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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12428 scientific papers returned from the database with the search filters currently being used below.
There are 12428 scientific papers returned from the database with the search filters currently being used below.
Antisense Oligonucleotides Targeting the SARS-CoV-2 Nucleocapsid Gene Decrease Viral Titers in Hamsters
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Citation:
Molecular Therapy - Nucleic Acids (2025) Epub:
Not Epub Abstract:
SARS-CoV-2 is a positive, single-stranded RNA coronavirus responsible for the COVID-19 pandemic. The emergence of new variants... Delivery Method:
Lipofectamine 2000 for cell culture; intranasal for hamsters Organism or Cell Type:
cell culture: HEK-293T/ACE2; in vivo: Syrian hamsters Citation Extract: Fitzpatrick C, Meunier N, Lepoder S, Dhorne-Pollet S, Da Costa B, Klonjkowki B, Eléouët J-F, Burzio VA, Delmas B, Barrey E. Antisense Oligonucleotides Targeting the SARS-CoV-2 Nucleocapsid Gene Decrease Viral Titers in Hamsters. Molecular Therapy - Nucleic Acids (2025). |
New facets of zona pellucida (ZP) proteins: called oocyte-specific, yet produced by the preimplantation embryo and needed for blastocyst formation
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Citation:
Human Reproduction, Volume 40, Issue Supplement_1, June 23, 2025 Epub:
Not Epub Abstract:
Study question: What does a secreted oocyte-specific protein, ZP2, do inside mouse embryos during cleavage?
Summary answer:... Delivery Method:
microinjection Organism or Cell Type:
mouse embryo Citation Extract: Boiani M, Fuellen G, Drexler H, Israel S, Heinrich I, Nolte T. New facets of zona pellucida (ZP) proteins: called oocyte-specific, yet produced by the preimplantation embryo and needed for blastocyst formation. Human Reproduction, Volume 40, Issue Supplement_1, June 23, 2025. |
Semaphorin 3F is elevated in serum of heart failure patients and inhibits cardiac angiogenesis via the VEGF/Akt/eNOS pathway
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Citation:
Journal Molecular and Cellular Cardiology Plus. Volume 13, September 2025, 100470 Epub:
Not Epub Abstract:
Left ventricular (LV) remodeling in heart failure (HF) is associated with vascular rarefaction and impaired angiogenesis. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Petrova D, Weberbauer M, Reichert S, Scheid S, Esser J, Fink K, Duerschmied D, Moser M, Helbing T. Semaphorin 3F is elevated in serum of heart failure patients and inhibits cardiac angiogenesis via the VEGF/Akt/eNOS pathway. Journal Molecular and Cellular Cardiology Plus. Volume 13, September 2025, 100470. |
Aberrant activation of IL-6/JAK/STAT3/FOSL1 signaling induces renal abnormalities in a Xenopus model of Joubert syndrome-related disorders
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Citation:
J Biol Chem. 2025 Jun 24:110413. doi: 10.1016/j.jbc.2025.110413. Epub ahead of print. PMID: 40570958 Epub:
Not Epub Abstract:
CEP290 gene mutations are linked to Joubert syndrome-related disorders (JSRD) which present with various symptoms including... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Uuganbayar U, Ninomiya H, Shimada IS, Yamada C, Kanie M, Kawai S, Asai T, Miyoshi-Akiyama T, Itoh M, Hashimoto Y, Kato Y. Aberrant activation of IL-6/JAK/STAT3/FOSL1 signaling induces renal abnormalities in a Xenopus model of Joubert syndrome-related disorders. J Biol Chem. 2025 Jun 24:110413. doi: 10.1016/j.jbc.2025.110413. Epub ahead of print. PMID: 40570958. |
Reversal of cerebrovascular anomalies in a zebrafish model of vein of Galen aneurysm
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Citation:
Nat Cardiovasc Res. 2025 Jun;4(6):773-789. doi: 10.1038/s44161-025-00659-5. Epub 2025 Jun 12. PMID: 40506481 Epub:
Not Epub Abstract:
Congenital vascular malformations result from abnormal development of the vascular tree, with the aneurysmal malformation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Martin-Valiente E, Du Y, Goemans C, America M, Zindy E, Adam M, Scheid B, Vikkula M, Lubicz B, Vanhollebeke B, Baeyens N. Reversal of cerebrovascular anomalies in a zebrafish model of vein of Galen aneurysm. Nat Cardiovasc Res. 2025 Jun;4(6):773-789. doi: 10.1038/s44161-025-00659-5. Epub 2025 Jun 12. PMID: 40506481. |
Transcriptome Remodelling and Changes in Growth and Cardiometabolic Phenotype Result following Grb10a Knockdown in the Early Life of the Zebrafish
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Citation:
Cellular and Molecular Life Sciences. 2025 Jun 3 Epub:
Not Epub Abstract:
Embryonic growth trajectory is a risk factor for chronic metabolic and cardiovascular disorders. Grb10 is a negative regulator... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Evans BL, Garner T, De Leonibus C, Wright L, Sharps M, Wearing OH, Ripley DM, Shiels HA, Hurlstone AFL, Clayton PE, Stevens A. Transcriptome Remodelling and Changes in Growth and Cardiometabolic Phenotype Result following Grb10a Knockdown in the Early Life of the Zebrafish. Cellular and Molecular Life Sciences. 2025 Jun 3. |
cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish
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Citation:
EMBO J. 2025 Jun 9. doi: 10.1038/s44318-025-00482-5. Epub ahead of print. PMID: 40490553 Epub:
Not Epub Abstract:
Telomere shortening occurs in multiple tissues throughout aging. When telomeres become critically short, they trigger DNA-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Şerifoğlu N, Allavena G, Lopes-Bastos B, Marzullo M, Marques A, Colibert P, Bousounis P, Trompouki E, Ferreira MG. cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish. EMBO J. 2025 Jun 9. doi: 10.1038/s44318-025-00482-5. Epub ahead of print. PMID: 40490553. |
BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD
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Citation:
bioRxiv [Preprint]. 2025 Mar 10:2024.08.27.608867. doi: 10.1101/2024.08.27.608867. PMID: 39253489; PMCID: PMC11383298 Epub:
Not Epub Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is primarily of adult-onset and caused by pathogenic variants in PKD1 or... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Tran U, Streets AJ, Smith D, Decker E, Kirschfink A, Izem L, Hassey JM, Rutland B, Valluru MK, Bräsen JH, Ott E, Epting D, Eisenberger T, Ong AC, Bergmann C, Wessely O. BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD. bioRxiv [Preprint]. 2025 Mar 10:2024.08.27.608867. doi: 10.1101/2024.08.27.608867. PMID: 39253489; PMCID: PMC11383298. |
A Cell Type-Specific Role for Tubb6 in Ciliogenesis of Xenopus Epidermal Multiciliated Cells
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Citation:
bioRxiv [preprint] 2025.05.31.657203; doi: https://doi.org/10.1101/2025.05.31.657203 Epub:
Not Epub Abstract:
Cilia are microtubule-based organelles found on the surface of most eukaryotic cells. These microtubules are composed of α- and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Xu X, Ross J, Clark F, Wei S, Sun J. A Cell Type-Specific Role for Tubb6 in Ciliogenesis of Xenopus Epidermal Multiciliated Cells. bioRxiv [preprint] 2025.05.31.657203; doi: https://doi.org/10.1101/2025.05.31.657203. |
The Potential Role of Gonadotropic Hormones and Their Receptors in Sex Differentiation of Nile Tilapia, Oreochromis niloticus
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Citation:
International Journal of Molecular Sciences. 2025; 26(11):5376. https://doi.org/10.3390/ijms26115376 Epub:
Not Epub Abstract:
Nile tilapia, as an ideal model for studying sex differentiation, is a popular farmed fish worldwide with a stable XX/XY sex-... Delivery Method:
microinjection Organism or Cell Type:
Nile tilapia Citation Extract: Gao H, Yan H, Arai T, Aranyakanont C, Li S, Ijiri S. The Potential Role of Gonadotropic Hormones and Their Receptors in Sex Differentiation of Nile Tilapia, Oreochromis niloticus. International Journal of Molecular Sciences. 2025; 26(11):5376. https://doi.org/10.3390/ijms26115376. |