Jagadeeswaran P. Identification of Zebrafish Ortholog for Human Coagulation Factor IX and its Age-dependent Expression. J Thromb Haemost. 2021 May 11. doi: 10.1111/jth.15365. Online ahead of print.

The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus

Authors:
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y
Citation:
Proc Nat Acad Sci USA. 2021;118(20):e2100342118. doi:10.1073/pnas.2100342118
Epub:
Not Epub
Abstract:
Fibroblast growth factor (FGF)/extracellular signal-regulated kinase (ERK) signaling plays a crucial role in anterior–posterior...
Link:
https://www.pnas.org/content/118/20/e2100342118
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y. The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. Proc Nat Acad Sci USA. 2021;118(20):e2100342118. doi:10.1073/pnas.2100342118.

RNA m6A methyltransferase Mettl3 regulates spatial neural patterning in Xenopus

Authors:
Kim H, Jang S
Citation:
Mol Cell Biol. 2021 May 10:MCB.00104-21. doi: 10.1128/MCB.00104-21. Online ahead of print
Epub:
Yes
Abstract:
N6-methyladenosine (m6A) is the most prevalent internal RNA modification, and has a widespread impact on mRNA stability and...
Link:
https://mcb.asm.org/content/early/2021/05/04/MCB.00104-21
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim H, Jang S. RNA m6A methyltransferase Mettl3 regulates spatial neural patterning in Xenopus. Mol Cell Biol. 2021 May 10:MCB.00104-21. doi: 10.1128/MCB.00104-21. Online ahead of print.

Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia

Authors:
Wiessner M, Maroofian R, Ni M-Y, Pedroni A, Müller JS, Stucka R, Beetz C, Efthymiou S, Santorelli FM, Alfares AA, Zhu C, Uhrova MA, Alehabib E, Bakhtiari S, Janecke AR, Otero MG, Chen JYH, Peterson JT, Strom TM, De JP, Deconinck T, De Ridder W, De Winter J, Pasquariello R, Ricca I,Alfadhel M, van de Warrenburg BP, Portier R, Bergmann C, Ghasemi FS,Jin SC, Bilguvar K, Hamed S, Abdelhameed M, Haridy NA, Maqbool S, Rahman F, Anwar N, Carmichael J, Pagnamenta A, Wood NW, Tran Mau-Them F, Haack T, Genomics England Research Consortium PREPARE network, Di Rocco M, <authors deleted - database limit> Shamseldin H, Al Tala S, Rezazadeh VJ, Najafi M, Deschner S, Gläser D, Hüttel W, Kruer MC, Kamsteeg E-J, Takiyama Y, Züchner S, Baets J, Synofzik M, Schüle R, Horvath R, Houlden H, Bartesaghi L, Lee H-J, Ampatzis K, Pierson TM, Senderek J
Citation:
Brain. 2021;[Epub] doi:10.1093/brain/awab041
Epub:
Not Epub
Abstract:
Human 4-hydroxyphenylpyruvate dioxygenase-like (HPDL) is a putative iron-containing non-heme oxygenase of unknown specificity...
Link:
https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab041/6273093
Organism or Cell Type:
zebrafish
Citation Extract:
Wiessner M, Maroofian R, Ni M-Y, Pedroni A, Müller JS, Stucka R, Beetz C, Efthymiou S, Santorelli FM, Alfares AA, Zhu C, Uhrova MA, Alehabib E, Bakhtiari S, Janecke AR, Otero MG, Chen JYH, Peterson JT, Strom TM, De JP, Deconinck T, De Ridder W, De Winter J, Pasquariello R, Ricca I,Alfadhel M, van de Warrenburg BP, Portier R, Bergmann C, Ghasemi FS,Jin SC, Bilguvar K, Hamed S, Abdelhameed M, Haridy NA, Maqbool S, Rahman F, Anwar N, Carmichael J, Pagnamenta A, Wood NW, Tran Mau-Them F, Haack T, Genomics England Research Consortium PREPARE network, Di Rocco M, <authors deleted - database limit> Shamseldin H, Al Tala S, Rezazadeh VJ, Najafi M, Deschner S, Gläser D, Hüttel W, Kruer MC, Kamsteeg E-J, Takiyama Y, Züchner S, Baets J, Synofzik M, Schüle R, Horvath R, Houlden H, Bartesaghi L, Lee H-J, Ampatzis K, Pierson TM, Senderek J. Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia. Brain. 2021;[Epub] doi:10.1093/brain/awab041.

Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo

Authors:
Molina MD, Lepage T
Citation:
Curr Top Dev Biol. 2020;140:283-316. doi: 10.1016/bs.ctdb.2019.10.007. Epub 2019 Nov 22
Epub:
Not Epub
Abstract:
Specification of the main axes of polarity of the embryo is an essential process during embryonic development. In many species...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0070215319300821
Organism or Cell Type:
sea urchin
Citation Extract:
Molina MD, Lepage T. Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo. Curr Top Dev Biol. 2020;140:283-316. doi: 10.1016/bs.ctdb.2019.10.007. Epub 2019 Nov 22.

Frizzled3 inhibits Vangl2-Prickle3 association to establish planar cell polarity in the vertebrate neural plate

Authors:
Chuykin I, Itoh K, Kim K, Sokol SY
Citation:
J Cell Sci. 2021 Dec 15;134(24):jcs258864. doi: 10.1242/jcs.258864. Epub 2021 Dec 15. PMID: 34806749; PMCID: PMC8729781
Epub:
Not Epub
Abstract:
The orientation of epithelial cells in the plane of the tissue, known as planar cell polarity (PCP), is regulated by...
Link:
https://journals.biologists.com/jcs/article/134/24/jcs258864/273708/Frizzled3-inhibits-Vangl2-Prickle3-association-to
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chuykin I, Itoh K, Kim K, Sokol SY. Frizzled3 inhibits Vangl2-Prickle3 association to establish planar cell polarity in the vertebrate neural plate. J Cell Sci. 2021 Dec 15;134(24):jcs258864. doi: 10.1242/jcs.258864. Epub 2021 Dec 15. PMID: 34806749; PMCID: PMC8729781.

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