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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
TRAP1 functions in the morphogenesis of the embryonic kidney
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Citation:
Anim Cells Syst (Seoul). 2025 Mar 12;29(1):9-18. doi: 10.1080/19768354.2025.2477789. PMID: 40098710; PMCID: PMC11912273 Epub:
Not Epub Abstract:
TNF receptor-associated protein1 (TRAP1) is a mitochondrial molecular chaperon with high homology with a cytosolic chaperon... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kim HE, Kwon T, Sim HJ, Park TJ
. TRAP1 functions in the morphogenesis of the embryonic kidney. Anim Cells Syst (Seoul). 2025 Mar 12;29(1):9-18. doi: 10.1080/19768354.2025.2477789. PMID: 40098710; PMCID: PMC11912273. |
Elf1 Deficiency Impairs Macrophage Development in Zebrafish Model Organism
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Citation:
International Journal of Molecular Sciences. 2025; 26(6):2537. https://doi.org/10.3390/ijms26062537 Epub:
Not Epub Abstract:
The Ets (E-twenty-six) family of transcription factors plays a critical role in hematopoiesis and myeloid differentiation.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tan Q, Wang J, Hao Y, Yang S, Cao B, Pan W, Cao M. Elf1 Deficiency Impairs Macrophage Development in Zebrafish Model Organism . International Journal of Molecular Sciences. 2025; 26(6):2537. https://doi.org/10.3390/ijms26062537. |
TBK1 is involved in programmed cell death and ALS-related pathways in novel zebrafish models
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Citation:
Cell Death Discov. 2025 Mar 12;11(1):98. doi: 10.1038/s41420-025-02374-3. PMID: 40075110; PMCID: PMC11903655 Epub:
Not Epub Abstract:
Pathogenic mutations within the TBK1 gene leading to haploinsufficiency are causative of amyotrophic lateral sclerosis (ALS).... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Raas Q, Haouy G, de Calbiac H, Pasho E, Marian A, Guerrera IC, Rosello M, Oeckl P, Del Bene F, Catanese A, Ciura S, Kabashi E. TBK1 is involved in programmed cell death and ALS-related pathways in novel zebrafish models. Cell Death Discov. 2025 Mar 12;11(1):98. doi: 10.1038/s41420-025-02374-3. PMID: 40075110; PMCID: PMC11903655. |
PRMT5-mediated arginine methylation stabilizes GPX4 to suppress ferroptosis in cancer
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Citation:
Nat Cell Biol. 2025 Mar 3. doi: 10.1038/s41556-025-01610-3. Epub ahead of print. PMID: 40033101 Epub:
Not Epub Abstract:
The activation of ferroptosis has shown great potential for cancer therapy from an unconventional perspective, but revealing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fan Y, Wang Y, Dan W, Zhang Y, Nie L, Ma Z, Zhuang Y, Liu B, Li M, Liu T, Wang Z, Ye L, Wei Y, Lei Y, Guo C, An J, Wang C, Zhang Y, Zeng J, Wei W, Gan B, Li L. PRMT5-mediated arginine methylation stabilizes GPX4 to suppress ferroptosis in cancer. Nat Cell Biol. 2025 Mar 3. doi: 10.1038/s41556-025-01610-3. Epub ahead of print. PMID: 40033101. |
Zebrafish (Danio rerio) TDP43 negatively regulates PKZ-IRF3–mediated IFN I response
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Citation:
The Journal of Immunology, 2025;, vkae035, https://doi.org/10.1093/jimmun/vkae035 Epub:
Not Epub Abstract:
Transactive response DNA binding protein 43 kD (TDP43), encoded by the tardbp gene, is a member of heterogenous nuclear... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu T, Li M-M, Li M-F, Wang S, Feng Z, Zhang H, Liu J, Mao H, Li D, Hu C, Xu X. Zebrafish (Danio rerio) TDP43 negatively regulates PKZ-IRF3–mediated IFN I response. The Journal of Immunology, 2025;, vkae035, https://doi.org/10.1093/jimmun/vkae035. |
Novel MYH10 heterozygous variants associated to a syndrome combining mainly ptosis and ocular coloboma expand the MYH10 related phenotypes
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Citation:
