You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

CITK modulates BRCA1 recruitment at DNA double strand breaks sites through HDAC6

Authors:
Iegiani G, Pallavicini G, Pezzotta A, Brix A, Ferraro A, Gai M, Boda E, Bielas SL, Pistocchi A, Di Cunto F
Citation:
Cell Death Dis. 2025 Apr 20;16(1):320. doi: 10.1038/s41419-025-07655-4. PMID: 40254670; PMCID: PMC12009987
Epub:
Not Epub
Abstract:
Citron Kinase (CITK) is a protein encoded by the CIT gene, whose pathogenic variants underlie microcephalic phenotypes that...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12009987/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iegiani G, Pallavicini G, Pezzotta A, Brix A, Ferraro A, Gai M, Boda E, Bielas SL, Pistocchi A, Di Cunto F. CITK modulates BRCA1 recruitment at DNA double strand breaks sites through HDAC6. Cell Death Dis. 2025 Apr 20;16(1):320. doi: 10.1038/s41419-025-07655-4. PMID: 40254670; PMCID: PMC12009987.

Microglia-Derived IL-6 Promotes Müller Glia Reprogramming and Proliferation in Zebrafish Retina Regeneration

Authors:
Xu J, Li Y, Li X, Tan X, Liu L, Cao L, Xu H
Citation:
Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):67. doi: 10.1167/iovs.66.4.67. PMID: 40266594; PMCID: PMC12025339
Epub:
Not Epub
Abstract:
Purpose: Inflammation activates the Jak1-Stat3 signaling pathway in zebrafish Müller glia (MG), leading to their status...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12025339/
Delivery Method:
intravitreal injection & electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Xu J, Li Y, Li X, Tan X, Liu L, Cao L, Xu H. Microglia-Derived IL-6 Promotes Müller Glia Reprogramming and Proliferation in Zebrafish Retina Regeneration. Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):67. doi: 10.1167/iovs.66.4.67. PMID: 40266594; PMCID: PMC12025339.

Role of different Lyl1 transcripts in zebrafish primitive hematopoiesis

Authors:
Lin JH, Yang TS, Zhang WQ, Liu W
Citation:
Yi Chuan. 2025 May;47(5):573-588. doi: 10.16288/j.yczz.24-288. PMID: 40287790
Epub:
Not Epub
Abstract:
Primitive hematopoiesis is a crucial process in the organism, responsible for the transportation of oxygen and nutrients during...
Link:
10.16288/j.yczz.24-288
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin JH, Yang TS, Zhang WQ, Liu W. Role of different Lyl1 transcripts in zebrafish primitive hematopoiesis. Yi Chuan. 2025 May;47(5):573-588. doi: 10.16288/j.yczz.24-288. PMID: 40287790.

Two-component T-cell immunotherapy enables antigen pre-targeting to reduce cytokine release without forfeiting efficacy

Authors:
Gambles MT, Kendell I, Li J, Spainhower K, Sborov D, Owen S, Stark A, Bearss D, Yang J, Kopeček J
Citation:
Nanomedicine. 2025 Apr 30;67:102825. doi: 10.1016/j.nano.2025.102825. Epub ahead of print. PMID: 40316226
Epub:
Not Epub
Abstract:
Contemporary T-cell immunotherapies, despite impressive targeting precision, are hindered by aberrant cytokine release and...
Link:
https://www.sciencedirect.com/science/article/pii/S1549963425000255
Delivery Method:
Fab-linked; mice: intravenous (i.v.) injection
Organism or Cell Type:
cell culture: Raji B-cells; mice: SCID C·B-17
Citation Extract:
Gambles MT, Kendell I, Li J, Spainhower K, Sborov D, Owen S, Stark A, Bearss D, Yang J, Kopeček J. Two-component T-cell immunotherapy enables antigen pre-targeting to reduce cytokine release without forfeiting efficacy. Nanomedicine. 2025 Apr 30;67:102825. doi: 10.1016/j.nano.2025.102825. Epub ahead of print. PMID: 40316226.

G protein-coupled receptor GPR182 negatively regulates sprouting angiogenesis via modulating CXCL12-CXCR4 axis signaling

Authors:
Chen C, Liu W, Yuan F, Wang X, Xu X, Ling CC, Ge X, Shen X, Li B, Shen Y, Liu D
Citation:
Angiogenesis. 2025 May 2;28(3):25. doi: 10.1007/s10456-025-09977-5. PMID: 40314798; PMCID: PMC12048421
Epub:
Not Epub
Abstract:
Angiogenesis is a critical process for tumor progression, regulated by various signaling pathways. Although antiangiogenic...
Link:
https://link.springer.com/article/10.1007/s10456-025-09977-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen C, Liu W, Yuan F, Wang X, Xu X, Ling CC, Ge X, Shen X, Li B, Shen Y, Liu D. G protein-coupled receptor GPR182 negatively regulates sprouting angiogenesis via modulating CXCL12-CXCR4 axis signaling. Angiogenesis. 2025 May 2;28(3):25. doi: 10.1007/s10456-025-09977-5. PMID: 40314798; PMCID: PMC12048421.

