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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Conception and synthesis of sequence-coded morpholinos
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Citation:
Chemistry. 2025 Apr 14:e202501161. doi: 10.1002/chem.202501161. Epub ahead of print. PMID: 40227092 Epub:
Not Epub Abstract:
Solid-phase morpholino chemistry was explored as a new route to synthesize abiological sequence-defined oligomers. Two... Delivery Method:
None Organism or Cell Type:
None Citation Extract: Pousse B, Al Ouahabi A, Baxter PNW, Charles L, Lutz JF. Conception and synthesis of sequence-coded morpholinos. Chemistry. 2025 Apr 14:e202501161. doi: 10.1002/chem.202501161. Epub ahead of print. PMID: 40227092. |
The cohesin-associated protein Pds5A governs the meiotic spindle assembly via deubiquitination of Kif5B in oocytes
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Citation:
Sci Adv. 2025 Apr 11;11(15):eadt6159. doi: 10.1126/sciadv.adt6159. Epub 2025 Apr 11. PMID: 40215310; PMCID: PMC11988415 Epub:
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Chromosome cohesion mediated by cohesin complex and its associated proteins is required for accurate chromosome segregation and... Delivery Method:
microinjection Organism or Cell Type:
ICR mouse oocyst Citation Extract: Zhang Y, Bai J, Xiong B. The cohesin-associated protein Pds5A governs the meiotic spindle assembly via deubiquitination of Kif5B in oocytes. Sci Adv. 2025 Apr 11;11(15):eadt6159. doi: 10.1126/sciadv.adt6159. Epub 2025 Apr 11. PMID: 40215310; PMCID: PMC11988415. |
Far-red fluorescent genetically encoded calcium ion indicators
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Citation:
Nat Commun. 2025 Apr 7;16(1):3318. doi: 10.1038/s41467-025-58485-z. PMID: 40195305 Epub:
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Genetically encoded calcium ion (Ca2+) indicators (GECIs) are widely-used molecular tools for functional imaging of Ca2+... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dalangin R, Jia BZ, Qi Y, Aggarwal A, Sakoi K, Drobizhev M, Molina RS, Patel R, Abdelfattah AS, Zheng J, Reep D, Hasseman JP; GENIE Project Team; Zhao Y, Wu J, Podgorski K, Tebo AG, Schreiter ER, Hughes TE, Terai T, Paquet ME, Megason SG, Cohen AE, Shen Y, Campbell RE. Far-red fluorescent genetically encoded calcium ion indicators. Nat Commun. 2025 Apr 7;16(1):3318. doi: 10.1038/s41467-025-58485-z. PMID: 40195305. |
Curcumin-mediated NRF2 induction limits inflammatory damage in, preclinical models of cystic fibrosis
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Citation:
Biomed Pharmacother. 2025 Mar 31;186:117957. doi: 10.1016/j.biopha.2025.117957. Epub ahead of print. PMID: 40168724 Epub:
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Background: Overactive neutrophilic inflammation causes damage to the airways and death in people with cystic fibrosis (CF), a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Leon-Icaza SA, Frétaud M, Cornélie S, Bureau C, Yatime L, Floto RA, Renshaw SA, Herrmann JL, Langevin C, Cougoule C, Bernut A. Curcumin-mediated NRF2 induction limits inflammatory damage in, preclinical models of cystic fibrosis. Biomed Pharmacother. 2025 Mar 31;186:117957. doi: 10.1016/j.biopha.2025.117957. Epub ahead of print. PMID: 40168724. |
Probe-Screened Carbon Nanotube Field-Effect Transistor Biosensor to Enhance Breast Cancer-Related Gene Assay
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Citation:
Green Analytical Chemistry (2025) 100267, ISSN 2772-5774, doi.org/10.1016/j.greeac.2025.100267 Epub:
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BRCA1 gene testing is a trump card for liquid biopsy and early diagnosis in breast cancer, which has been limited, however, by... Delivery Method:
None Organism or Cell Type:
DNA samples extracted from BRCA1-mutated breast cancer patients and healthy controls Citation Extract: Liu P, Liu Y, Cai B, Li J, Zhang G-J. Probe-Screened Carbon Nanotube Field-Effect Transistor Biosensor to Enhance Breast Cancer-Related Gene Assay. Green Analytical Chemistry (2025) 100267, ISSN 2772-5774, doi.org/10.1016/j.greeac.2025.100267. |
Evi1 is necessary for late activation of delta-notch signaling in sea urchin embryos
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Citation:
bioRxiv [preprint] 2025.04.01.646662; doi: https://doi.org/10.1101/2025.04.01.646662 Epub:
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Embryonic mesoderm specification and differentiation rely on intricate gene regulatory networks. In sea urchin embryos,... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Anand S & McClay D. Evi1 is necessary for late activation of delta-notch signaling in sea urchin embryos. bioRxiv [preprint] 2025.04.01.646662; doi: https://doi.org/10.1101/2025.04.01.646662. |
SMC2 and Condensin II Subunits Are Essential for the Development of Hematopoietic Stem and Progenitor Cells in Zebrafish
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Citation:
J Cell Physiol. 2025 Mar;240(3):e70023. doi: 10.1002/jcp.70023. PMID: 40134128; PMCID: PMC11937623 Epub:
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Hematopoietic stem and progenitor cells (HSPCs) play a pivotal role in blood cell production, maintaining the health and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oh CK, Kim MS, Shin U, Kang JW, Kim YH, Ko HS, Ra JS, Ahn S, Choi EY, Yu S, Nam U, Choi T, Myung K, Lee Y. SMC2 and Condensin II Subunits Are Essential for the Development of Hematopoietic Stem and Progenitor Cells in Zebrafish. J Cell Physiol. 2025 Mar;240(3):e70023. doi: 10.1002/jcp.70023. PMID: 40134128; PMCID: PMC11937623. |
Zebrafish TDP43 positively regulates p65-mediated apoptotic pathway
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Citation:
Int J Biol Macromol. 2025 Mar 27:142599. doi: 10.1016/j.ijbiomac.2025.142599. Epub ahead of print. PMID: 40157684 Epub:
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TAR DNA-binding protein 43 (TDP43) is a multifunctional RNA/DNA binding protein that serves as a hallmark of neurodegeneration... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu T, Li M, Li M, Zhang Q, Zhang H, Jiang Z, Wang S, Mao H, Li D, Fan L, Hu C, Xu X. Zebrafish TDP43 positively regulates p65-mediated apoptotic pathway. Int J Biol Macromol. 2025 Mar 27:142599. doi: 10.1016/j.ijbiomac.2025.142599. Epub ahead of print. PMID: 40157684. |
OPN3-mediated positive regulation of angiogenesis in HUVECs through VEGFR2 interaction
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Citation:
Commun Biol. 2025 Mar 31;8(1):529. doi: 10.1038/s42003-025-07958-4. PMID: 40164822; PMCID: PMC11958745 Epub:
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Many rhodopsin-like G-protein-coupled receptors (Rh-GPCRs) are known to either promote or inhibit angiogenesis. Among these,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Luo H, Zhang W, Zeng W, Wang Y, Feng J, Lan Y, Dong X, Liu T, Sun Y, Lu H. OPN3-mediated positive regulation of angiogenesis in HUVECs through VEGFR2 interaction. Commun Biol. 2025 Mar 31;8(1):529. doi: 10.1038/s42003-025-07958-4. PMID: 40164822; PMCID: PMC11958745. |
Cryo-EM structure of the BLOC-3 complex provides insights into the pathogenesis of Hermansky-Pudlak syndrome
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Citation:
Nat Commun. 2025 Mar 26;16(1):2967. doi: 10.1038/s41467-025-58235-1. PMID: 40140412; PMCID: PMC11947305 Epub:
Not Epub Abstract:
Biogenesis of lysosome-related organelle complex-3 (BLOC-3) is pivotal in vesicle trafficking and has been linked to Hermansky-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yong X, Jia G, Yang Q, Zhou C, Zhang S, Deng H, Billadeau DD, Su Z, Jia D. Cryo-EM structure of the BLOC-3 complex provides insights into the pathogenesis of Hermansky-Pudlak syndrome. Nat Commun. 2025 Mar 26;16(1):2967. doi: 10.1038/s41467-025-58235-1. PMID: 40140412; PMCID: PMC11947305. |