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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12161 scientific papers returned from the database with the search filters currently being used below.
There are 12161 scientific papers returned from the database with the search filters currently being used below.
X-linked cellular mosaicism underlies age-dependent occurrence of seizure-like events in mouse models of CDKL5 deficiency disorder
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Citation:
Neurobiol Dis. 2021 Jan;148:105176. doi: 10.1016/j.nbd.2020.105176. Epub 2020 Nov 13. PMID: 33197557; PMCID: PMC7856307 Epub:
Not Epub Abstract:
CDKL5 deficiency disorder (CDD) is an infantile, epileptic encephalopathy presenting with early-onset seizures, intellectual... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Terzic B, Cui Y, Edmondson AC, Tang S, Sarmiento N, Zaitseva D, Marsh ED, Coulter DA, Zhou Z. X-linked cellular mosaicism underlies age-dependent occurrence of seizure-like events in mouse models of CDKL5 deficiency disorder. Neurobiol Dis. 2021 Jan;148:105176. doi: 10.1016/j.nbd.2020.105176. Epub 2020 Nov 13. PMID: 33197557; PMCID: PMC7856307. |
Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder
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Citation:
Front Cell Infect Microbiol. 2022 Mar 11;12:790851. doi: 10.3389/fcimb.2022.790851. PMID: 35360100; PMCID: PMC8963489. Epub:
Not Epub Abstract:
Animal models are essential to understanding COVID-19 pathophysiology and for preclinical assessment of drugs and other... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Laghi V, Rezelj V, Boucontet L, Frétaud M, Da Costa B, Boudinot P, Salinas I, Lutfalla G, Vignuzzi M, Levraud JP. Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder. Front Cell Infect Microbiol. 2022 Mar 11;12:790851. doi: 10.3389/fcimb.2022.790851. PMID: 35360100; PMCID: PMC8963489.. |
Hemodynamic Forces Regulate Cardiac Regeneration-Responsive Enhancer Activity during Ventricle Regeneration
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Citation:
Int J Mol Sci. 2021;22(8):3945. doi:10.3390/ijms22083945 Epub:
Not Epub Abstract:
Cardiac regenerative capacity varies widely among vertebrates. Zebrafish can robustly regenerate injured hearts and are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Geng F, Ma J, Li X, Hu Z, Zhang R. Hemodynamic Forces Regulate Cardiac Regeneration-Responsive Enhancer Activity during Ventricle Regeneration. Int J Mol Sci. 2021;22(8):3945. doi:10.3390/ijms22083945. |
Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis
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Citation:
Proc Nat Acad Sci USA. 2021;118(15):e2021210118. doi:10.1073/pnas.2021210118 Epub:
Not Epub Abstract:
Animal cytokinesis ends with the formation of a thin intercellular membrane bridge that connects the two newly formed sibling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N. Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis. Proc Nat Acad Sci USA. 2021;118(15):e2021210118. doi:10.1073/pnas.2021210118. |
Zebrafish modeling mimics developmental phenotype of patients with RAPGEF1 mutation
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Citation:
Clin Genet. 2021 Apr 9. doi: 10.1111/cge.13965. Online ahead of print Epub:
Yes Abstract:
RAPGEF1 is a guanine nucleotide exchange factor responsible for transmitting extracellular signals to the Ras family of GTPase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li N, Zhou P, Yang M, Fang X, Krämer N, Mughal TA, Abbasi AA, Yang Y, Kaindl AM, Hu H. Zebrafish modeling mimics developmental phenotype of patients with RAPGEF1 mutation. Clin Genet. 2021 Apr 9. doi: 10.1111/cge.13965. Online ahead of print. |
Endothelial struts enable the generation of large lumenized blood vessels de novo
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Citation:
Nat Cell Biol. 2021;23(4):322-329. doi:10.1038/s41556-021-00664-3 Epub:
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De novo blood vessel formation occurs through coalescence of endothelial cells (ECs) into a cord-like structure, followed by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D. Endothelial struts enable the generation of large lumenized blood vessels de novo. Nat Cell Biol. 2021;23(4):322-329. doi:10.1038/s41556-021-00664-3. |
BMP heterodimers signal via distinct type I receptor class functions
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Citation:
Proc Nat Acad Sci USA. 2021;118(15):e2017952118. doi:10.1073/pnas.2017952118 Epub:
Not Epub Abstract:
Heterodimeric TGF-β ligands outperform homodimers in a variety of developmental, cell culture, and therapeutic contexts;... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tajer B, Dutko JA, Little SC, Mullins MC. BMP heterodimers signal via distinct type I receptor class functions. Proc Nat Acad Sci USA. 2021;118(15):e2017952118. doi:10.1073/pnas.2017952118. |
Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction
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Citation:
Nat Comm. 2021;12(1):2103. doi:10.1038/s41467-021-22062-x Epub:
Not Epub Abstract:
Mitochondrial diseases impair oxidative phosphorylation and ATP production, while effective treatment is still lacking.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Peruzzo R, Corrà S, Costa R, Brischigliaro M, Varanita T, Biasutto L, Rampazzo C, Ghezzi D, Leanza L, Zoratti M, Zeviani M, De Pittà C, Viscomi C, Costa R, Szabò I. Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction. Nat Comm. 2021;12(1):2103. doi:10.1038/s41467-021-22062-x. |
Human disease-associated extracellular matrix orthologs ECM3 and QBRICK regulate primary mesenchymal cell migration in sea urchin embryos
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Citation:
Exp Anim. 2021 Apr 6. doi: 10.1538/expanim.21-0001. Online ahead of print Epub:
Yes Abstract:
Sea urchin embryos have been one of model organisms to investigate cellular behaviors because of their simple cell composition... Delivery Method:
microinjection Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Kiyozumi D, Yaguchi S, Yaguchi J, Yamazaki A, Sekiguchi K. Human disease-associated extracellular matrix orthologs ECM3 and QBRICK regulate primary mesenchymal cell migration in sea urchin embryos. Exp Anim. 2021 Apr 6. doi: 10.1538/expanim.21-0001. Online ahead of print. |
Kapd Is Essential for Specification of the Dopaminergic Neurogenesis in Zebrafish Embryos
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Citation:
Mol Cells. 2021 Apr 6. doi: 10.14348/molcells.2021.0005. Online ahead of print Epub:
Yes Abstract:
To define novel networks of Parkinson's disease (PD) pathogenesis, the substantia nigra pars compacta of A53T mice, where... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jung J, Kim E, Rhee M. Kapd Is Essential for Specification of the Dopaminergic Neurogenesis in Zebrafish Embryos. Mol Cells. 2021 Apr 6. doi: 10.14348/molcells.2021.0005. Online ahead of print. |