Loss of cep57 function induces G1 arrest and microcephaly

Authors:
Iyer S, Gokhale A, Shree Murugesan P, Kumar M
Citation:
bioRxiv [preprint] 2025.04.10.648303; doi: https://doi.org/10.1101/2025.04.10.648303
Epub:
Not Epub
Abstract:
Centrosomal protein 57 (CEP57) is essential for centrosome organization, regulating nucleation and stabilization of...
Link:
https://www.biorxiv.org/content/10.1101/2025.04.10.648303v1.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iyer S, Gokhale A, Shree Murugesan P, Kumar M. Loss of cep57 function induces G1 arrest and microcephaly. bioRxiv [preprint] 2025.04.10.648303; doi: https://doi.org/10.1101/2025.04.10.648303.

A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing

Authors:
Morales Castro RA, Kern BC, Díaz-Basabe A, Meinen ER, Zhao D, Zhou Y, Castillo F, Monasterio G, Farcas V, Chávez MN, Fransson J, Villablanca EJ
Citation:
Mucosal Immunol. 2025 Apr 17:S1933-0219(25)00042-X. doi: 10.1016/j.mucimm.2025.04.004. Epub ahead of print. PMID: 40252728
Epub:
Not Epub
Abstract:
Promoting intestinal regeneration and enhancing mucosal healing have emerged as promising therapeutic alternatives for treating...
Link:
https://www.sciencedirect.com/science/article/pii/S193302192500042X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morales Castro RA, Kern BC, Díaz-Basabe A, Meinen ER, Zhao D, Zhou Y, Castillo F, Monasterio G, Farcas V, Chávez MN, Fransson J, Villablanca EJ. A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing. Mucosal Immunol. 2025 Apr 17:S1933-0219(25)00042-X. doi: 10.1016/j.mucimm.2025.04.004. Epub ahead of print. PMID: 40252728.

Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is mis-spliced in striated muscle diseases

Authors:
Gentile GM, Blue RE, Goda GA, Guzman BB, Szymanski RA, Lee EY, Engels NM, Hinkle ER, Wiedner HJ, Bishop AN, Harrison JT, Zhang H, Wehrens XHT, Dominguez D, Giudice J
Citation:
RNA Biol. 2025 Apr 10. doi: 10.1080/15476286.2025.2491160. Epub ahead of print. PMID: 40207498
Epub:
Not Epub
Abstract:
The reprogramming of alternative splicing networks during development is a hallmark of tissue maturation and identity....
Link:
https://www.tandfonline.com/doi/full/10.1080/15476286.2025.2491160
Delivery Method:
electroporation
Organism or Cell Type:
C2C12 myoblast cells
Citation Extract:
Gentile GM, Blue RE, Goda GA, Guzman BB, Szymanski RA, Lee EY, Engels NM, Hinkle ER, Wiedner HJ, Bishop AN, Harrison JT, Zhang H, Wehrens XHT, Dominguez D, Giudice J. Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is mis-spliced in striated muscle diseases. RNA Biol. 2025 Apr 10. doi: 10.1080/15476286.2025.2491160. Epub ahead of print. PMID: 40207498.

Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy

Authors:
Dogra D, Phan VA, Zhang S, Gavrilovici C, DiMarzo N, Narang A, Ibhazehiebo K, Kurrasch DM
Citation:
PLoS Biol. 2025 Apr 10;23(4):e3002499. doi: 10.1371/journal.pbio.3002499. Epub ahead of print. PMID: 40208862
Epub:
Not Epub
Abstract:
SLC13A5 encodes a citrate transporter highly expressed in the brain and is important for regulating intra- and extracellular...
Link:
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002499
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dogra D, Phan VA, Zhang S, Gavrilovici C, DiMarzo N, Narang A, Ibhazehiebo K, Kurrasch DM. Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy. PLoS Biol. 2025 Apr 10;23(4):e3002499. doi: 10.1371/journal.pbio.3002499. Epub ahead of print. PMID: 40208862.

Pulmonary mitochondrial DNA release and activation of the cGAS-STING pathway in Lethal Stx12 knockout mice

Authors:
Liu DH, Li F, Yang RZ, Wu Z, Meng XY, Li SM, Li WX, Li JK, Wang DD, Wang RY, Li SA, Liu PP, Kang JS
Citation:
Cell Commun Signal. 2025 Apr 8;23(1):174. doi: 10.1186/s12964-025-02141-y. PMID: 40200300; PMCID: PMC11980072
Epub:
Not Epub
Abstract:
STX12 (syntaxin12 or syntaxin13), a member of the SNARE protein family, plays a crucial role in intracellular vesicle transport...
Link:
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-025-02141-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu DH, Li F, Yang RZ, Wu Z, Meng XY, Li SM, Li WX, Li JK, Wang DD, Wang RY, Li SA, Liu PP, Kang JS. Pulmonary mitochondrial DNA release and activation of the cGAS-STING pathway in Lethal Stx12 knockout mice. Cell Commun Signal. 2025 Apr 8;23(1):174. doi: 10.1186/s12964-025-02141-y. PMID: 40200300; PMCID: PMC11980072.

Pages