Eur J Hum Genet. 2025 Mar 5. doi: 10.1038/s41431-025-01803-2. Epub ahead of print. PMID: 40044823 Epub:
Not Epub Abstract:
Syndromes associating both eyeball and periocular developmental anomalies, combining iris chorioretinal (ocular) coloboma and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scheidecker S, Bär S, Kröll-Hermi A, Delvallée C, Rinaldi B, Korpioja A, Geoffroy V, Schaefer E, Secula S, Jaeger C, Stoetzel C, Kassel O, Straehle U, Bertoli-Avella A, Zonic E, Lamouche JB, Zanlonghi X, Etard C, Muller J, Rahikkala E, Friant S, Dollfus H. Novel MYH10 heterozygous variants associated to a syndrome combining mainly ptosis and ocular coloboma expand the MYH10 related phenotypes. Eur J Hum Genet. 2025 Mar 5. doi: 10.1038/s41431-025-01803-2. Epub ahead of print. PMID: 40044823. |
Trivalent siRNA-Conjugates with Guanosine as ASGPR-Binder Show Potent Knock-Down In Vivo
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Citation:
J Med Chem. 2025 Mar 7. doi: 10.1021/acs.jmedchem.4c02275. Epub ahead of print. PMID: 40052708 Epub:
Not Epub Abstract:
To increase the chemical space around the well-known GalNAc-ligand as ASGPR-binder, a high-throughput screening campaign was... Citation Extract: Hofmeister A, Jahn-Hofmann K, Brunner B, Helms M, Metz-Weidmann C, Poeverlein C, Zech G, Li Z, Hessler G, Schreuder H, Elshorst B, Krack A, Kurz M, Heubel C, Scheidler S. Trivalent siRNA-Conjugates with Guanosine as ASGPR-Binder Show Potent Knock-Down In Vivo. J Med Chem. 2025 Mar 7. doi: 10.1021/acs.jmedchem.4c02275. Epub ahead of print. PMID: 40052708. |
Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells
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Citation:
Mol Ther Nucleic Acids. 2024 Dec 21;36(1):102443. doi: 10.1016/j.omtn.2024.102443. PMID: 39967852; PMCID: PMC11834094 Epub:
Not Epub Abstract:
Dysferlinopathies are debilitating autosomal recessive muscular dystrophies caused by mutations in the DYSF gene, encoding... Delivery Method:
Endo-Porter Organism or Cell Type:
patient-derived myoblasts and differentiated myotubes Citation Extract: Anwar S, Roshmi RR, Woo S, Haque US, Arthur Lee JJ, Duddy WJ, Bigot A, Maruyama R, Yokota T. Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells. Mol Ther Nucleic Acids. 2024 Dec 21;36(1):102443. doi: 10.1016/j.omtn.2024.102443. PMID: 39967852; PMCID: PMC11834094. |
Human colonic EVs induce murine enteric neuroplasticity via the lncRNA GAS5/miR-23/NMDA NR2B axis
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Citation:
JCI Insight. 2025 Mar 10;10(5):e178631. doi: 10.1172/jci.insight.178631. PMID: 40059833 Epub:
Not Epub Abstract:
Postinfectious, diarrhea-predominant, irritable bowel syndrome (PI-IBS-D) is difficult to treat owing to its unknown... Delivery Method:
Vivo-Morpholino; intraperitoneal (i.p.) Organism or Cell Type:
Rab27a/b–/– mice Citation Extract: Zhou Q, Yang L, Verne ZT, Zhang BB, Fields JZ, Thacker AT, Verne GN. Human colonic EVs induce murine enteric neuroplasticity via the lncRNA GAS5/miR-23/NMDA NR2B axis. JCI Insight. 2025 Mar 10;10(5):e178631. doi: 10.1172/jci.insight.178631. PMID: 40059833. |
Srebf2 mediates successful optic nerve axon regeneration via the mevalonate synthesis pathway
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Citation:
Mol Neurodegener. 2025 Mar 5;20(1):28. doi: 10.1186/s13024-025-00807-2. PMID: 40045384; PMCID: PMC11883989 Epub:
Not Epub Abstract:
Background: Axon regeneration within the mammalian central nervous system is extremely limited. In optic neuropathy conditions... Delivery Method:
gel foam soaked in MO placed on distal optic nerve stump Organism or Cell Type:
zebrafish Citation Extract: Hu M, Veldman MB. Srebf2 mediates successful optic nerve axon regeneration via the mevalonate synthesis pathway. Mol Neurodegener. 2025 Mar 5;20(1):28. doi: 10.1186/s13024-025-00807-2. PMID: 40045384; PMCID: PMC11883989. |